| Compound ID |
Compound Name |
Compound Formula |
|
CP0093593
|
US8940748, 34
Show/Hide
|
C17H17ClFN5O3S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0097529
|
N-[3-[(4aR,7aS)-2-amino-4a,5,6,7-tetrahydro-4H-cyclopenta[d][1,3]thiazin-7a-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide
Show/Hide
|
C19H18F2N4OS
|
1
|
| 1 |
IC50 = 17.8 nM
|
|
|
|
CP0124822
|
US9315520, 7
Show/Hide
|
C17H18ClN5O2S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0551183
|
(4S)-3'-(3,6-dihydro-2H-pyran-5-yl)-1'-fluoro-7'-(2-fluoropyridin-3-yl)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-c]pyridine]-2-amine
Show/Hide
|
C24H18F2N4O3
|
1
|
| 1 |
IC50 = 55.7 nM
|
|
|
|
CP0097508
|
US9315520, 45
Show/Hide
|
C19H21F2N5O3S2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0097523
|
US9315520, 1
Show/Hide
|
C18H19F2N5O3S2
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0248620
|
N-[3-[(1S,5S,6S)-3-amino-1-(methoxymethyl)-5-methyl-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4,5-difluorophenyl]-5-prop-2-ynoxypyrazine-2-carboxamide
Show/Hide
|
C22H21F2N5O3S
|
1
|
| 1 |
IC50 = 569 nM
|
|
|
|
CP0234609
|
N-[3-[(1S,5S,6S)-3-amino-1-(difluoromethyl)-5-methyl-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4,5-difluorophenyl]-5-prop-2-ynoxypyrazine-2-carboxamide
Show/Hide
|
C21H17F4N5O2S
|
1
|
| 1 |
IC50 = 1290 nM
|
|
|
|
CP0389197
|
CHEMBL4084381
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0485752
|
CHEMBL4072118
Show/Hide
|
C24H24ClN3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0517966
|
CHEMBL4100832
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0852591
|
{3-((1r,1'R,4R)-2''-Amino-4-methoxy-3'H,5''H-dispiro-[cyclohexane-1,2'-indene-1',4''-oxazol]-6'-yl-5'',5''-d2)-5-chlorobenzonitrile}
Show/Hide
|
C24H24ClN3O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0085955
|
CHEMBL4097477
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 443 nM
|
|
|
|
CP0265376
|
N-[3-[(5R)-3-amino-5-methyl-9-oxa-2-thia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluorophenyl]-5-(fluoromethoxy)pyrazine-2-carboxamide
Show/Hide
|
C21H23F2N5O3S
|
1
|
| 1 |
Ki = 479 nM
|
|
|
|
CP0485736
|
CHEMBL4093123
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 710 nM
|
|
|
|
CP0229888
|
CHEMBL4070299
Show/Hide
|
C22H26N4O2
|
1
|
| 1 |
Ki = 817 nM
|
|
|
|
CP0470883
|
CHEMBL4085364
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 1011 nM
|
|
|
|
CP0229887
|
CHEMBL4103296
Show/Hide
|
C22H26N4O2
|
1
|
| 1 |
Ki = 1299 nM
|
|
|
|
CP0470882
|
CHEMBL4074071
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 1478 nM
|
|
|
|
CP0198194
|
N-[3-[(5R)-3-amino-5-methyl-9,9-dioxo-2,9lambda6-dithia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluorophenyl]-5-(fluoromethoxy)pyrazine-2-carboxamide
Show/Hide
|
C21H23F2N5O4S2
|
1
|
| 1 |
Ki = 1740 nM
|
|
|
|
CP0075806
|
N-[3-[(5R)-3-amino-9,9-difluoro-5-methyl-2-thia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluorophenyl]-5-(fluoromethoxy)pyrazine-2-carboxamide
Show/Hide
|
C22H23F4N5O2S
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0331641
|
CHEMBL4067413
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 2022 nM
|
|
|
|
CP0517965
|
CHEMBL4065448
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
Ki = 2077 nM
|
|
|
|
CP0471595
|
CHEMBL4092875
Show/Hide
|
C24H24ClN3O2
|
1
|
| 1 |
Ki = 2193 nM
|
|
|
