Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[(1R)-2-[5-[4-(2-fluoro-3-methoxyphenyl)piperazin-1-yl]-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
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 PubChem ID
CID: 155531714
Canonical SMILES
COc1cccc(N2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](NCCCC(O)=O)c3ccccc3)c2=O)c1F
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Compound Formula C36H38F5N5O5
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
Q8SPZ1
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 32.4 nM
   TI
   LI
   LO
   TS