Brief Information of the Compound and Protein
Compound Name
6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
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PubChem ID
CID: 44532526
Canonical SMILES
COc1cc(Nc2ccnc3ccc(cc23)C(F)(F)F)cc(OC)c1OC
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Compound Formula C19H17F3N2O3
Compound Structure
Protein Name
Cyclin-G-associated kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase NAK family
Uniprot ID
O14976
Gene Name
GAK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 210 nM
2 Kd = 31 nM