Compound ID |
Compound Name |
Compound Formula |
CP0041255
|
(+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide
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|
C28H39N3O2
|
2
|
1 |
IC50 = 0.8 nM
|
|
|
2 |
Ki = 16.6 nM
|
|
|
CP0548660
|
(S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{(S)-1-[(S)-1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid
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|
C38H53N7O11
|
1
|
1 |
IC50 = 1 nM
|
|
|
CP0464955
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-4-(2-amino-2-oxoethyl)-3-oxo-2,5-dihydro-1H-benzo[g][2]benzazepin-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C33H42N8O5
|
1
|
1 |
IC50 = 1 nM
|
|
|
CP0552739
|
(2S)-2-amino-N-[(2R)-1-[[(2S)-4-(2-amino-2-oxoethyl)-3-oxo-2,5-dihydro-1H-benzo[g][2]benzazepin-2-yl]amino]-1-oxopropan-2-yl]-3-(4-hydroxy-2,6-dimethylphenyl)-N-methylpropanamide
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|
C31H37N5O5
|
1
|
1 |
IC50 = 1.47 nM
|
|
|
CP0550386
|
(2S)-2-amino-N-[(2R)-1-[[(2S)-4-(2-amino-2-oxoethyl)-3-oxo-2,5-dihydro-1H-benzo[g][2]benzazepin-2-yl]amino]-1-oxopropan-2-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
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|
C30H35N5O5
|
1
|
1 |
IC50 = 2.07 nM
|
|
|
CP0038385
|
3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl)-1H-1,2,4-triazol-1-yl)phenol
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|
C21H26N4O
|
1
|
1 |
IC50 = 5.8 nM
|
|
|
CP0386949
|
(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-(2-ethenylphenyl)propanamide
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|
C27H35N5O5
|
1
|
1 |
IC50 = 8 nM
|
|
|
CP0545965
|
2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]acetic acid
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|
C28H39N7O6
|
1
|
1 |
IC50 = 14 nM
|
|
|
CP0393121
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(2-ethenylphenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C30H42N8O5
|
1
|
1 |
IC50 = 18 nM
|
|
|
CP0413476
|
(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-(2-phenylphenyl)propanamide
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|
C31H37N5O5
|
1
|
1 |
IC50 = 19.8 nM
|
|
|
CP0488972
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-(2-phenylphenyl)propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C34H44N8O5
|
1
|
1 |
IC50 = 20.25 nM
|
|
|
CP0552003
|
2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetic acid
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|
C25H32N4O6
|
1
|
1 |
IC50 = 22.6 nM
|
|
|
CP0452579
|
3-(2-(3-tert-Butylphenyl)-5-((dimethylamino)methyl)-2H-1,2,4-triazol-3-yl)phenol
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|
C21H26N4O
|
1
|
1 |
IC50 = 28.8 nM
|
|
|
CP0545964
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-[4-(trifluoromethyl)phenyl]propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C29H39F3N8O5
|
1
|
1 |
IC50 = 39.2 nM
|
|
|
CP0561937
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C34H44N8O5
|
1
|
1 |
IC50 = 42.3 nM
|
|
|
CP0390376
|
3-(5-(3-tert-Butylphenyl)-3-((dimethylamino)methyl)-1H-1,2,4-triazol-1-yl)phenol
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|
C21H26N4O
|
1
|
1 |
IC50 = 48.9 nM
|
|
|
CP0548659
|
(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]-methylamino]-N-(2-amino-2-oxoethyl)-3-(2-ethenylphenyl)propanamide
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|
C28H37N5O5
|
1
|
1 |
IC50 = 59.4 nM
|
|
|
CP0563347
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-(2-amino-2-oxoethyl)-8-bromo-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
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|
C29H39BrN8O5
|
1
|
1 |
IC50 = 60.7 nM
|
|
|
CP0394278
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C29H42N8O6
|
1
|
1 |
IC50 = 70.2 nM
|
|
|
CP0373889
|
3-(2-(4-tert-Butylphenyl)-5-((dimethylamino)methyl)-2H-1,2,4-triazol-3-yl)phenol
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|
C21H26N4O
|
1
|
1 |
IC50 = 121 nM
|
|
|
CP0519987
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-(2-amino-2-oxoethyl)-3-oxo-4,5-dihydro-1H-benzo[i][2]benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C33H42N8O5
|
1
|
1 |
IC50 = 153 nM
|
|
|
CP0548657
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(3-ethenylphenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C30H42N8O5
|
1
|
1 |
IC50 = 165 nM
|
|
|
CP0541894
|
(2S)-2-amino-N-[(2R)-1-[[(4S)-2-(2-amino-2-oxoethyl)-3-oxo-4,5-dihydro-1H-benzo[i][2]benzazepin-4-yl]amino]-1-oxopropan-2-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
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|
C30H35N5O5
|
1
|
1 |
IC50 = 167 nM
|
|
|
CP0548658
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-(3-phenylphenyl)propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C34H44N8O5
|
1
|
1 |
IC50 = 268.8 nM
|
|
|
CP0390387
|
3-(3-((Dimethylamino)methyl)-5-(2,4-dimethylphenyl)-1H-1,2,4-triazol-1-yl)phenol
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|
C19H22N4O
|
1
|
1 |
IC50 = 273 nM
|
|
|
CP0475297
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-(4-thiophen-3-ylphenyl)propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C32H42N8O5S
|
1
|
1 |
IC50 = 309 nM
|
|
|
CP0394279
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4-chlorophenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C28H39ClN8O5
|
1
|
1 |
IC50 = 346 nM
|
|
|
CP0426440
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4-fluorophenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C28H39FN8O5
|
1
|
1 |
IC50 = 435 nM
|
|
|
CP0417239
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-[2-(2-methylprop-1-enyl)phenyl]-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C32H46N8O5
|
1
|
1 |
IC50 = 585 nM
|
|
|
CP0548661
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-(3-thiophen-3-ylphenyl)propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C32H42N8O5S
|
1
|
1 |
IC50 = 601 nM
|
|
|
CP0386948
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-(2-thiophen-3-ylphenyl)propan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C32H42N8O5S
|
1
|
1 |
IC50 = 625 nM
|
|
|
CP0557391
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(3S)-1-(2-amino-2-oxoethyl)-2-oxo-3,4-dihydroquinolin-3-yl]-5-(diaminomethylideneamino)pentanamide
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|
C28H38N8O5
|
1
|
1 |
IC50 = 630 nM
|
|
|
CP0475884
|
(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-(2-thiophen-3-ylphenyl)propanamide
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|
C29H35N5O5S
|
1
|
1 |
IC50 = 687 nM
|
|
|
CP0452580
|
(1-(3-tert-Butylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 = 1139 nM
|
|
|
CP0545984
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4-ethenylphenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C30H42N8O5
|
1
|
1 |
IC50 = 1415 nM
|
|
|
CP0043301
|
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide
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|
C26H35N5O6
|
1
|
1 |
IC50 = 1533 nM
|
|
|
CP0510367
|
(5-(3-tert-Butylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 = 2195 nM
|
|
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CP0373884
|
(5-(4-tert-Butylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 = 2307 nM
|
|
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CP0373269
|
(5-(2,4-Dimethylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C20H24N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0417784
|
(1-(4-tert-Butylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0514821
|
methyl (1S,9S,14E,15S,16R,19S)-14-ethylidene-2-methyl-18-oxa-2,12-diazahexacyclo[13.3.2.01,9.03,8.09,16.012,19]icosa-3,5,7-triene-16-carboxylate
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|
C22H26N2O3
|
1
|
1 |
IC50 = 95600 nM
|
|
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CP0050068
|
(1S,2S,13R,21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol
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|
C26H26N2O3
|
2
|
1 |
Ki = 0.19 nM
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|
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2 |
Ki = 1.82 nM
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CP0054764
|
2-[(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-7-yl]guanidine
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|
C27H29N5O3
|
2
|
1 |
Ki = 1.1 nM
|
|
|
2 |
Ki = 46.2 nM
|
|
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CP0722817
|
SID56463016
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|
C26H27ClN2O3
|
1
|
1 |
Ki = 2.63 nM
|
|
|
CP0096567
|
7-(2'-spiroindanyl)oxymorphone
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|
C25H25NO4
|
2
|
1 |
Ki = 4.1 nM
|
|
|
2 |
Ki = 46.6 nM
|
|
|
CP0041449
|
C18130
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|
C40H43N3O6
|
2
|
1 |
Ki = 5.2 nM
|
|
|
2 |
Ki = 41.5 nM
|
|
|
CP0854366
|
L4
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|
C58H78ClN7O10
|
1
|
1 |
Ki = 19.95 nM
|
|
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CP0497461
|
2-[2-[5-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]pentylamino]-2-oxoethoxy]-N-methylacetamide
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|
C34H49N5O9
|
1
|
1 |
Ki = 30.9 nM
|
|
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CP0048724
|
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
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|
C20H23NO4
|
2
|
1 |
Ki = 44.7 nM
|
|
|
2 |
Ki = 55.7 nM
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CP0449535
|
(1S,2S,13R,21R)-9-amino-22-(cyclopropylmethyl)-16-(2-phenylethoxy)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-2-ol
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|
C34H35N3O3
|
1
|
1 |
Ki = 91.2 nM
|
|
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CP0865937
|
L2
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|
C64H76ClN7O12
|
1
|
1 |
Ki = 204.17 nM
|
|
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CP0221707
|
1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminomethyl-(1,2,4-triazol-4-yl)}-3-phenol
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|
C21H26N4O
|
1
|
1 |
Ki = 460 nM
|
|
|
CP0048256
|
10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
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|
C17H19NO4
|
3
|
1 |
Ki = 610 nM
|
|
|
2 |
Ki = 724.44 nM
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|
|
3 |
Ki = 730 nM
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CP0134916
|
1-{3-[3-(tert-butyl) phenyl]-5-N,N-dimethylaminomethyl-(1,2,4-triazol-4-yl) }-3-phenol
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|
C21H26N4O
|
1
|
1 |
Ki = 2600 nM
|
|
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CP0890998
|
4-{[2,6-Dimethyl-4-(2-{[5-(2-methylcarbamoylmethoxy-acetylamino)-pentylcarbamoyl]-methoxy}-acetylamino)-phenyl]-piperidin-4-ylidene-methyl}-N,N-diethyl-benzamide hydrochloride
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|
C39H57ClN6O7
|
1
|
1 |
Ki = 2884.03 nM
|
|
|