Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02079 , Gonadotropin-releasing hormone receptor
 Protein Info 
Gene Name GNRHR
Organism Macaca mulatta, Rhesus macaque
Protein Classification Membrane receptor
Uniprot ID Q8SPZ1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT02079
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0455438
 Compound Info 
4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[(2-fluoro-6-methylphenyl)methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
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C32H33F2N3O5
  1
1
IC50 = 3.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463546
 Compound Info 
4-[[(1R)-2-[5-[4-(2-fluoro-3-methoxyphenyl)piperazin-1-yl]-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
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C36H38F5N5O5
  2
1
IC50 = 3.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 32.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0460559
 Compound Info 
4-[[(1R)-2-[3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxo-5-[4-[[5-(trifluoromethyl)furan-2-yl]methyl]piperazin-1-yl]pyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
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C35H36F7N5O5
  2
1
IC50 = 3.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 13.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0476950
 Compound Info 
4-[[(1R)-2-[3-[(2-fluoro-6-methylphenyl)methyl]-4-methyl-2,6-dioxo-5-[4-[[5-(trifluoromethyl)furan-2-yl]methyl]piperazin-1-yl]pyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
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C35H39F4N5O5
  1
1
IC50 = 3.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0473822
 Compound Info 
4-[[(1R)-2-[3-[(2,6-difluorophenyl)methyl]-4-methyl-2,6-dioxo-5-[4-[[5-(trifluoromethyl)furan-2-yl]methyl]piperazin-1-yl]pyrimidin-1-yl]-1-(3-fluoro-5-methylphenyl)ethyl]amino]butanoic acid
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C35H37F6N5O5
  1
1
IC50 = 4.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS