Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Act-709478
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 PubChem ID
CID: 118560618
Canonical SMILES
FC(F)(F)C1(CC1)c1ccc(CC(=O)Nc2ccn(Cc3ccc(cn3)C#N)n2)cc1
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Compound Formula C22H18F3N5O
Compound Structure
Protein Name
 Protein Info 
Voltage-dependent T-type calcium channel subunit alpha-1I
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
Q9P0X4
Gene Name
CACNA1I
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.5 nM
   TI
   LI
   LO
   TS