Brief Information of the Compound and Protein
Compound Name
(7R)-7-ethyl-5-methyl-8-(1H-pyrazol-4-yl)-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one
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PubChem ID
CID: 58405948
SID: 163684094
Canonical SMILES
CC[C@H]1N(c2cn[nH]c2)c2nc(ncc2N(C)C1=O)-c1c[nH]nc1-c1nccs1
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Compound Formula C18H17N9OS
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
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Other protein kinase PLK family
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Other protein kinase PLK2
Uniprot ID
Q9NYY3
Gene Name
PLK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 5820 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 92 nM