Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ALPRENOLOL,(+)
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 PubChem ID
CID: 2119
SID: 15044941
Canonical SMILES
CC(C)NCC(O)COc1ccccc1CC=C
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Compound Formula C15H23NO2
Compound Structure
Protein Name
 Protein Info 
Beta-1 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P08588
Gene Name
ADRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
Kd = 4.266 nM
   TI
   LI
   LO
   TS
2
Kd = 11.22 nM
   TI
   LI
   LO
   TS
3
Kd = 177.83 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 13.8 nM
   TI
   LI
   LO
   TS
2
Ki = 2.818 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.88 nM