Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01430 , 3-oxo-5-alpha-steroid 4-dehydrogenase 1
 Protein Info 
Gene Name SRD5A1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P18405
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01430
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0043937
 Compound Info 
(17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one
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C23H36N2O2
  3
1
IC50 = 218 nM
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2
IC50 = 453 nM
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3
IC50 = 540 nM
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CP0452514
 Compound Info 
1-[(8S,9S,10R,13S,14S)-10,13-dimethyl-3-(2H-tetrazol-5-yl)-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
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C22H30N4O
  1
1
IC50 = 547 nM
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CP0845684
 Compound Info 
(10R,13S,17S)-4-Mercapto-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid tert-butylamide
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C24H37NO2S
  1
1
IC50 = 709 nM
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CP0509404
 Compound Info 
(10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid tert-butylamide
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C24H36BrNO2
  1
1
IC50 = 981 nM
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CP0704726
 Compound Info 
17-(1-Hydroxyimino-ethyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
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C21H31NO2
  1
1
IC50 = 1770 nM
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CP0829272
 Compound Info 
(10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-acetaldehyde oxime
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C21H31NO2
  1
1
IC50 = 2440 nM
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CP0900049
 Compound Info 
(10R,13S)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
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C19H26O2
  1
1
IC50 = 2700 nM
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CP0774469
 Compound Info 
17-(2-Hydroxyimino-propyl)-10,13-dimethyl-1,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,6-dione
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C22H31NO3
  1
1
IC50 = 2900 nM
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CP0403588
 Compound Info 
(10R,13S,17S)-4-Chloro-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid tert-butylamide
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C24H36ClNO2
  1
1
IC50 > 1000 nM
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CP0907037
 Compound Info 
(10R,13S,17S)-4-Hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid tert-butylamide
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C24H37NO3
  1
1
IC50 > 1000 nM
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