Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02179 , Cyclin-dependent kinase 14
Gene Name CDK14
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID O94921
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02179
 
Compound ID Compound Name Compound Formula
CP0029567
4-[(2-chloro-6-methoxybenzoyl)amino]-N-[1-[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C31H35ClF3N7O8S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0029570
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C30H32Cl2F3N7O7S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0029990
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]phenyl]methyl]piperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C31H34Cl2F3N7O5
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0034077
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[3-(prop-2-enoylamino)benzoyl]piperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C28H25Cl2F3N6O6
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0024531
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[3-[[(E)-5-(dimethylamino)pent-2-enoyl]amino]phenyl]piperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C31H34Cl2F3N7O5
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0030577
4-benzamido-N-[1-[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C30H34F3N7O7S
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0033254
4-[(2,6-dichlorobenzoyl)amino]-N-[4-[[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzoyl]amino]phenyl]-1H-pyrazole-3-carboxamide;2,2,2-trifluoroacetic acid
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C32H28Cl2F3N7O6
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0034078
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[3-(prop-2-enoylamino)phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C27H25Cl2F3N6O7S
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0638634
(E)-N-(1-(3-(4-(dimethylamino)but-2-enamido)phenylsulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide 2,2,2-trifluoroacetate
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C30H31Cl3F3N7O7S
 1
1
IC50 >= 500 nM
   TI
   LI
   LO
   TS
CP0023548
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[3-(propanoylamino)phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C27H27Cl2F3N6O7S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0023550
4-[(2,6-dichlorobenzoyl)amino]-N-[(3R)-1-[4-[[(E)-5-(dimethylamino)pent-2-enoyl]amino]phenyl]sulfonylpyrrolidin-3-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C30H32Cl2F3N7O7S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0023555
4-[(2,6-dimethoxybenzoyl)amino]-N-[1-[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C32H38F3N7O9S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0029575
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[[3-(propanoylamino)phenyl]methyl]piperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C28H29Cl2F3N6O5
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0032508
N-[1-[3-(prop-2-enoylamino)phenyl]sulfonylpiperidin-4-yl]-4-[(2,4,6-trimethoxybenzoyl)amino]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
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C30H33F3N6O10S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS