| Compound ID |
Compound Name |
Compound Formula |
|
CP0488416
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(2-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C23H27ClN6O5
|
2
|
| 1 |
Kd = 12.59 nM
|
|
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| 2 |
Ki = 25.12 nM
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CP0495143
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-phenoxycyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C23H28N6O5
|
2
|
| 1 |
Kd = 14.79 nM
|
|
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| 2 |
Ki = 38.9 nM
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CP0488422
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(3-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C23H27ClN6O5
|
2
|
| 1 |
Kd = 17.38 nM
|
|
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| 2 |
Ki = 30.9 nM
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CP0488244
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(3-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C21H24ClN5O5
|
2
|
| 1 |
Kd = 23.44 nM
|
|
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| 2 |
Ki = 43.65 nM
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CP0494931
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-(3-methoxyphenoxy)cyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
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|
C24H30N6O6
|
2
|
| 1 |
Kd = 23.99 nM
|
|
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| 2 |
Ki = 141.25 nM
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CP0488425
|
(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(2-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C21H24ClN5O5
|
2
|
| 1 |
Kd = 26.3 nM
|
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| 2 |
Ki = 52.48 nM
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CP0488419
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(3-bromophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C21H24BrN5O5
|
2
|
| 1 |
Kd = 38.02 nM
|
|
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| 2 |
Ki = 114.82 nM
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CP0495164
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(4-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C23H27ClN6O5
|
2
|
| 1 |
Kd = 54.95 nM
|
|
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| 2 |
Ki = 83.18 nM
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CP0495148
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(2-chlorophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H29ClN6O5
|
2
|
| 1 |
Kd = 63.1 nM
|
|
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| 2 |
Ki = 141.25 nM
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CP0488424
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(3-chlorophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H29ClN6O5
|
2
|
| 1 |
Kd = 95.5 nM
|
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| 2 |
Ki = 125.89 nM
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CP0534813
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(4-tert-butylphenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C27H36N6O5
|
2
|
| 1 |
Kd = 112.2 nM
|
|
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| 2 |
Ki = 141.25 nM
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CP0488250
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(3-bromophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C23H27BrN6O5
|
2
|
| 1 |
Kd = 141.25 nM
|
|
|
| 2 |
Ki = 151.36 nM
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CP0546622
|
(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-[(2-chlorophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C22H26ClN5O5
|
2
|
| 1 |
Kd = 169.82 nM
|
|
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| 2 |
Ki = 275.42 nM
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CP0527804
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(1R,2R)-2-phenoxycyclopentyl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C21H25N5O5
|
2
|
| 1 |
Kd = 199.53 nM
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| 2 |
Ki = 251.19 nM
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CP0488415
|
(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-[(3-chlorophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C22H26ClN5O5
|
2
|
| 1 |
Kd = 208.93 nM
|
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| 2 |
Ki = 371.54 nM
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CP0488249
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(4-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C21H24ClN5O5
|
2
|
| 1 |
Kd = 263.03 nM
|
|
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| 2 |
Ki = 602.56 nM
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CP0488420
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(1R,2R)-2-(3-methoxyphenoxy)cyclopentyl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C22H27N5O6
|
2
|
| 1 |
Kd = 263.03 nM
|
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| 2 |
Ki = 275.42 nM
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CP0488246
|
(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(4-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H29BrN6O5
|
2
|
| 1 |
Kd = 275.42 nM
|
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| 2 |
Ki = 416.87 nM
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CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C12H16N6O4
|
2
|
| 1 |
Kd = 295.12 nM
|
|
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| 2 |
Ki = 416.87 nM
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CP0527802
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(1R,2R)-2-[(3-methoxyphenyl)methoxy]cyclopentyl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C23H29N5O6
|
2
|
| 1 |
Kd = 323.59 nM
|
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| 2 |
Ki = 281.84 nM
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CP0381926
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(1R,2R)-2-phenylmethoxycyclopentyl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C22H27N5O5
|
2
|
| 1 |
Kd = 398.11 nM
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| 2 |
Ki = 389.05 nM
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CP0488423
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(3-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H29BrN6O5
|
2
|
| 1 |
Kd = 416.87 nM
|
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| 2 |
Ki = 346.74 nM
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CP0488421
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-[(4-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C22H26BrN5O5
|
2
|
| 1 |
Kd = 575.44 nM
|
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| 2 |
Ki = 870.96 nM
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CP0488245
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-[(3-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C22H26BrN5O5
|
2
|
| 1 |
Kd = 676.08 nM
|
|
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| 2 |
Ki = 741.31 nM
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CP0495149
|
(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(4-tert-butylphenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C25H33N5O5
|
2
|
| 1 |
Kd = 676.08 nM
|
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| 2 |
Ki = 199.53 nM
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CP0495145
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-[(3-methoxyphenyl)methoxy]cyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
|
C25H32N6O6
|
2
|
| 1 |
Kd = 707.95 nM
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| 2 |
Ki = 776.25 nM
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CP0001102
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(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
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|
C10H13N5O4
|
2
|
| 1 |
Kd = 1949.84 nM
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| 2 |
Ki = 870.96 nM
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CP0058033
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1,3-dipropyl-8-cyclopentylxanthine
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|
C16H24N4O2
|
1
|
| 1 |
Ki = 1 nM
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CP0301653
|
8-(2,5-Dihydroxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
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|
C17H20N4O4
|
1
|
| 1 |
Ki = 7.46 nM
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CP0150055
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8-Cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione
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|
C13H18N4O2
|
1
|
| 1 |
Ki = 7.68 nM
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CP0069838
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(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester
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|
C26H26N6O4
|
1
|
| 1 |
Ki = 16.8 nM
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CP0281098
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8-(3,5-Dihydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C18H22N4O5
|
1
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| 1 |
Ki = 30.3 nM
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CP0277937
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8-(2,3-Dihydroxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
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|
C17H20N4O4
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1
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| 1 |
Ki = 39 nM
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CP0412151
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N-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenyl]acetamide
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|
C19H23N5O3
|
1
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| 1 |
Ki = 39.2 nM
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CP0083663
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8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C18H22N4O4
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1
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| 1 |
Ki = 97.7 nM
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CP0255221
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8-(2,4-Dihydroxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C17H20N4O4
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1
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| 1 |
Ki = 220 nM
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CP0200052
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1-Allyl-3-methyl-8-phenyl-3,7-dihydro-purine-2,6-dione
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|
C15H14N4O2
|
1
|
| 1 |
Ki = 302 nM
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CP0259712
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N-[4-(3,5-dimethylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C22H18N4OS
|
1
|
| 1 |
Ki = 333 nM
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CP0292429
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2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-3-hydroxyphenoxy]acetic acid
Show/Hide
|
C19H22N4O6
|
1
|
| 1 |
Ki = 757 nM
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CP0094874
|
1-Benzyl-3-methyl-3,7-dihydro-purine-2,6-dione
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|
C13H12N4O2
|
1
|
| 1 |
Ki = 1660 nM
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CP0367729
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7-(2-Chloro-ethyl)-8-phenyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
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|
C19H23ClN4O2
|
1
|
| 1 |
Ki = 1660 nM
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CP0442961
|
1-Butyl-3-ethyl-3,7-dihydro-purine-2,6-dione
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|
C11H16N4O2
|
1
|
| 1 |
Ki = 2170 nM
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CP0303870
|
1-Propyl-3,7-dihydro-purine-2,6-dione
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|
C8H10N4O2
|
1
|
| 1 |
Ki = 3310 nM
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CP0312454
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1-Cyclopentyl-3,7-dihydro-purine-2,6-dione
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|
C10H12N4O2
|
1
|
| 1 |
Ki = 5570 nM
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CP0290021
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3-Methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
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|
C9H8N4O2
|
1
|
| 1 |
Ki = 5830 nM
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CP0042654
|
1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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|
C7H8N4O2
|
1
|
| 1 |
Ki = 6920 nM
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CP0225943
|
1-Butyl-3,7-dihydro-purine-2,6-dione
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|
C9H12N4O2
|
1
|
| 1 |
Ki = 8890 nM
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CP0447816
|
1-Prop-2-ynyl-3,7-dihydro-purine-2,6-dione
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|
C8H6N4O2
|
1
|
| 1 |
Ki = 12700 nM
|
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CP0405406
|
7-(2-Chloro-ethyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
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|
C9H11ClN4O2
|
1
|
| 1 |
Ki = 15200 nM
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CP0193365
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7-(4-Chloro-butyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
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|
C11H15ClN4O2
|
1
|
| 1 |
Ki = 17700 nM
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CP0404084
|
7-(3-Chloro-propyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
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|
C10H13ClN4O2
|
1
|
| 1 |
Ki = 23600 nM
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CP0277227
|
1-Allyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C8H8N4O2
|
1
|
| 1 |
Ki = 24300 nM
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CP0099653
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3-Methyl-1-(3-phenyl-propyl)-3,7-dihydro-purine-2,6-dione
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|
C15H16N4O2
|
1
|
| 1 |
Ki = 24400 nM
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CP0150225
|
1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione
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|
C8H10N4O2
|
1
|
| 1 |
Ki = 24700 nM
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CP0300560
|
3-Methyl-1-phenethyl-3,7-dihydro-purine-2,6-dione
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|
C14H14N4O2
|
1
|
| 1 |
Ki = 27600 nM
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CP0299690
|
1-Phenethyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C13H12N4O2
|
1
|
| 1 |
Ki = 37600 nM
|
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