Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01920 , Cyclin-G-associated kinase
Gene Name GAK
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID O14976
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01920
 
Compound ID Compound Name Compound Formula
CP0110399
4-Anilino-3-cyanoquinoline deriv. 4
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C21H21N3O5
 1
1
IC50 = 2.4 nM
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CP0099872
4-Anilinoquinoline deriv. 8
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C20H22N2O5
 1
1
IC50 = 23 nM
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CP0569632
4-(3-ethynylanilino)-6,7-dimethoxyquinoline-3-carbonitrile
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C20H15N3O2
 1
1
IC50 = 31 nM
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CP0180553
6-bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
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C18H17BrN2O3
 1
1
IC50 = 48 nM
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CP0183162
(6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-phenyl)-amine
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C18H15N3O2
 1
1
IC50 = 72 nM
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CP0289874
4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile
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C18H14BrN3O2
 1
1
IC50 = 130 nM
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CP0245015
6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
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C19H17F3N2O3
 1
1
IC50 = 170 nM
   TI
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CP0011998
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
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C16H14BrN3O2
 1
1
IC50 = 260 nM
   TI
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   TS
CP0363886
6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine
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C19H21N3O5
 1
1
IC50 = 350 nM
   TI
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CP0036082
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
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C22H24ClFN4O3
 1
1
IC50 = 420 nM
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CP0294002
N-(3-ethynylphenyl)-6,7-dimethoxyquinolin-4-amine
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C19H16N2O2
 1
1
IC50 = 500 nM
   TI
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CP0438056
(3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-amine
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C17H15BrN2O2
 1
1
IC50 = 510 nM
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CP0037987
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
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C22H23N3O4
 1
1
IC50 = 910 nM
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CP0402833
6,7-bis(2-methoxyethoxy)-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine
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C23H29N3O7
 1
1
IC50 = 2600 nM
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CP0307724
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinolin-4-amine
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C23H24N2O4
 1
1
IC50 = 4200 nM
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CP0423044
N-[6-[3-[(4-fluorophenyl)methylsulfonylamino]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C24H21FN4O3S
 1
1
IC50 = 9240 nM
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CP0489852
N-[6-[3-(propylsulfonylamino)phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C20H22N4O3S
 1
1
IC50 = 9250 nM
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CP0423041
N-[6-[3-[(3-fluorophenyl)methylsulfonylamino]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C24H21FN4O3S
 1
1
IC50 > 10000 nM
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CP0423042
N-[6-[3-[[[methyl(2,2,2-trifluoroethyl)sulfamoyl]amino]methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C21H22F3N5O3S
 1
1
IC50 > 10000 nM
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CP0423043
N-[6-[3-[(2-methylpropylsulfonylamino)methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C22H26N4O3S
 1
1
IC50 > 10000 nM
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CP0423045
N-[6-[3-[(cyclopropylmethylsulfonylamino)methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C22H24N4O3S
 1
1
IC50 > 10000 nM
   TI
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CP0423046
N-[6-[3-(cyclopropylsulfonylamino)phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C20H20N4O3S
 1
1
IC50 > 10000 nM
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CP0469511
N-[6-[3-(diethylsulfamoylamino)phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
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C21H25N5O3S
 1
1
IC50 > 10000 nM
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CP0474150
N-[6-[3-[(2-fluorophenyl)methylsulfonylamino]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C24H21FN4O3S
 1
1
IC50 > 10000 nM
   TI
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CP0474151
N-[6-[3-[[[ethyl(methyl)sulfamoyl]amino]methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C21H25N5O3S
 1
1
IC50 > 10000 nM
   TI
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CP0489853
N-[6-[3-[(3,3,3-trifluoropropylsulfonylamino)methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C21H21F3N4O3S
 1
1
IC50 > 10000 nM
   TI
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CP0519352
N-[6-[3-(cyclobutylsulfonylamino)phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C21H22N4O3S
 1
1
IC50 > 10000 nM
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CP0519634
N-[6-[3-[(2,2,2-trifluoroethylsulfonylamino)methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C20H19F3N4O3S
 1
1
IC50 > 10000 nM
   TI
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CP0542395
N-[6-[3-[[ethyl(methyl)sulfamoyl]amino]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C20H23N5O3S
 1
1
IC50 > 10000 nM
   TI
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CP0555200
N-[6-[3-(2-methylpropylsulfonylamino)phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C21H24N4O3S
 1
1
IC50 > 10000 nM
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CP0555201
N-[6-[3-[(diethylsulfamoylamino)methyl]phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
   Show/Hide
C22H27N5O3S
 1
1
IC50 > 10000 nM
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