Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01055 , Serine/threonine-protein kinase PLK2
 Protein Info 
Gene Name PLK2
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q9NYY3
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01055
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0021461
 Compound Info 
(7R)-7-ethyl-2-[2-(4-fluorophenyl)imidazol-1-yl]-5-methyl-8-(1-methylpyrazol-3-yl)-7H-pteridin-6-one
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C22H21FN8O
  1
1
IC50 = 480 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0248815
 Compound Info 
7-ethyl-2-[2-(4-fluorophenyl)imidazol-1-yl]-5-methyl-8-(1H-pyrazol-5-yl)-7H-pteridin-6-one
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C21H19FN8O
  1
1
IC50 = 740 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0261084
 Compound Info 
(7R)-7-ethyl-2-[2-(4-fluorophenyl)imidazol-1-yl]-5-methyl-8-(1-methylpyrazol-4-yl)-7H-pteridin-6-one
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C22H21FN8O
  1
1
IC50 = 780 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0088101
 Compound Info 
(7R)-7-ethyl-2-[2-(4-fluorophenyl)imidazol-1-yl]-5-methyl-8-(1H-pyrazol-4-yl)-7H-pteridin-6-one
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C21H19FN8O
  1
1
IC50 = 1870 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0120617
 Compound Info 
(7R)-7-ethyl-2-[2-(4-fluorophenyl)imidazol-1-yl]-5-methyl-8-[(3S)-oxolan-3-yl]-7H-pteridin-6-one
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C22H23FN6O2
  1
1
IC50 = 2050 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0220986
 Compound Info 
(7R)-7-ethyl-2-[2-(4-fluorophenyl)imidazol-1-yl]-5-methyl-8-(3,3,3-trifluoropropyl)-7H-pteridin-6-one
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C21H20F4N6O
  1
1
IC50 = 2560 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0108841
 Compound Info 
(7R)-7-ethyl-5-methyl-8-(oxan-4-yl)-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one
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C20H23N7O2S
  1
1
IC50 = 2990 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0056992
 Compound Info 
(7R)-7-ethyl-5-methyl-8-[(3S)-oxolan-3-yl]-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one
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C19H21N7O2S
  1
1
IC50 = 3190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0911900
 Compound Info 
rac-7-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-8-(pyrimidin-5-yl)-7,8-dihydropteridin-6(5H)-one
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C22H20N8O
  1
1
IC50 = 3870 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0220983
 Compound Info 
(7R)-7-ethyl-5-methyl-8-(1H-pyrazol-4-yl)-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one
   Show/Hide
C18H17N9OS
  1
1
IC50 = 5820 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS