Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01179 , Beta-1 adrenergic receptor
Gene Name ADRB1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P08588
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01179
 
Compound ID Compound Name Compound Formula
CP0958800
(R)-5-(2-(4-(3-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
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C22H26Cl2N2O3
 1
1
EC50 = 0.6026 nM
   TI
   LI
   LO
   TS
CP0966209
(R)-5-(2-(4-(4-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C22H26Cl2N2O3
 1
1
EC50 = 0.8511 nM
   TI
   LI
   LO
   TS
CP0526866
6-hydroxy-8-[(1R)-1-hydroxy-2-[(2-methyl-4-phenylbutan-2-yl)amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C21H27ClN2O4
 1
1
EC50 = 1.23 nM
   TI
   LI
   LO
   TS
CP0068209
4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride
   Show/Hide
C11H17NO3
 3
1
EC50 = 1.259 nM
   TI
   LI
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   TS
2
EC50 = 3.162 nM
   TI
   LI
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3
EC50 = 1000 nM
   TI
   LI
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   TS
CP0542110
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(2-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C22H29ClN2O5
 1
1
EC50 = 1.413 nM
   TI
   LI
   LO
   TS
CP0065922
4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
   Show/Hide
C13H21NO3
 1
1
EC50 = 1.53 nM
   TI
   LI
   LO
   TS
CP0652587
SID50085961
   Show/Hide
C11H18ClNO3
 1
1
EC50 = 1.549 nM
   TI
   LI
   LO
   TS
CP0887725
8-hydroxy-5-(1-hydroxy-2-(4-(2-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O4
 1
1
EC50 = 1.549 nM
   TI
   LI
   LO
   TS
CP0954079
5-(2-(4-(2-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C22H26Cl2N2O3
 1
1
EC50 = 1.738 nM
   TI
   LI
   LO
   TS
CP0887728
8-hydroxy-5-((R)-1-hydroxy-2-((R)-4-(2-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O4
 1
1
EC50 = 1.862 nM
   TI
   LI
   LO
   TS
CP0958764
8-hydroxy-5-(1-hydroxy-2-(4-(2-methoxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C23H29ClN2O4
 1
1
EC50 = 2.042 nM
   TI
   LI
   LO
   TS
CP0951005
8-hydroxy-5-(1-hydroxy-2-(2-methyl-4-o-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C23H29ClN2O3
 1
1
EC50 = 2.138 nM
   TI
   LI
   LO
   TS
CP0943065
8-hydroxy-5-(1-hydroxy-2-(4-(3-hydroxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C21H25ClN2O4
 1
1
EC50 = 2.344 nM
   TI
   LI
   LO
   TS
CP0887723
8-hydroxy-5-(1-hydroxy-2-(4-(3-hydroxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O4
 1
1
EC50 = 2.399 nM
   TI
   LI
   LO
   TS
CP0958765
8-hydroxy-5-(1-hydroxy-2-(4-(3-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O4
 1
1
EC50 = 2.57 nM
   TI
   LI
   LO
   TS
CP0958798
8-hydroxy-5-(1-hydroxy-2-(2-methyl-4-m-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C23H29ClN2O3
 1
1
EC50 = 2.63 nM
   TI
   LI
   LO
   TS
CP0462135
1-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]-3-phenylurea
   Show/Hide
C26H28N4O3
 1
1
EC50 = 2.884 nM
   TI
   LI
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   TS
CP0887726
5-(2-(4-(3-fluorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C21H24ClFN2O3
 1
1
EC50 = 3.09 nM
   TI
   LI
   LO
   TS
CP0958106
5-(2-(4-(4-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C22H26Cl2N2O3
 1
1
EC50 = 3.09 nM
   TI
   LI
   LO
   TS
CP0526865
6-hydroxy-8-[1-hydroxy-2-[[4-(2-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C22H29ClN2O5
 1
1
EC50 = 3.89 nM
   TI
   LI
   LO
   TS
CP0944327
8-hydroxy-5-(1-hydroxy-2-(4-m-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O3
 1
1
EC50 = 4.074 nM
   TI
   LI
   LO
   TS
CP0526867
6-hydroxy-8-[1-hydroxy-2-[[4-(3-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C21H27ClN2O5
 1
1
EC50 = 4.169 nM
   TI
   LI
   LO
   TS
CP0887724
5-(2-(3-(3,5-difluorophenyl)propylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C20H21ClF2N2O3
 1
1
EC50 = 4.266 nM
   TI
   LI
   LO
   TS
CP0868554
5-(2-(3-(3-fluorophenyl)propylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C20H22ClFN2O3
 1
1
EC50 = 4.467 nM
   TI
   LI
   LO
   TS
CP0954078
8-hydroxy-5-(1-hydroxy-2-(4-(4-hydroxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C21H25ClN2O4
 1
1
EC50 = 4.467 nM
   TI
   LI
   LO
   TS
CP0956216
5-(2-(4-(3-chlorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C21H24Cl2N2O3
 1
1
EC50 = 4.467 nM
   TI
   LI
   LO
   TS
CP0962608
5-(2-(4-(2-chlorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C21H24Cl2N2O3
 1
1
EC50 = 4.571 nM
   TI
   LI
   LO
   TS
CP0435689
8-hydroxy-5-[1-hydroxy-2-[3-(2-hydroxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C20H22N2O4
 1
1
EC50 = 5.012 nM
   TI
   LI
   LO
   TS
CP0468963
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(4-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C21H27ClN2O5
 1
1
EC50 = 5.37 nM
   TI
   LI
   LO
   TS
CP0423781
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(3-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C22H29ClN2O5
 1
1
EC50 = 5.623 nM
   TI
   LI
   LO
   TS
CP0479007
8-hydroxy-5-[(1R)-1-hydroxy-2-[(2-methyl-4,4-diphenylbutan-2-yl)amino]ethyl]-1H-quinolin-2-one
   Show/Hide
C28H30N2O3
 1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
CP0960790
5-(2-(4-(4-chlorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C21H24Cl2N2O3
 1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
CP0455839
5-[(1R)-2-[[4,4-bis(4-fluorophenyl)-2-methylbutan-2-yl]amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C28H28F2N2O3
 1
1
EC50 = 6.761 nM
   TI
   LI
   LO
   TS
CP0868555
8-hydroxy-5-(1-hydroxy-2-(4-o-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O3
 1
1
EC50 = 6.761 nM
   TI
   LI
   LO
   TS
CP0479011
8-hydroxy-5-[1-hydroxy-2-[3-(3-methoxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C21H24N2O4
 1
1
EC50 = 7.413 nM
   TI
   LI
   LO
   TS
CP0868557
8-hydroxy-5-(1-hydroxy-2-(4-(3-methoxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C23H29ClN2O4
 1
1
EC50 = 7.586 nM
   TI
   LI
   LO
   TS
CP0559126
N-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]-2-phenylacetamide
   Show/Hide
C27H29N3O3
 1
1
EC50 = 7.643 nM
   TI
   LI
   LO
   TS
CP0943067
8-hydroxy-5-(1-hydroxy-2-(4-(4-methoxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C23H29ClN2O4
 1
1
EC50 = 7.762 nM
   TI
   LI
   LO
   TS
CP0473096
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(4-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C22H29ClN2O5
 1
1
EC50 = 8.128 nM
   TI
   LI
   LO
   TS
CP0539325
8-hydroxy-5-[1-hydroxy-2-(3-phenylpropylamino)ethyl]-1H-quinolin-2-one
   Show/Hide
C20H22N2O3
 1
1
EC50 = 9.772 nM
   TI
   LI
   LO
   TS
CP0951004
8-hydroxy-5-(1-hydroxy-2-(4-p-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O3
 1
1
EC50 = 10.47 nM
   TI
   LI
   LO
   TS
CP0956215
5-(2-(4-(4-fluorophenyl)butan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C21H24ClFN2O3
 1
1
EC50 = 10.47 nM
   TI
   LI
   LO
   TS
CP0958799
5-(2-(4-(3-chlorophenyl)-2-methylbutan-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C22H26Cl2N2O3
 1
1
EC50 = 10.47 nM
   TI
   LI
   LO
   TS
CP0455840
8-hydroxy-5-[1-hydroxy-2-[3-(2-methoxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C21H24N2O4
 1
1
EC50 = 11.22 nM
   TI
   LI
   LO
   TS
CP0525486
6-hydroxy-8-[1-hydroxy-2-[[4-(3-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C22H29ClN2O5
 1
1
EC50 = 12.3 nM
   TI
   LI
   LO
   TS
CP0435688
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-3,5,5-trimethylhexanamide
   Show/Hide
C29H39N3O4
 1
1
EC50 = 13.49 nM
   TI
   LI
   LO
   TS
CP0868573
8-hydroxy-5-(1-hydroxy-2-(3-m-tolylpropylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C21H25ClN2O3
 1
1
EC50 = 14.45 nM
   TI
   LI
   LO
   TS
CP0423699
N-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]benzenesulfonamide
   Show/Hide
C25H27N3O4S
 1
1
EC50 = 14.79 nM
   TI
   LI
   LO
   TS
CP0468962
6-hydroxy-8-[1-hydroxy-2-[(2-methyl-4-phenylbutan-2-yl)amino]ethyl]-4H-1,4-benzoxazin-3-one
   Show/Hide
C21H26N2O4
 1
1
EC50 = 14.79 nM
   TI
   LI
   LO
   TS
CP0436152
8-hydroxy-5-[1-hydroxy-2-(3-naphthalen-2-ylpropylamino)ethyl]-1H-quinolin-2-one
   Show/Hide
C24H24N2O3
 1
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
CP0534398
8-hydroxy-5-[1-hydroxy-2-[3-(4-phenylphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C26H26N2O3
 1
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
CP0967149
5-(2-(3-(4-fluorophenyl)propylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one hydrochloride
   Show/Hide
C20H22ClFN2O3
 1
1
EC50 = 16.22 nM
   TI
   LI
   LO
   TS
CP0959115
8-hydroxy-5-(1-hydroxy-2-(3-o-tolylpropylamino)ethyl)quinolin-2(1H)-one Hydrochloride
   Show/Hide
C21H25ClN2O3
 1
1
EC50 = 16.98 nM
   TI
   LI
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   TS
CP0534396
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-2-methylpropanamide
   Show/Hide
C24H29N3O4
 1
1
EC50 = 22.39 nM
   TI
   LI
   LO
   TS
CP0930983
8-hydroxy-5-(1-hydroxy-2-(4-(4-hydroxyphenyl)-2-methylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O4
 1
1
EC50 = 22.39 nM
   TI
   LI
   LO
   TS
CP0964080
8-hydroxy-5-(1-hydroxy-2-(2-methyl-4-p-tolylbutan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C23H29ClN2O3
 1
1
EC50 = 24.55 nM
   TI
   LI
   LO
   TS
CP0420335
BI 1744 CL
   Show/Hide
C21H27ClN2O5
 1
1
EC50 = 27.54 nM
   TI
   LI
   LO
   TS
CP0530797
6-hydroxy-8-[1-hydroxy-2-[[4-(4-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C21H27ClN2O5
 1
1
EC50 = 28.84 nM
   TI
   LI
   LO
   TS
CP0887727
8-hydroxy-5-(1-hydroxy-2-(3-p-tolylpropylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C21H25ClN2O3
 1
1
EC50 = 30.2 nM
   TI
   LI
   LO
   TS
CP0943066
8-hydroxy-5-(1-hydroxy-2-(4-(3,4,5-trimethoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C24H31ClN2O6
 1
1
EC50 = 35.48 nM
   TI
   LI
   LO
   TS
CP0467734
N-[4-[2-[[(2S)-2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]benzamide
   Show/Hide
C26H27N3O3
 1
1
EC50 = 35.98 nM
   TI
   LI
   LO
   TS
CP0534393
8-hydroxy-5-[1-hydroxy-2-[3-(4-hydroxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C20H22N2O4
 1
1
EC50 = 36.31 nM
   TI
   LI
   LO
   TS
CP0423780
6-hydroxy-8-[(1R)-1-hydroxy-2-[[4-(3-hydroxyphenyl)-2-methylbutan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride
   Show/Hide
C21H27ClN2O5
 1
1
EC50 = 36.31 nM
   TI
   LI
   LO
   TS
CP0392554
N-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]-2-phenylacetamide
   Show/Hide
C27H32N2O3
 1
1
EC50 = 36.81 nM
   TI
   LI
   LO
   TS
CP0558032
8-hydroxy-5-[1-hydroxy-2-[3-(4-methoxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C21H24N2O4
 1
1
EC50 = 43.65 nM
   TI
   LI
   LO
   TS
CP0965873
8-hydroxy-5-(1-hydroxy-2-(4-(4-methoxyphenyl)butan-2-ylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C22H27ClN2O4
 1
1
EC50 = 44.67 nM
   TI
   LI
   LO
   TS
CP0537196
8-hydroxy-5-[1-hydroxy-2-(2-phenoxyethylamino)ethyl]-1H-quinolin-2-one
   Show/Hide
C19H20N2O4
 1
1
EC50 = 72.44 nM
   TI
   LI
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   TS
CP0957369
8-hydroxy-5-(1-hydroxy-2-(3-(3-(trifluoromethyl)phenyl)propylamino)ethyl)quinolin-2(1H)-one hydrochloride
   Show/Hide
C21H22ClF3N2O3
 1
1
EC50 = 77.62 nM
   TI
   LI
   LO
   TS
CP0455838
8-hydroxy-5-[1-hydroxy-2-(4-phenylbutylamino)ethyl]-1H-quinolin-2-one
   Show/Hide
C21H24N2O3
 1
1
EC50 = 87.1 nM
   TI
   LI
   LO
   TS
CP0451157
BI 1744
   Show/Hide
C21H26N2O5
 1
1
EC50 = 123.03 nM
   TI
   LI
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   TS
CP0427807
N-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]benzamide
   Show/Hide
C26H30N2O3
 1
1
EC50 = 123.7 nM
   TI
   LI
   LO
   TS
CP0436151
8-hydroxy-5-[1-hydroxy-2-[3-(3-hydroxyphenyl)propylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C20H22N2O4
 1
1
EC50 = 218.78 nM
   TI
   LI
   LO
   TS
CP0471977
N-[[3-[(2S)-2-hydroxy-3-[2-[4-(phenylsulfamoylamino)phenyl]ethylamino]propoxy]phenyl]methyl]acetamide
   Show/Hide
C26H32N4O5S
 1
1
EC50 = 223.6 nM
   TI
   LI
   LO
   TS
CP0557256
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]benzamide
   Show/Hide
C27H27N3O4
 1
1
EC50 = 239.88 nM
   TI
   LI
   LO
   TS
CP0427808
N-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]benzenesulfonamide
   Show/Hide
C25H30N2O4S
 1
1
EC50 = 298.8 nM
   TI
   LI
   LO
   TS
CP0065062
1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol
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C25H37NO4
 3
1
EC50 = 316.23 nM
   TI
   LI
   LO
   TS
2
EC50 = 371.54 nM
   TI
   LI
   LO
   TS
3
EC50 = 1230.27 nM
   TI
   LI
   LO
   TS
CP0467735
1-[4-[2-[[(2S)-3-(2-ethylphenoxy)-2-hydroxypropyl]amino]ethyl]phenyl]-3-phenylthiourea
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C26H31N3O2S
 1
1
EC50 = 426.2 nM
   TI
   LI
   LO
   TS
CP0459152
8-hydroxy-5-[2-hydroxy-1-[2-(3-methoxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
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C20H22N2O4
 1
1
EC50 = 630.96 nM
   TI
   LI
   LO
   TS
CP0471845
8-hydroxy-5-[2-hydroxy-1-(3-phenylpropylamino)ethyl]-1H-quinolin-2-one
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C20H22N2O3
 1
1
EC50 = 831.76 nM
   TI
   LI
   LO
   TS
CP0514105
8-hydroxy-5-[2-hydroxy-1-(2-phenylethylamino)ethyl]-1H-quinolin-2-one
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C19H20N2O3
 1
1
EC50 = 831.76 nM
   TI
   LI
   LO
   TS
CP0440999
N-[[3-[(2S)-3-[2-[4-(benzenesulfonamido)phenyl]ethylamino]-2-hydroxypropoxy]phenyl]methyl]acetamide
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C26H31N3O5S
 1
1
EC50 = 889 nM
   TI
   LI
   LO
   TS
CP0479009
N-[4-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-2-methylpropanamide
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C24H29N3O4
 1
1
EC50 = 1445.44 nM
   TI
   LI
   LO
   TS
CP0389100
5-[1-[2-(4-chlorophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
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C19H19ClN2O3
 1
1
EC50 = 1584.89 nM
   TI
   LI
   LO
   TS
CP0537197
N-[3-[3-[[2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]propyl]phenyl]-4-methylpentanamide
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C26H33N3O4
 1
1
EC50 = 1949.84 nM
   TI
   LI
   LO
   TS
CP0459150
5-[1-[2-(3-chlorophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
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C19H19ClN2O3
 1
1
EC50 = 3162.28 nM
   TI
   LI
   LO
   TS
CP0467736
N-[4-[2-[[(2S)-3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]ethyl]phenyl]-2-phenylacetamide
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C28H33N3O4
 1
1
EC50 = 6204 nM
   TI
   LI
   LO
   TS
CP0392878
8-hydroxy-5-[2-hydroxy-1-[6-(4-phenylbutoxy)hexylamino]ethyl]-1H-quinolin-2-one
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C27H36N2O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0392879
8-hydroxy-5-[2-hydroxy-1-[2-(2-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
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C19H20N2O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0392883
8-hydroxy-5-[2-hydroxy-1-[(2-methyl-1-phenylpropan-2-yl)amino]ethyl]-1H-quinolin-2-one
   Show/Hide
C21H24N2O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0432458
5-[1-[2-(2-chlorophenyl)ethylamino]-2-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C19H19ClN2O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0432459
8-hydroxy-5-[2-hydroxy-1-[2-(4-hydroxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C19H20N2O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0432469
8-hydroxy-5-[2-hydroxy-1-[2-(2-methoxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
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C20H22N2O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0473783
8-hydroxy-5-[2-hydroxy-1-[2-(4-methoxyphenyl)ethylamino]ethyl]-1H-quinolin-2-one
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C20H22N2O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0508401
8-hydroxy-5-[2-hydroxy-1-(4-phenylbutylamino)ethyl]-1H-quinolin-2-one
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C21H24N2O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0534394
8-hydroxy-5-[(1R)-1-hydroxy-2-[(2-methyl-4-phenylbutan-2-yl)amino]ethyl]-1H-quinolin-2-one
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C22H26N2O3
 1
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0958102
8-hydroxy-5-(1-hydroxy-2-(3-(3,4,5-trimethoxyphenyl)propylamino)ethyl)quinolin-2(1H)-one hydrochloride
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C23H29ClN2O6
 1
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0471844
N-[[3-[(2S)-2-hydroxy-3-[2-[4-(phenylcarbamoylamino)phenyl]ethylamino]propoxy]phenyl]methyl]acetamide
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C27H32N4O4
 1
1
EC50 = 12700 nM
   TI
   LI
   LO
   TS
CP0462134
N-[4-[2-[[(2S)-3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]ethyl]phenyl]benzamide
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C27H31N3O4
 1
1
EC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0550313
2-(4-amino-3-bromo-5-fluorophenyl)-2-(3-ethoxypropylamino)ethanol;hydrochloride
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C13H21BrClFN2O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0568229
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(butylamino)ethanol;hydrochloride
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C13H19BrClF3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0568301
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol;hydrochloride
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C13H19BrClF3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0568302
2-(4-amino-3-bromo-5-fluorophenyl)-2-(tert-butylamino)ethanol;hydrochloride
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C12H19BrClFN2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569182
2-amino-3-bromo-5-[1-(3-ethoxypropylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
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C14H21BrClN3O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569396
2-(4-amino-3-bromo-5-fluorophenyl)-2-(butylamino)ethanol;hydrochloride
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C12H19BrClFN2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0569397
2-(4-amino-3-bromo-5-fluorophenyl)-2-[(4-fluorophenyl)methylamino]ethanol;hydrochloride
   Show/Hide
C15H16BrClF2N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0570404
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(butylamino)ethanol;hydrochloride
   Show/Hide
C13H19Cl2F3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0570405
2-(4-amino-3-bromo-5-fluorophenyl)-2-(propan-2-ylamino)ethanol;hydrochloride
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C11H17BrClFN2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0570407
2-amino-3-bromo-5-[1-(butylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
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C13H19BrClN3O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0574569
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(3-ethoxypropylamino)ethanol;hydrochloride
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C14H21Cl2F3N2O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0576023
2-amino-3-bromo-5-[1-(cyclopentylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
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C14H19BrClN3O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0578582
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[(2-methyl-1-phenylpropan-2-yl)amino]ethanol;hydrochloride
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C19H23Cl2F3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0578584
2-amino-3-bromo-5-[1-(tert-butylamino)-2-hydroxyethyl]benzonitrile;hydrochloride
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C13H19BrClN3O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579205
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(3-ethoxypropylamino)ethanol;hydrochloride
   Show/Hide
C14H21BrClF3N2O2
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579213
2-(4-amino-3-bromo-5-fluorophenyl)-2-(cyclopentylamino)ethanol;hydrochloride
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C13H19BrClFN2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579214
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(cyclopentylamino)ethanol;hydrochloride
   Show/Hide
C14H19Cl2F3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0579365
2-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-2-(cyclopentylamino)ethanol;hydrochloride
   Show/Hide
C14H19BrClF3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0970203
2-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol hydrochloride
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C13H19Cl2F3N2O
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0435169
(2S)-1-[2-[3-[4-[[[1-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]propyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C36H55N9O4
 2
1
IC50 = 4.677 nM
   TI
   LI
   LO
   TS
2
Ki = 1.096 nM
   TI
   LI
   LO
   TS
CP0552468
1,3-bis[5-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]pentyl]urea
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C35H58N4O5
 1
1
IC50 = 5.623 nM
   TI
   LI
   LO
   TS
CP0489921
(2S)-1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
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C15H23NO2
 2
1
IC50 = 5.888 nM
   TI
   LI
   LO
   TS
2
Ki = 1.445 nM
   TI
   LI
   LO
   TS
CP0540412
(2S)-1-[2-[10-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]decyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
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C34H56N2O4
 2
1
IC50 = 11.22 nM
   TI
   LI
   LO
   TS
2
Ki = 1.82 nM
   TI
   LI
   LO
   TS
CP0062567
ALPRENOLOL,(+)
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C15H23NO2
 2
1
IC50 = 13.8 nM
   TI
   LI
   LO
   TS
2
Ki = 2.818 nM
   TI
   LI
   LO
   TS
CP0476339
(2S)-1-[2-[12-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]dodecyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C36H60N2O4
 2
1
IC50 = 13.8 nM
   TI
   LI
   LO
   TS
2
Ki = 1.259 nM
   TI
   LI
   LO
   TS
CP0535807
1,3-bis[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butyl]urea
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C33H54N4O5
 2
1
IC50 = 14.45 nM
   TI
   LI
   LO
   TS
2
Ki = 3.981 nM
   TI
   LI
   LO
   TS
CP0435168
(2S)-1-[2-[2-[4-[[[1-[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C34H51N9O4
 2
1
IC50 = 19.5 nM
   TI
   LI
   LO
   TS
2
Ki = 2.884 nM
   TI
   LI
   LO
   TS
CP0476338
(2S)-1-[2-[8-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]octyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
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C32H52N2O4
 2
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
2
Ki = 4.169 nM
   TI
   LI
   LO
   TS
CP0431930
4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]ethyl]butanamide
   Show/Hide
C34H54N4O6
 2
1
IC50 = 26.3 nM
   TI
   LI
   LO
   TS
2
Ki = 8.913 nM
   TI
   LI
   LO
   TS
CP0476337
(2S)-1-[2-[6-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]hexyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
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C30H48N2O4
 2
1
IC50 = 27.54 nM
   TI
   LI
   LO
   TS
2
Ki = 6.457 nM
   TI
   LI
   LO
   TS
CP0508127
4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[3-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]propyl]butanamide
   Show/Hide
C35H56N4O6
 1
1
IC50 = 28.18 nM
   TI
   LI
   LO
   TS
CP0541127
(2S)-1-[2-[2-[2-[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenoxy]ethoxy]ethoxy]ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C30H48N2O8
 1
1
IC50 = 97.72 nM
   TI
   LI
   LO
   TS
CP0440669
1,3-bis[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethyl]urea
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C29H46N4O5
 2
1
IC50 = 125.89 nM
   TI
   LI
   LO
   TS
2
Ki = 19.5 nM
   TI
   LI
   LO
   TS
CP0554722
4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[4-[4-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]butyl]butanamide
   Show/Hide
C36H58N4O6
 1
1
IC50 = 181.97 nM
   TI
   LI
   LO
   TS
CP0087906
2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
   Show/Hide
C14H22N2O3
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0113242
(2S)-1-[2-[2-[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenoxy]ethoxy]ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C28H44N2O7
 1
1
IC50 = 234.42 nM
   TI
   LI
   LO
   TS
CP0446703
1,3-bis[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propyl]urea
   Show/Hide
C31H50N4O5
 2
1
IC50 = 371.54 nM
   TI
   LI
   LO
   TS
2
Ki = 44.67 nM
   TI
   LI
   LO
   TS
CP0304390
(2R)-1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
   Show/Hide
C15H23NO2
 2
1
IC50 = 436.52 nM
   TI
   LI
   LO
   TS
2
Ki = 64.57 nM
   TI
   LI
   LO
   TS
CP0446702
(2S)-1-[2-[[4-[[[1-[[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]methyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]methyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C32H47N9O4
 2
1
IC50 = 489.78 nM
   TI
   LI
   LO
   TS
2
Ki = 83.18 nM
   TI
   LI
   LO
   TS
CP0535826
3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[3-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoylamino]propyl]propanamide
   Show/Hide
C33H52N4O6
 1
1
IC50 = 1778.28 nM
   TI
   LI
   LO
   TS
CP0431928
3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[3-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoylamino]ethyl]propanamide
   Show/Hide
C32H50N4O6
 2
1
IC50 = 2041.74 nM
   TI
   LI
   LO
   TS
2
Ki = 269.15 nM
   TI
   LI
   LO
   TS
CP0435167
(2S)-1-[2-[4-[[[1-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]triazol-4-yl]methylamino]methyl]triazol-1-yl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
   Show/Hide
C30H43N9O4
 2
1
IC50 = 3630.78 nM
   TI
   LI
   LO
   TS
2
Ki = 478.63 nM
   TI
   LI
   LO
   TS
CP0535827
4-[2-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[4-[2-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanoylamino]ethyl]butanamide
   Show/Hide
C34H54N4O6
 1
1
IC50 = 4466.84 nM
   TI
   LI
   LO
   TS
CP0795225
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
   Show/Hide
C19H16N2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0435173
2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-N-[2-[[2-[2-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetyl]amino]ethyl]acetamide
   Show/Hide
C30H46N4O6
 2
1
IC50 = 10964.78 nM
   TI
   LI
   LO
   TS
2
Ki = 2570.4 nM
   TI
   LI
   LO
   TS
CP0069240
4-(piperazin-1-yl)-1H-indole
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C12H15N3
 1
1
Ki = 67.61 nM
   TI
   LI
   LO
   TS
CP0851569
1-(3,5-dichlorophenyl)piperazine
   Show/Hide
C10H12Cl2N2
 1
1
Ki = 85.11 nM
   TI
   LI
   LO
   TS
CP0364794
1-(2,3-dichlorophenyl)piperazine
   Show/Hide
C10H12Cl2N2
 1
1
Ki = 107.15 nM
   TI
   LI
   LO
   TS
CP0887116
2-Methylsulfanyl-4-piperazin-1-yl-6,7,8,9-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine
   Show/Hide
C15H20N4S2
 1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0967002
1-(3,4-dichlorophenyl)piperazine
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C10H12Cl2N2
 1
1
Ki = 213.8 nM
   TI
   LI
   LO
   TS
CP0184743
4-methyl-2-piperazin-1-ylquinoline
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C14H17N3
 1
1
Ki = 223.87 nM
   TI
   LI
   LO
   TS
CP0928989
2-(piperazin-1-yl)-8-(thiophen-2-yl)quinoline
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C17H17N3S
 1
1
Ki = 251.19 nM
   TI
   LI
   LO
   TS
CP0938166
1-(2,3-dimethylphenyl)piperazine
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C12H18N2
 1
1
Ki = 537.03 nM
   TI
   LI
   LO
   TS
CP0409298
5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7.4.0.0?⁷]trideca1(9),2(7),3,5tetraene (Inh 5)
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C16H22N4S
 1
1
Ki = 676.08 nM
   TI
   LI
   LO
   TS
CP0912457
1-(3,4-dimethylphenyl)piperazine
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C12H18N2
 1
1
Ki = 741.31 nM
   TI
   LI
   LO
   TS
CP0851568
1-(3,5-bis(trifluoromethyl)phenyl)piperazine
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C12H12F6N2
 1
1
Ki = 1258.93 nM
   TI
   LI
   LO
   TS
CP0200323
1-Phenyl-piperazine
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C10H14N2
 1
1
Ki = 1348.96 nM
   TI
   LI
   LO
   TS
CP0389867
2-methyl-4-piperazin-1-ylquinoline
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C14H17N3
 1
1
Ki = 1584.89 nM
   TI
   LI
   LO
   TS
CP0926771
1-(3,5-dimethoxyphenyl)piperazine
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C12H18N2O2
 1
1
Ki = 1584.89 nM
   TI
   LI
   LO
   TS
CP0931078
1-(4-(trifluoromethyl)pyridin-2-yl)piperazine
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C10H12F3N3
 1
1
Ki = 2344.23 nM
   TI
   LI
   LO
   TS
CP0868538
2-(piperazin-1-yl)-4-(trifluoromethyl)pyrimidine
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C9H11F3N4
 1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
CP0006029
2-(piperazin-1-yl)quinoline
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C13H15N3
 1
1
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CP0116478
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C24H30N2O
 1
1
Ki = 10232.93 nM
   TI
   LI
   LO
   TS
CP0232093
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C22H27N3O
 1
1
Ki = 32359.37 nM
   TI
   LI
   LO
   TS
CP0232092
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C21H32N2O
 1
1
Ki = 47863.01 nM
   TI
   LI
   LO
   TS