| Compound ID |
Compound Name |
Compound Formula |
|
CP0401448
|
4-(2-(3-fluorophenoxy)phenyl)piperidine
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|
C17H18FNO
|
2
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0155177
|
[4-[[1-(2,2-difluoroethyl)-1,2,4-triazol-3-yl]methyl]piperazin-1-yl]-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]methanone
Show/Hide
|
C28H34F2N6O2
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0401481
|
4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine
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|
C17H17F2NO
|
2
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0430772
|
4-(2-(3-chlorophenoxy)phenyl)piperidine
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|
C17H18ClNO
|
2
|
| 1 |
EC50 = 49 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0113725
|
[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-[4-[[1-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]methyl]piperazin-1-yl]methanone
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|
C28H33F3N6O2
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0373835
|
1-(2-(benzyloxy)phenyl)piperazine
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|
C17H20N2O
|
2
|
| 1 |
EC50 = 83 nM
|
|
|
| 2 |
Ki = 168 nM
|
|
|
|
CP0155176
|
[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-[4-[[6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]methyl]piperazin-1-yl]methanone
Show/Hide
|
C32H36N6O3
|
1
|
| 1 |
EC50 = 251 nM
|
|
|
|
CP0155174
|
[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-[4-[[6-(5-methyl-1,3,4-oxadiazol-2-yl)pyridin-2-yl]methyl]piperazin-1-yl]methanone
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|
C32H36N6O3
|
1
|
| 1 |
EC50 = 254 nM
|
|
|
|
CP0393494
|
methyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
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|
C20H18ClN5O4S
|
3
|
| 1 |
EC50 = 310 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 = 3380 nM
|
|
|
|
CP0126436
|
[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-[4-(pyridin-2-ylmethyl)piperazin-1-yl]methanone
Show/Hide
|
C29H34N4O2
|
1
|
| 1 |
EC50 = 339 nM
|
|
|
|
CP0438753
|
4-(3-fluoro-2-phenoxyphenyl)piperidine
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|
C17H18FNO
|
2
|
| 1 |
EC50 = 358 nM
|
|
|
| 2 |
Ki = 1370 nM
|
|
|
|
CP0126419
|
methyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-bromothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
Show/Hide
|
C20H18BrN5O4S
|
3
|
| 1 |
EC50 = 400 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 = 3560 nM
|
|
|
|
CP0405283
|
ethyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
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|
C21H20ClN5O4S
|
2
|
| 1 |
EC50 = 490 nM
|
|
|
| 2 |
IC50 = 3980 nM
|
|
|
|
CP0126440
|
[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-[4-[[2-(2,2,2-trifluoroethyl)tetrazol-5-yl]methyl]piperazin-1-yl]methanone
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|
C27H32F3N7O2
|
1
|
| 1 |
EC50 = 627 nM
|
|
|
|
CP0393811
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-bromothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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|
C20H19BrN6O3S
|
3
|
| 1 |
EC50 = 670 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 = 6110 nM
|
|
|
|
CP0393806
|
(1S,2R,3S,4R,5S)-4-[6-[2-(5-chlorothiophen-2-yl)ethynyl]-4-(methylamino)imidazo[4,5-c]pyridin-1-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C21H20ClN5O3S
|
3
|
| 1 |
EC50 = 740 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 = 5060 nM
|
|
|
|
CP0092246
|
[4-[[2-(2,2-difluoroethyl)tetrazol-5-yl]methyl]piperazin-1-yl]-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]methanone
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|
C27H33F2N7O2
|
1
|
| 1 |
EC50 = 827 nM
|
|
|
|
CP0236158
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(propylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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|
C22H23ClN6O3S
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0393511
|
propyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
Show/Hide
|
C22H22ClN5O4S
|
3
|
| 1 |
EC50 = 980 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 = 7900 nM
|
|
|
|
CP0089367
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C20H19ClN6O3S
|
3
|
| 1 |
EC50 = 1180 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0092244
|
[4-[[2-(cyclopropylmethyl)tetrazol-5-yl]methyl]piperazin-1-yl]-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]methanone
Show/Hide
|
C29H37N7O2
|
1
|
| 1 |
EC50 = 1390 nM
|
|
|
|
CP0196123
|
[4-[(2-ethyltetrazol-5-yl)methyl]piperazin-1-yl]-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]methanone
Show/Hide
|
C27H35N7O2
|
1
|
| 1 |
EC50 = 1520 nM
|
|
|
|
CP0076893
|
methyl (2S,3S,4R,5R)-5-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-3,4-dihydroxyoxolane-2-carboxylate
Show/Hide
|
C18H16ClN5O5S
|
3
|
| 1 |
EC50 = 1520 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 = 2690 nM
|
|
|
|
CP0358468
|
(1S,2R,3S,4R,5S)-4-[2-[2-(3,4-difluorophenyl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C22H20F2N6O3
|
3
|
| 1 |
EC50 = 1760 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0060502
|
1-(6-(methylthio)naphthalen-2-yl)propan-2-amine
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|
C10H15NS
|
1
|
| 1 |
EC50 = 34673.69 nM
|
|
|
|
CP0422470
|
(3S)-3-[(R)-(2-chloro-3,6-difluorophenoxy)-phenylmethyl]pyrrolidine
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|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 0.3162 nM
|
|
|
|
CP0410931
|
(3S)-3-[(R)-(2,6-dichlorophenoxy)-phenylmethyl]pyrrolidine
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|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 0.3981 nM
|
|
|
|
CP0410934
|
(3S)-3-[(R)-(2-methoxyphenoxy)-phenylmethyl]pyrrolidine
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|
C18H21NO2
|
1
|
| 1 |
IC50 = 0.3981 nM
|
|
|
|
CP0002121
|
methyl (1R,2S,3R,5S)-3-(3-fluoro-4-methylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
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|
C16H20FNO2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0186086
|
(3S)-3-[(R)-phenyl-(2,3,6-trichlorophenoxy)methyl]pyrrolidine
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|
C17H16Cl3NO
|
1
|
| 1 |
IC50 = 0.5012 nM
|
|
|
|
CP0335572
|
(3R)-3-[(S)-(2-chloro-3,6-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 0.5012 nM
|
|
|
|
CP0368081
|
(3S)-3-[(R)-(4-chloro-2-methoxyphenoxy)-phenylmethyl]pyrrolidine
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|
C18H20ClNO2
|
1
|
| 1 |
IC50 = 0.5012 nM
|
|
|
|
CP0418832
|
(3R)-3-[(S)-(2-nitrophenoxy)-phenylmethyl]pyrrolidine
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|
C17H18N2O3
|
1
|
| 1 |
IC50 = 0.5012 nM
|
|
|
|
CP0418836
|
(3R)-3-[(S)-(3-chlorophenoxy)-phenylmethyl]pyrrolidine
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|
C17H18ClNO
|
1
|
| 1 |
IC50 = 0.5012 nM
|
|
|
|
CP0575279
|
(S)-9-methyl-6-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)-2- (methylthio)-6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
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|
C23H27N5O2S2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0874562
|
9-Benzo[1,3]dioxol-5-yl-1,2,3,9-tetrahydro-4,9a-diaza-fluoren-9-ol hydrochloride
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|
C18H17ClN2O3
|
2
|
| 1 |
IC50 = 0.62 nM
|
|
|
| 2 |
Ki = 8.8 nM
|
|
|
|
CP0386071
|
(3S)-3-[(R)-phenyl-(2,3,6-trifluorophenoxy)methyl]pyrrolidine
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|
C17H16F3NO
|
1
|
| 1 |
IC50 = 0.631 nM
|
|
|
|
CP0037646
|
Midalcipran
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|
C15H22N2O
|
5
|
| 1 |
IC50 = 0.7943 nM
|
|
|
| 2 |
IC50 = 41 nM
|
|
|
| 3 |
IC50 = 77 nM
|
|
|
| 4 |
IC50 = 5500 nM
|
|
|
| 5 |
Ki = 85 nM
|
|
|
|
CP0386070
|
(3S)-3-[(R)-(2,6-dichloro-3,5-difluorophenoxy)-phenylmethyl]pyrrolidine
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|
C17H15Cl2F2NO
|
1
|
| 1 |
IC50 = 0.7943 nM
|
|
|
|
CP0418834
|
(3S)-3-[(R)-(2,6-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17F2NO
|
1
|
| 1 |
IC50 = 0.7943 nM
|
|
|
|
CP0447961
|
(3R)-3-[(S)-(2-methylphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 0.7943 nM
|
|
|
|
CP0481075
|
(3R)-3-[(S)-(2,3-dichlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 0.7943 nM
|
|
|
|
CP0483919
|
(3S)-3-[(R)-phenyl-(2,3,5,6-tetrafluorophenoxy)methyl]pyrrolidine
Show/Hide
|
C17H15F4NO
|
1
|
| 1 |
IC50 = 0.7943 nM
|
|
|
|
CP0004274
|
methyl (1R,2S,3S,5S)-3-(4-chloro-3-methylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
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|
C16H20ClNO2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0062351
|
42-548
Show/Hide
|
C16H13ClN2O
|
5
|
| 1 |
IC50 = 0.92 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
| 3 |
Ki = 11.3 nM
|
|
|
| 4 |
Ki = 13.5 nM
|
|
|
| 5 |
Ki = 18 nM
|
|
|
|
CP0410904
|
(3S)-3-[(R)-(2,4-dichloro-6-fluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H16Cl2FNO
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0447518
|
(3R)-3-[(S)-(2,6-dichloro-3,5-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H15Cl2F2NO
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0002119
|
methyl (1R,2S,3S,5S)-3-(4-chloro-3-methylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C17H22ClNO2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0335573
|
(3R)-3-[(S)-phenyl-(2,3,6-trichlorophenoxy)methyl]pyrrolidine
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|
C17H16Cl3NO
|
1
|
| 1 |
IC50 = 1.259 nM
|
|
|
|
CP0454562
|
5-(4-Chloro-phenyl)-7-methoxy-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
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|
C17H15ClN2O2
|
2
|
| 1 |
IC50 = 1.46 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0152488
|
(1S,2R)-1-(2-ethylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
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|
C19H23NO2
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0008168
|
CAS_136434-34-9
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|
C18H19NOS
|
8
|
| 1 |
IC50 = 1.585 nM
|
|
|
| 2 |
IC50 = 5 nM
|
|
|
| 3 |
IC50 = 8.9 nM
|
|
|
| 4 |
IC50 = 19 nM
|
|
|
| 5 |
IC50 = 29 nM
|
|
|
| 6 |
IC50 = 515 nM
|
|
|
| 7 |
Ki = 6.7 nM
|
|
|
| 8 |
Ki = 45 nM
|
|
|
|
CP0171771
|
(3S)-3-[(R)-(2,3-dichlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 1.585 nM
|
|
|
|
CP0262849
|
(3R)-3-[(S)-phenyl-(2,3,5,6-tetrafluorophenoxy)methyl]pyrrolidine
Show/Hide
|
C17H15F4NO
|
1
|
| 1 |
IC50 = 1.585 nM
|
|
|
|
CP0248131
|
N-(azetidin-3-ylmethyl)-N-[(2-chlorophenyl)methyl]aniline;2,2,2-trifluoroacetic acid
Show/Hide
|
C19H20ClF3N2O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0460597
|
5-(4-Chloro-phenyl)-6-methoxy-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
Show/Hide
|
C17H15ClN2O2
|
2
|
| 1 |
IC50 = 1.73 nM
|
|
|
| 2 |
Ki = 23.1 nM
|
|
|
|
CP0573052
|
Reboxe- tine
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|
C19H23NO3
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0401039
|
9-(4-Hydroxy-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-fluoren-9-ol
Show/Hide
|
C17H16N2O2
|
2
|
| 1 |
IC50 = 1.9 nM
|
|
|
| 2 |
Ki = 380 nM
|
|
|
|
CP0083658
|
(S,S)-reboxetine
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|
C19H23NO3
|
3
|
| 1 |
IC50 = 1.995 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
Ki = 1.04 nM
|
|
|
|
CP0262850
|
(3S)-3-[(R)-(2-chloro-4-fluorophenoxy)-phenylmethyl]pyrrolidine
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|
C17H17ClFNO
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0262851
|
(3S)-3-[(R)-(3-chlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H18ClNO
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0422449
|
(3R)-3-[(S)-(2,6-dichlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0452446
|
(3R)-3-[(S)-(2-methoxyphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0465334
|
(3S)-3-[(R)-(2,4-dichlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0427486
|
3-[(2-phenylphenoxy)-piperidin-4-ylmethyl]pyridine
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|
C23H24N2O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0297509
|
(1S,2R)-2-((methylamino)methyl)-1-(2-(methylthio)phenoxy)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0316340
|
(1S,2R)-1-(2,4-dimethylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0401308
|
(1R,3S)-5-Methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decane
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|
C17H21N
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0340079
|
(1R,2R)-2-(aminomethyl)-N,N-bis(prop-2-enyl)-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H20N2OS
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0410932
|
2-[3,5-dichloro-2-[(R)-phenyl-[(3S)-pyrrolidin-3-yl]methoxy]phenyl]pyridine
Show/Hide
|
C22H20Cl2N2O
|
1
|
| 1 |
IC50 = 2.512 nM
|
|
|
|
CP0486499
|
(1S,2R)-2-(aminomethyl)-N,N-bis(prop-2-enyl)-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H20N2OS
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0463383
|
5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
Show/Hide
|
C16H14N2O
|
2
|
| 1 |
IC50 = 2.8 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0490533
|
(1S,2R)-2-(aminomethyl)-N-prop-2-enyl-N-prop-2-ynyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H18N2OS
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0433653
|
(1S,2R)-2-(aminomethyl)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-ethenyl-N-ethylcyclopropane-1-carboxamide
Show/Hide
|
C17H22N2O3
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0364766
|
(S)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C17H19Cl2N3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0299583
|
(1S,2R)-1-(2,3-dimethylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0317509
|
(1S,2R)-1-(3-fluoro-2-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0330446
|
(1S,2R)-2-((methylamino)methyl)-1-(2-(naphthalen-1-yl)phenoxy)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C27H25NO2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0332009
|
(1S,2R)-2-((methylamino)methyl)-1-(o-tolyloxy)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0262531
|
((3S,4S)-4-(3-fluoro-2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H20FNO2
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0262532
|
N-methyl-1-[(3S,4S)-4-[2-(trifluoromethyl)phenoxy]-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
|
C18H18F3NO2
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 6 nM
|
|
|
|
CP0564284
|
8-methoxy-1-methyl-4-[3-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydropyrido[2,3-e][1,4]diazepin-5-one
Show/Hide
|
C24H28N4O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0711358
|
3-(Naphthalen-2-yl(phenoxy)methyl)azetidine hydrochloride
Show/Hide
|
C20H20ClNO
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0165144
|
(3R)-3-[(S)-(3,5-dichlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 3.162 nM
|
|
|
|
CP0462402
|
(3R)-3-[(R)-(2-methoxyphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 3.162 nM
|
|
|
|
CP0105628
|
US9085531, 40
Show/Hide
|
C18H17NS
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0510889
|
(1S,2R)-2-(aminomethyl)-N-(2-fluoroprop-2-enyl)-N-(2-methoxyethyl)-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H21FN2O2S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0410903
|
(3R)-3-[(R)-(2-chloro-3,6-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0410930
|
(3S)-3-[(R)-(4-chloro-2-methylphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H20ClNO
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0418833
|
(3R)-3-[(S)-(2-fluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H18FNO
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0431952
|
(3R)-3-[(S)-(3,5-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17F2NO
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0447524
|
(3S)-3-[(S)-(2-chloro-3,6-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0454175
|
(3S)-3-[(R)-(2-chlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H18ClNO
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0112278
|
(S)-N-(2-chloro-3-methylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C17H25ClN2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0035248
|
(1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0293739
|
(1S,2R)-1-(3-hydroxy-2-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0262530
|
((3S,4S)-4-(2-fluoro-6-(trifluoromethyl)phenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H17F4NO2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0311652
|
((3S,4S)-4-(2-fluoro-6-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H20FNO2
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
|
CP0413109
|
9-(4-Methoxy-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-fluoren-9-ol
Show/Hide
|
C18H18N2O2
|
2
|
| 1 |
IC50 = 4.1 nM
|
|
|
| 2 |
Ki = 84 nM
|
|
|
|
CP0055808
|
3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H22N2
|
2
|
| 1 |
IC50 = 4.2 nM
|
|
|
| 2 |
Ki = 2.5 nM
|
|
|
|
CP0139009
|
(1R,2R)-2-(aminomethyl)-N-ethyl-N-(2-fluoroprop-2-enyl)-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C14H19FN2OS
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0438758
|
5-(4-Chloro-phenyl)-9-methoxy-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
Show/Hide
|
C17H15ClN2O2
|
2
|
| 1 |
IC50 = 4.7 nM
|
|
|
| 2 |
Ki = 6.8 nM
|
|
|
|
CP0392690
|
6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol
Show/Hide
|
C17H15ClN2O
|
3
|
| 1 |
IC50 = 4.9 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
| 3 |
Ki = 18.2 nM
|
|
|
|
CP0438751
|
5-(4-Chloro-phenyl)-9-fluoro-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
Show/Hide
|
C16H12ClFN2O
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0187117
|
(S)-N-(3-chloro-2-methylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C17H25ClN2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0293566
|
(S)-N-(2,3-dichlorobenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C16H22Cl2N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0309340
|
(R)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C17H19Cl2N3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0051283
|
ATOMOXETINE
Show/Hide
|
C17H21NO
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 5.1 nM
|
|
|
|
CP0138141
|
(1S,2R)-1-(2-fluoro-6-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0266875
|
(1S,2R)-1-(4-fluoro-2-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0336664
|
(1S,2R)-1-(2-chlorophenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C17H18ClNO2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0137424
|
N-methyl-1-[(3S,4S)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
|
C18H21NO2
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 18 nM
|
|
|
|
CP0137036
|
(3S)-3-[(R)-(2-methoxy-4-nitrophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H20N2O4
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0137037
|
(3S)-3-[(R)-(3,5-dichlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0447163
|
(3S)-3-[(S)-(2-methoxyphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0447527
|
(3R)-3-[(S)-(4-chlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H18ClNO
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0484136
|
2-[5-chloro-3-methyl-2-[(R)-phenyl-[(3S)-pyrrolidin-3-yl]methoxy]phenyl]pyridine
Show/Hide
|
C23H23ClN2O
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0415130
|
(1S,2R)-N-allyl-2-(aminomethyl)-N-ethyl-1-(thiophen-3-yl)cyclopropanecarboxamide
Show/Hide
|
C14H20N2OS
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0497917
|
(1R,2R)-2-(aminomethyl)-N,N-bis(prop-2-ynyl)-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H16N2OS
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0005907
|
5-[(1R,2S,3S,5S)-3-(4-chloro-3-methylphenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-3-methyl-1,2-oxazole
Show/Hide
|
C19H23ClN2O
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0004052
|
methyl (1R,2S,3R,5S)-3-(4-chloro-3-methylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C17H22ClNO2
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
Show/Hide
|
C8H11NO2
|
2
|
| 1 |
IC50 = 6.63 nM
|
|
|
| 2 |
Ki > 28000 nM
|
|
|
|
CP0553877
|
6-(2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)-1,3-benzothiazole
Show/Hide
|
C17H16N2S
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0461234
|
5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindole
Show/Hide
|
C16H13ClN2
|
2
|
| 1 |
IC50 = 6.9 nM
|
|
|
| 2 |
Ki = 170 nM
|
|
|
|
CP0085238
|
6-methoxy-2-methyl-3-[(1S)-3-methyl-1-[(3S)-pyrrolidin-3-yl]butoxy]pyridine
Show/Hide
|
C16H26N2O2
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0177511
|
(2-methyl-benzyl)-(S)-pyrrolidin-3-yl-(tetrahydro-pyran-4-yl)-amine
Show/Hide
|
C17H26N2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0320330
|
(S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C18H28N2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0318578
|
(1S,2R)-1-(5-fluoro-2-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0319581
|
N-methyl-1-[(1R,2S)-1-(2-methylphenoxy)-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
|
C18H21NO
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0204994
|
N-methyl-1-[(1R,2S)-1-(2-methylphenoxy)-1,2,3,4-tetrahydronaphthalen-2-yl]methanamine
Show/Hide
|
C19H23NO
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0311754
|
((3R,4R)-4-(2-ethylphenoxy)-3,4-dihydro-2H-chromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0189276
|
(S)-2-amino-9-methyl- 6-(3-(3-(methylamino)- 1-(thiophen-2- yl)propoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C22H26N6O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0560473
|
2-(ethylamino)-9- methyl-6-(4-((3- (methylamino)-1- phenylpropoxy)methyl) phenyl)-6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0436613
|
1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H21NO3
|
2
|
| 1 |
IC50 = 7.6 nM
|
|
|
| 2 |
Ki = 219 nM
|
|
|
|
CP0474034
|
4-(1-benzothiophen-7-yl)-2-methyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C18H17NS
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0101880
|
3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine
Show/Hide
|
C17H21NO2
|
4
|
| 1 |
IC50 = 7.943 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
| 3 |
IC50 = 18 nM
|
|
|
| 4 |
IC50 = 20 nM
|
|
|
|
CP0418831
|
(3S)-3-[(R)-(2,4-difluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17F2NO
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0422453
|
(3S)-3-[(R)-(2-methylphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0216263
|
(R)-N-(2,3-dimethylbenzyl)-N-(pyridin-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C19H25N3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0457464
|
4-[(2,3-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0422641
|
((3S,4S)-4-(2-ethyl-6-fluorophenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H22FNO2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0193010
|
3-methyl-4-((3S,4S)-3-((methylamino)methyl)-3,4-dihydro-1H-isochromen-4-yloxy)phenol
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0193012
|
((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18ClNO2
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 17 nM
|
|
|
|
CP0333810
|
(2S,4R)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0065146
|
(R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Show/Hide
|
C16H20ClNO2
|
2
|
| 1 |
IC50 = 8.2 nM
|
|
|
| 2 |
Ki = 37 nM
|
|
|
|
CP0486500
|
(1S,2R)-2-(aminomethyl)-N,N-bis(prop-2-ynyl)-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H16N2OS
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0490604
|
[(1S,2R)-2-(aminomethyl)-1-thiophen-3-ylcyclopropyl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C18H20N2OS
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0105626
|
4-[(4R)-4-(1-benzothiophen-5-yl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]morpholine
Show/Hide
|
C22H24N2OS
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0511527
|
(1S,2R)-2-(aminomethyl)-N-cyclopropyl-N-prop-2-enyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H20N2OS
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0551225
|
1-(2-(2-ethoxyphenyl)-1-phenylethyl)-1,4-diazepane
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0857555
|
(+)-4-(1H-indol-6-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C18H18N2
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0187116
|
(S)-N-(2,3-dichlorobenzyl)-N-(cyclopropylmethyl)pyrrolidin-3-amine
Show/Hide
|
C15H20Cl2N2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0296901
|
(S)-pyrrolidin-3-yl-(tetrahydro-pyran-4-yl)-(2-trifluoromethyl-benzyl)-amine
Show/Hide
|
C17H23F3N2O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0465776
|
((3S,4S)-4-(3-chloro-2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H20ClNO2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0001465
|
(2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-morpholin-2-ol
Show/Hide
|
C15H22ClNO2
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 31 nM
|
|
|
|
CP0553321
|
(S)-9-methyl-6-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C22H25N5O2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0099049
|
1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO
|
2
|
| 1 |
IC50 = 9.4 nM
|
|
|
| 2 |
Ki = 216 nM
|
|
|
|
CP0380196
|
7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
Show/Hide
|
C16H11Cl3N2O
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
Ki = 40 nM
|
|
|
|
CP0096209
|
2-(methylaminomethyl)-1-(2-methylphenyl)sulfanyl-1,3-dihydroinden-2-ol
Show/Hide
|
C18H21NOS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0885339
|
3-((3,4-Dichlorophenyl)(propoxy)methyl)azetidine hydrochloride
Show/Hide
|
C13H18Cl3NO
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0305182
|
(3R)-3-[(S)-phenyl-(2,3,5-trichlorophenoxy)methyl]pyrrolidine
Show/Hide
|
C17H16Cl3NO
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0418837
|
(3R)-3-[(S)-(2-chlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H18ClNO
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0422471
|
(3S)-3-[(R)-(4-chloro-2-fluorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
|
C17H17ClFNO
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0447521
|
(3S)-3-[(S)-phenyl-[4-(trifluoromethyl)phenoxy]methyl]pyrrolidine
Show/Hide
|
C18H18F3NO
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0571510
|
(S)-2,9-dimethyl-6-(3- (3-(methylamino)-1- (thiophen-2- yl)propoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C23H27N5O2S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0386325
|
3-[2-(4-chloro-3-fluorophenyl)-2-phenoxyethyl]azetidine
Show/Hide
|
C17H17ClFNO
|
1
|
| 1 |
IC50 = 10.6 nM
|
|
|
|
CP0381886
|
(1R,3S,5R)-5-Phenyl-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-ol
Show/Hide
|
C22H25NO
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0334501
|
(S)-N-(3-methoxy-2-methylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C18H28N2O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0456844
|
(5R,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C17H18Cl2N2O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0339523
|
1-[2-(4-chloro-2-methylphenoxy)-5-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-N-methylmethanamine
Show/Hide
|
C18H21ClN2O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0360029
|
1-[2-(2,4-dichlorophenoxy)phenyl]-N,N-dimethylmethanamine
Show/Hide
|
C15H15Cl2NO
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0196465
|
(R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C19H23NO3
|
3
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
| 3 |
Ki = 5 nM
|
|
|
|
CP0364578
|
(1S,2R)-1-(2-fluorophenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C17H18FNO2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0388487
|
((3S,4S)-4-(5-fluoro-2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0006239
|
3-ethyl-5-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,2-oxazole
Show/Hide
|
C20H26N2O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0857556
|
(+)-4-(1H-indazol-5-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C17H17N3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0099044
|
(1S)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO
|
2
|
| 1 |
IC50 = 11.3 nM
|
|
|
| 2 |
Ki = 109 nM
|
|
|
|
CP0154537
|
1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C19H23NO
|
2
|
| 1 |
IC50 = 11.7 nM
|
|
|
| 2 |
Ki = 136 nM
|
|
|
|
CP0035841
|
(3S)-N-(oxan-4-yl)-N-[(2-phenylphenyl)methyl]pyrrolidin-3-amine
Show/Hide
|
C22H28N2O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0157735
|
(S)-N-(2,3-dimethylbenzyl)-N-(pyridin-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C19H25N3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0452744
|
[(1S,2R)-2-(aminomethyl)-1-thiophen-3-ylcyclopropyl]-(1,4-benzoxazin-4-yl)methanone
Show/Hide
|
C17H16N2O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0877734
|
3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride
Show/Hide
|
C17H22ClNO
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0424725
|
1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO2
|
2
|
| 1 |
IC50 = 12.4 nM
|
|
|
| 2 |
Ki = 150 nM
|
|
|
|
CP0157738
|
(S)-N-(3-fluoro-2-(trifluoromethyl)benzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C17H22F4N2O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0387620
|
3-[(2-ethoxyphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C19H24N2O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0383845
|
(1R,2R)-2-(aminomethyl)-N-prop-2-enyl-N-(1,3-thiazol-2-ylmethyl)-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C16H19N3OS2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0526906
|
((3S,4S)-4-(4-fluoro-2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0008968
|
(S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propylmorpholine
Show/Hide
|
C16H24ClNO2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0863203
|
(+)-4-(1H-indazol-6-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C17H17N3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0137447
|
(3R)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine
Show/Hide
|
C18H19NOS
|
2
|
| 1 |
IC50 = 13.2 nM
|
|
|
| 2 |
Ki = 61.3 nM
|
|
|
|
CP0364814
|
1-[2-(4-chloro-2-methoxyphenoxy)phenyl]-N,N-dimethylmethanamine
Show/Hide
|
C16H18ClNO2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0461243
|
3-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0082300
|
(S)-N-(biphenyl-2-ylmethyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C21H26N2O
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0440601
|
N-methyl-1-[(3S,4S)-4-(2-methylsulfanylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
|
C18H21NO2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0004051
|
5-[(1R,2S,3S,5S)-3-(4-chloro-3-methylphenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-3-phenyl-1,2-oxazole
Show/Hide
|
C24H25ClN2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0054654
|
3-[2-(4-chloro-3-fluorophenyl)-2-(3-fluorophenoxy)ethyl]azetidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0142617
|
3-[2-(4-chloro-3-fluorophenyl)-2-(3-methylphenoxy)ethyl]azetidine
Show/Hide
|
C18H19ClFNO
|
1
|
| 1 |
IC50 = 14.7 nM
|
|
|
|
CP0287699
|
(R)-N-(2,3-dichlorobenzyl)-N-(cyclopropylmethyl)pyrrolidin-3-amine
Show/Hide
|
C15H20Cl2N2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0153254
|
1-[2-(2-chlorophenoxy)phenyl]-N,N-dimethylmethanamine
Show/Hide
|
C15H16ClNO
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0393803
|
1-(2-(2-ethoxyphenyl)-1-(pyridin-3-yl)ethyl)piperazine
Show/Hide
|
C19H25N3O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0439688
|
(1R,2R)-2-(aminomethyl)-N-ethyl-N-prop-2-enyl-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C14H20N2OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0465770
|
((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0054655
|
3-[2-(4-chloro-3-fluorophenyl)-2-(2-fluorophenoxy)ethyl]azetidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 15.9 nM
|
|
|
|
CP0301340
|
(R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine hydrochloride
Show/Hide
|
C20H26N2O
|
3
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 18 nM
|
|
|
| 3 |
Ki = 12 nM
|
|
|
|
CP0436266
|
1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine
Show/Hide
|
C20H26N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0659604
|
(R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine hydrochloride
Show/Hide
|
C20H27ClN2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0298509
|
4-[(2,3-dichlorophenoxy)-phenylmethyl]piperidine
Show/Hide
|
C18H19Cl2NO
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0137912
|
(S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C15H19Cl3N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0808299
|
3-((3,4-Dichlorophenoxy)(naphthalen-2-yl)methyl)azetidine hydrochloride
Show/Hide
|
C20H18Cl3NO
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0459699
|
BDBM50054521
Show/Hide
|
C22H24N2OS
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0285512
|
4-(4-chloro-2-methylphenoxy)-N,N-dimethyl-3-(methylaminomethyl)benzamide
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0320328
|
1-[2-(2,4-dichlorophenoxy)-5-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-N-methylmethanamine
Show/Hide
|
C17H18Cl2N2O3S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0096207
|
(1S,2R)-1-(2-methoxyphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0434908
|
(1R,2R)-2-(aminomethyl)-N-cyclopropyl-N-prop-2-enyl-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H20N2OS
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0250545
|
N-(azetidin-3-ylmethyl)-N-[(2,3-dichlorophenyl)methyl]aniline;2,2,2-trifluoroacetic acid
Show/Hide
|
C19H19Cl2F3N2O2
|
1
|
| 1 |
IC50 = 17.6 nM
|
|
|
|
CP0453321
|
(1R,3S,5S)-5-Propyl-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-ol
Show/Hide
|
C19H27NO
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0394704
|
4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)pentan-1-one
Show/Hide
|
C17H25NO
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
Ki = 259 nM
|
|
|
|
CP0530540
|
1-[4-(4-chloro-2-ethylphenoxy)pyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
|
C16H19ClN2O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0442457
|
1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-butan-1-one
Show/Hide
|
C14H17Cl2NO
|
2
|
| 1 |
IC50 = 18.5 nM
|
|
|
| 2 |
Ki = 262 nM
|
|
|
|
CP0662047
|
(S)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine hydrochloride
Show/Hide
|
C20H27ClN2O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0383846
|
(1R,2R)-2-(aminomethyl)-N-ethyl-N-prop-2-ynyl-1-thiophen-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C14H18N2OS
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0004407
|
(2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmorpholin-2-ol
Show/Hide
|
C14H20ClNO2
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 43.4 nM
|
|
|
|
CP0004090
|
2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5,6-dimethyl-1H-benzimidazole
Show/Hide
|
C23H26ClN3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0396822
|
BDBM50054516
Show/Hide
|
C17H16N2S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0436863
|
1-(4-propynylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C18H23NO
|
2
|
| 1 |
IC50 = 19.3 nM
|
|
|
| 2 |
Ki = 69.8 nM
|
|
|
|
CP0290236
|
1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO
|
2
|
| 1 |
IC50 = 19.7 nM
|
|
|
| 2 |
Ki = 425 nM
|
|
|
|
CP0215426
|
(S)-N-(2-methyl-3-(trifluoromethyl)benzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C18H25F3N2O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0486501
|
(1S,2R)-2-(aminomethyl)-N-(2-methoxyethyl)-N-prop-2-enyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H22N2O2S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0535158
|
[(1S,2R)-2-(aminomethyl)-1-thiophen-3-ylcyclopropyl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
Show/Hide
|
C18H20N2OS
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0394672
|
1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H19Cl2NO
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
Ki = 37.8 nM
|
|
|
|
CP0360028
|
1-[2-(4-chloro-2-fluorophenoxy)phenyl]-N,N-dimethylmethanamine
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C15H15ClFNO
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1
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| 1 |
IC50 = 21 nM
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CP0407225
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1-(2-(2-ethoxyphenyl)-1-(thiazol-5-yl)ethyl)piperazine
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C17H23N3OS
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1
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| 1 |
IC50 = 21 nM
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CP0439277
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2-[(1R,2R)-2-(Aminomethyl)-1-(2-thienyl)cyclopropanecarbonyl] isoindoline
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C17H18N2OS
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1
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| 1 |
IC50 = 21 nM
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CP0885484
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3-((4-Chloro-3-fluorophenyl)(phenoxy)methyl)azetidine hydrochloride
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C16H16Cl2FNO
|
1
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| 1 |
IC50 = 21 nM
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CP0153252
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1-[2-(4-chloro-2-methylphenoxy)phenyl]-N-methylmethanamine
Show/Hide
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C15H16ClNO
|
1
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| 1 |
IC50 = 22 nM
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CP0058981
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1-(2-(2-chlorophenyl)-1-phenylethyl)piperazine
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C18H21ClN2
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1
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| 1 |
IC50 = 22 nM
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CP0393804
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1-(2-(2-ethoxyphenyl)-1-(3-fluorophenyl)ethyl)piperazine
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C20H25FN2O
|
1
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| 1 |
IC50 = 22 nM
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CP0394252
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1-[4-(4-chloro-2-ethylphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
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C16H19ClN2O
|
2
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| 1 |
IC50 = 22 nM
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| 2 |
Ki = 74 nM
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CP0047005
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(+)-1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazine
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C19H24N2O
|
1
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| 1 |
IC50 = 22 nM
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CP0474033
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2-methyl-4-pyrazolo[1,5-a]pyridin-6-yl-3,4-dihydro-1H-isoquinoline
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C17H17N3
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1
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| 1 |
IC50 = 22 nM
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CP0424737
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4-(2-pyrrolidin-1-yl-pentanoyl)benzoic acid methyl Ester
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C17H23NO3
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2
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| 1 |
IC50 = 22.8 nM
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| 2 |
Ki = 1140 nM
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CP0375744
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(1R,3S,5R)-5-(4-Chloro-phenyl)-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-ol
Show/Hide
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C22H24ClNO
|
1
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| 1 |
IC50 = 23 nM
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CP0396973
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3-[(3-chlorophenoxy)-piperidin-4-ylmethyl]pyridine
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C17H19ClN2O
|
1
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| 1 |
IC50 = 23 nM
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CP0447870
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3-[(2-phenoxyphenoxy)-piperidin-4-ylmethyl]pyridine
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C23H24N2O2
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1
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| 1 |
IC50 = 23 nM
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CP0492250
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2-[(2,3-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
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C17H18Cl2N2O
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1
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| 1 |
IC50 = 23 nM
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CP0372829
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2-Aminomethyl-5-(phenyl)tetrahydrofuran
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C11H15NO
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2
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| 1 |
IC50 = 23 nM
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| 2 |
Ki = 2767 nM
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CP0163723
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(S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
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C15H20Cl2N2O
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2
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| 1 |
IC50 = 23 nM
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| 2 |
Ki = 52 nM
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CP0387621
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3-[(2,3-difluorophenoxy)-piperidin-4-ylmethyl]pyridine
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C17H18F2N2O
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1
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| 1 |
IC50 = 24 nM
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CP0419056
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(S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide
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C19H24N2O
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1
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| 1 |
IC50 = 24 nM
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CP0006168
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(S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylmorpholine
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C15H22ClNO2
|
1
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| 1 |
IC50 = 24 nM
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CP0379291
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N-(azetidin-3-ylmethyl)-N-[(3-methylphenyl)methyl]aniline;2,2,2-trifluoroacetic acid
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C20H23F3N2O2
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1
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| 1 |
IC50 = 24.2 nM
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CP0441742
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1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pent-4-ene-1-one
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C15H17Cl2NO
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2
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| 1 |
IC50 = 24.9 nM
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| 2 |
Ki = 509 nM
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CP0285511
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N-[4-(4-chloro-2-methylphenoxy)-3-(methylaminomethyl)phenyl]methanesulfonamide
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C16H19ClN2O3S
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1
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| 1 |
IC50 = 25 nM
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CP0452988
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1-(2-(2-chlorophenyl)-1-(3-fluorophenyl)ethyl)piperazine
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C18H20ClFN2
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1
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| 1 |
IC50 = 25 nM
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CP0509921
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1-[4-(2,4-dichlorophenoxy)pyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
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C14H14Cl2N2O
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1
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| 1 |
IC50 = 25 nM
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CP0387766
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(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)cyclopropanecarboxamide
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C15H18Cl2N2O
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1
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| 1 |
IC50 = 25 nM
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CP0364813
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4-(4-chloro-2-methylphenoxy)-N-methyl-3-(methylaminomethyl)benzamide
Show/Hide
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C17H19ClN2O2
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1
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| 1 |
IC50 = 26 nM
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CP0161358
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1-[4-(4-chloro-2-methoxyphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
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C16H19ClN2O2
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1
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| 1 |
IC50 = 26 nM
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CP0302281
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1-[4-(4-chloro-2-methylphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
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C16H19ClN2O
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1
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| 1 |
IC50 = 26 nM
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CP0433621
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1-[4-(2-bromo-4-chlorophenoxy)pyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
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C14H14BrClN2O
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1
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| 1 |
IC50 = 26 nM
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CP0453237
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N-methyl-1-[(3R,4R)-4-(2-methylphenoxy)-3,4-dihydro-2H-chromen-3-yl]methanamine
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C18H21NO2
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2
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| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 40 nM
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CP0256331
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((3R,4R)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chromen-3-yl)-N-methylmethanamine
Show/Hide
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C17H18ClNO2
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2
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| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 36 nM
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CP0004314
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5-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-3-(4-methoxyphenyl)-1,2-oxazole
Show/Hide
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C24H25ClN2O2
|
1
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| 1 |
IC50 = 26 nM
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CP0256364
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((3R,4R)-4-(2,3-dimethylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
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C19H23NO2
|
1
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| 1 |
IC50 = 27 nM
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CP0374861
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1-(2-(2-ethoxyphenyl)-1-(4-fluorophenyl)ethyl)piperazine
Show/Hide
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C20H25FN2O
|
1
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| 1 |
IC50 = 28 nM
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CP0040444
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(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
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C15H20Cl2N2O
|
1
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| 1 |
IC50 = 28 nM
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CP0403189
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1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
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C16H23NO
|
2
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| 1 |
IC50 = 28.3 nM
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| 2 |
Ki = 195 nM
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CP0382159
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(1R,2R)-2-(aminomethyl)-1-(5-bromothiophen-2-yl)-N,N-diethylcyclopropane-1-carboxamide
Show/Hide
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C13H19BrN2OS
|
1
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| 1 |
IC50 = 29 nM
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CP0393189
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(S)-N-(2,3,5-trichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
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C15H19Cl3N2O
|
1
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| 1 |
IC50 = 29 nM
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CP0420205
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N-(azetidin-3-ylmethyl)-N-[(4-chlorophenyl)methyl]aniline
Show/Hide
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C17H19ClN2
|
1
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| 1 |
IC50 = 29.1 nM
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CP0372744
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1-[4-(4-chloro-2-ethylphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
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C17H21ClN2O
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2
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| 1 |
IC50 = 30 nM
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| 2 |
Ki = 22 nM
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CP0396965
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3-[(2-chlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
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C17H19ClN2O
|
1
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| 1 |
IC50 = 30 nM
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CP0035260
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2-(methylaminomethyl)-1-(2-methylphenoxy)-1,3-dihydroinden-2-ol
Show/Hide
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C18H21NO2
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1
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| 1 |
IC50 = 30 nM
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CP0191953
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2-Methylaminomethyl-1-(2-methyl-benzyl)-indan-2-ol
Show/Hide
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C19H23NO
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1
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| 1 |
IC50 = 30 nM
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CP0526997
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N-methyl-1-[(1R,2S)-1-naphthalen-1-yloxy-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
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C21H21NO
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1
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| 1 |
IC50 = 30 nM
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CP0247289
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N-methyl-1-[(3R,4S)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
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C18H21NO2
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2
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| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 100 nM
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CP0095321
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3-[2-(4-chloro-3-fluorophenyl)-2-(3-chlorophenoxy)ethyl]azetidine
Show/Hide
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C17H16Cl2FNO
|
1
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| 1 |
IC50 = 30 nM
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CP0142616
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3-[2-(4-chloro-3-fluorophenyl)-2-(2-chlorophenoxy)ethyl]azetidine
Show/Hide
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C17H16Cl2FNO
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1
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| 1 |
IC50 = 30.8 nM
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CP0047116
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1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine
Show/Hide
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C21H28N2O
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2
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| 1 |
IC50 = 31 nM
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| 2 |
Ki = 31 nM
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CP0446336
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1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)piperazine
Show/Hide
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C19H21F3N2
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1
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| 1 |
IC50 = 31 nM
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CP0374333
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(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)butyramide
Show/Hide
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C15H20Cl2N2O
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1
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| 1 |
IC50 = 31 nM
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CP0400925
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(S)-N-(2,4-dichlorobenzyl)-3-methyl-N-(pyrrolidin-3-yl)butanamide
Show/Hide
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C16H22Cl2N2O
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1
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| 1 |
IC50 = 31 nM
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CP0431951
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(3R)-3-[(S)-(4-chloro-2-methoxyphenoxy)-phenylmethyl]pyrrolidine
Show/Hide
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C18H20ClNO2
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1
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| 1 |
IC50 = 31.62 nM
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CP0431953
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(3S)-3-[(R)-(4-chlorophenoxy)-phenylmethyl]pyrrolidine
Show/Hide
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C17H18ClNO
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1
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| 1 |
IC50 = 31.62 nM
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CP0156518
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4-(4-chloro-2-methoxyphenoxy)-N,N-dimethyl-3-(methylaminomethyl)benzamide
Show/Hide
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C18H21ClN2O3
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1
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| 1 |
IC50 = 32 nM
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CP0002724
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(2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H18FNO2
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2
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| 1 |
IC50 = 32 nM
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| 2 |
IC50 = 740 nM
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CP0054653
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3-[2-(4-chloro-3-fluorophenyl)-2-(4-fluorophenoxy)ethyl]azetidine
Show/Hide
|
C17H16ClF2NO
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1
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| 1 |
IC50 = 32.5 nM
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CP0037454
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4-(2,4-dichlorophenoxy)-N,N-dimethyl-3-(methylaminomethyl)benzamide
Show/Hide
|
C17H18Cl2N2O2
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1
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| 1 |
IC50 = 33 nM
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CP0496230
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2-[(2-phenylphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C23H24N2O
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1
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| 1 |
IC50 = 33 nM
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CP0095322
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3-[2-(4-chloro-3-fluorophenyl)-2-(4-methylphenoxy)ethyl]azetidine
Show/Hide
|
C18H19ClFNO
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1
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| 1 |
IC50 = 33.1 nM
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CP0380095
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3-[2-(3,4-dichlorophenyl)-2-(2-fluorophenoxy)ethyl]azetidine
Show/Hide
|
C17H16Cl2FNO
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1
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| 1 |
IC50 = 33.5 nM
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CP0386329
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3-[2-(3,4-dichlorophenyl)-2-(4-fluorophenoxy)ethyl]azetidine
Show/Hide
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C17H16Cl2FNO
|
1
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| 1 |
IC50 = 33.7 nM
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CP0411925
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N-(azetidin-3-ylmethyl)-N-[(4-fluorophenyl)methyl]aniline;2,2,2-trifluoroacetic acid
Show/Hide
|
C19H20F4N2O2
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1
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| 1 |
IC50 = 34 nM
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CP0467217
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1-(2-(2-bromophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C18H21BrN2
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1
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| 1 |
IC50 = 35 nM
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CP0457463
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2-[(2,3-dichlorophenoxy)-piperidin-4-ylmethyl]-4-methylpyridine
Show/Hide
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C18H20Cl2N2O
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1
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| 1 |
IC50 = 35 nM
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CP0465775
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N-methyl-1-[(1R,2R)-1-(2-methylphenoxy)-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
|
C18H21NO
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1
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| 1 |
IC50 = 35 nM
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CP0465774
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((3R,4R)-4-(o-tolyloxy)-3,4-dihydro-2H-chromen-3-yl)methanamine
Show/Hide
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C17H19NO2
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2
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| 1 |
IC50 = 35 nM
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| 2 |
IC50 = 46 nM
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CP0471374
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1-[4-(4-chloro-2-methylphenoxy)pyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
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C15H17ClN2O
|
1
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| 1 |
IC50 = 36 nM
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CP0455275
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((3R,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO2
|
1
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| 1 |
IC50 = 36 nM
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CP0433654
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[(1S,2R)-2-(aminomethyl)-1-thiophen-3-ylcyclopropyl]-(2,3-dihydro-1H-isoindol-1-yl)methanone
Show/Hide
|
C17H18N2OS
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1
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| 1 |
IC50 = 37 nM
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CP0443220
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(S)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole-5-carbonitrile
Show/Hide
|
C17H19N3
|
1
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| 1 |
IC50 = 37 nM
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CP0542613
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(R)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C15H20Cl2N2O
|
1
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| 1 |
IC50 = 37 nM
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CP0380098
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3-[2-(3,4-dichlorophenyl)-2-phenoxyethyl]azetidine
Show/Hide
|
C17H17Cl2NO
|
1
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| 1 |
IC50 = 37.2 nM
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CP0339524
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4-(2,4-dichlorophenoxy)-N-methyl-3-(methylaminomethyl)benzamide
Show/Hide
|
C16H16Cl2N2O2
|
1
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| 1 |
IC50 = 38 nM
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CP0382110
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1-(2-(2-ethoxyphenyl)-1-(2-fluorophenyl)ethyl)piperazine
Show/Hide
|
C20H25FN2O
|
1
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| 1 |
IC50 = 38 nM
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CP0471383
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1-[4-(2-bromo-4-chlorophenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C14H14BrClN2O
|
1
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| 1 |
IC50 = 38 nM
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CP0264870
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1-(1-phenyl-2-(2-(trifluoromethoxy)phenyl)ethyl)piperazine
Show/Hide
|
C19H21F3N2O
|
2
|
| 1 |
IC50 = 38 nM
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| 2 |
Ki = 77 nM
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CP0394677
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1-(1,2-diphenylethyl)piperazine
Show/Hide
|
C18H22N2
|
1
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| 1 |
IC50 = 39 nM
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CP0498538
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(S)-N-(2,4-dichlorobenzyl)-3,3-dimethyl-N-(pyrrolidin-3-yl)butanamide
Show/Hide
|
C17H24Cl2N2O
|
1
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| 1 |
IC50 = 39 nM
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CP0204992
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((3S,4S)-4-(2,3-dimethylphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 39 nM
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CP0334500
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(S)-pyrrolidin-3-yl-(tetrahydro-pyran-4-yl)-(2,3,4-trifluoro-benzyl)-amine
Show/Hide
|
C16H21F3N2O
|
1
|
| 1 |
IC50 = 40 nM
|
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CP0156540
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(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide
Show/Hide
|
C15H22N2O
|
1
|
| 1 |
IC50 = 40 nM
|
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CP0530531
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(1R,2R)-2-(aminomethyl)-1-(5-chlorothiophen-2-yl)-N,N-diethylcyclopropane-1-carboxamide
Show/Hide
|
C13H19ClN2OS
|
1
|
| 1 |
IC50 = 40 nM
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CP0434930
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1S,2R-milnacipran
Show/Hide
|
C15H22N2O
|
1
|
| 1 |
IC50 = 40 nM
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CP0488306
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4-(1-benzothiophen-5-yl)-7-fluoro-2-methyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C18H16FNS
|
1
|
| 1 |
IC50 = 41 nM
|
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CP0516870
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8-(ethylamino)-1-methyl-4-[3-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydropyrido[2,3-e][1,4]diazepin-5-one
Show/Hide
|
C25H31N5O2S
|
1
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| 1 |
IC50 = 41 nM
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CP0200777
|
1-[2-(2,4-dichlorophenoxy)phenyl]-N-methylmethanamine
Show/Hide
|
C14H13Cl2NO
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0491635
|
3-[(2,3-dimethylphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0000433
|
2-(tert-Butylamino)-3',4'-dichloropentanophenone
Show/Hide
|
C15H21Cl2NO
|
3
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
| 3 |
Ki = 520 nM
|
|
|
|
CP0510890
|
(1S,2R)-2-(aminomethyl)-N-(2-fluoroprop-2-enyl)-N-methyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C13H17FN2OS
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0379290
|
N-(azetidin-3-ylmethyl)-N-[(3,4-dichlorophenyl)methyl]cyclopentanamine
Show/Hide
|
C16H22Cl2N2
|
1
|
| 1 |
IC50 = 44.8 nM
|
|
|
|
CP0390502
|
1-(2-(2-chlorophenyl)-1-(thiazol-2-yl)ethyl)piperazine
Show/Hide
|
C15H18ClN3S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0455248
|
3-[piperidin-4-yl-[2-(trifluoromethoxy)phenoxy]methyl]pyridine
Show/Hide
|
C18H19F3N2O2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0465772
|
N-methyl-1-[(3R,4S)-4-(2-methylsulfanylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
|
C18H21NO2S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0088935
|
N-(azetidin-3-ylmethyl)-N-[(3,4-dichlorophenyl)methyl]propan-2-amine;hydrochloride
Show/Hide
|
C14H21Cl3N2
|
1
|
| 1 |
IC50 = 45.2 nM
|
|
|
|
CP0064062
|
4-(4-chloro-2-methylphenoxy)-3-(methylaminomethyl)benzamide
Show/Hide
|
C16H17ClN2O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0153253
|
1-[2-(2-chloro-4-fluorophenoxy)phenyl]-N,N-dimethylmethanamine
Show/Hide
|
C15H15ClFNO
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0546033
|
(S)-2-(ethylamino)-9- methyl-6-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C24H30N6O2S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0441579
|
1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H20INO
|
2
|
| 1 |
IC50 = 46.5 nM
|
|
|
| 2 |
Ki = 310 nM
|
|
|
|
CP0485792
|
1-[4-(4-chloro-2-methoxyphenoxy)pyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
|
C15H17ClN2O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0196177
|
N-[[1-(2-benzhydryloxyethyl)piperidin-3-yl]methyl]-3-phenylpropan-1-amine
Show/Hide
|
C30H38N2O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0446507
|
1-(1,4-diphenylbutan-2-yl)piperazine
Show/Hide
|
C20H26N2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0387622
|
2-[(2,3-dichlorophenoxy)-piperidin-4-ylmethyl]-5-methylpyridine
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0493325
|
(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C13H20N2OS
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0285514
|
(2-(3-chlorophenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C15H16ClNO
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 82 nM
|
|
|
|
CP0398451
|
(2-(3-chlorophenylthio)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C15H16ClNS
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0439807
|
4-(3,4-dichlorobenzyl)-3-((methylamino)methyl)benzamide
Show/Hide
|
C16H16Cl2N2O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0418830
|
(3S)-3-[(R)-phenyl-(2,3,5-trichlorophenoxy)methyl]pyrrolidine
Show/Hide
|
C17H16Cl3NO
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0489918
|
3-[(S)-phenyl-[(3R)-pyrrolidin-3-yl]methoxy]benzonitrile
Show/Hide
|
C18H18N2O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0377344
|
(RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piperidine
Show/Hide
|
C15H22ClN
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0394251
|
1-[4-(4-chloro-2-methylphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C15H17ClN2O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0004275
|
propan-2-yl (1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C19H27NO2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0446334
|
1-(2-(3-chlorophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C18H21ClN2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0574682
|
(S)-2-(ethylamino)-9- methyl-6-(3-(3- (methylamino)-1- phenylpropoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0439422
|
2pyrrolidin-1-yl-1-phenylpentan-1-one
Show/Hide
|
C15H21NO
|
2
|
| 1 |
IC50 = 56 nM
|
|
|
| 2 |
Ki = 199 nM
|
|
|
|
CP0360437
|
3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole-5-carbonitrile
Show/Hide
|
C17H19N3
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0372819
|
2-(Aminomethyl)-5-(2'-naphthyl)tetrahydrofuran
Show/Hide
|
C15H17NO
|
2
|
| 1 |
IC50 = 58 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0560474
|
9-methyl-6-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)-2- (trifluoromethyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C23H24F3N5O2S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0480363
|
2-Aminomethyl-5-(p-bromophenyl)tetrahydrofuran
Show/Hide
|
C11H14BrNO
|
2
|
| 1 |
IC50 = 59 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0467796
|
N-[(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]methanesulfonamide
Show/Hide
|
C18H20Cl2N2O2S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0374334
|
(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)propionamide
Show/Hide
|
C14H18Cl2N2O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0287226
|
methyl 2-phenyl-2-piperidin-2-ylacetate
Show/Hide
|
C14H19NO2
|
2
|
| 1 |
IC50 = 61 nM
|
|
|
| 2 |
Ki = 660 nM
|
|
|
|
CP0436268
|
1-(1-phenyl-2-(2-(2,2,2-trifluoroethoxy)phenyl)ethyl)piperazine
Show/Hide
|
C20H23F3N2O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0481728
|
2-Aminomethyl-5-(p-chlorophenyl)tetrahydrofuran
Show/Hide
|
C11H14ClNO
|
2
|
| 1 |
IC50 = 61 nM
|
|
|
| 2 |
Ki = 1106 nM
|
|
|
|
CP0153250
|
4-(4-chloro-2-methoxyphenoxy)-3-(methylaminomethyl)benzamide
Show/Hide
|
C16H17ClN2O3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0495933
|
(S)-N-(2,3-dichlorobenzyl)-3-methyl-N-(pyrrolidin-3-yl)butanamide
Show/Hide
|
C16H22Cl2N2O
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0484077
|
(1S,2R)-2-(aminomethyl)-N-(2-methoxyethyl)-N-prop-2-ynyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H20N2O2S
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0388077
|
(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)cyclobutanecarboxamide
Show/Hide
|
C16H20Cl2N2O
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0437284
|
(1R,2R)-2-(aminomethyl)-1-(1-benzothiophen-2-yl)-N,N-diethylcyclopropane-1-carboxamide
Show/Hide
|
C17H22N2OS
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0322032
|
1-methyl-4-[3-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydropyrido[2,3-e][1,4]diazepin-5-one
Show/Hide
|
C23H26N4O2S
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0213887
|
3-[2-(4-chloro-3-fluorophenyl)-2-(2-methylphenoxy)ethyl]azetidine
Show/Hide
|
C18H19ClFNO
|
1
|
| 1 |
IC50 = 68.6 nM
|
|
|
|
CP0398554
|
4-[3-(3,4-dichlorophenyl)-3-pyrrolidin-1-ylpropyl]morpholine
Show/Hide
|
C17H24Cl2N2O
|
1
|
| 1 |
IC50 = 68.9 nM
|
|
|
|
CP0364816
|
N,N-dimethyl-1-(2-phenoxyphenyl)methanamine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0433895
|
N-[3-[(dimethylamino)methyl]-4-(4-methylsulfanylphenyl)sulfanylphenyl]-N-methylmethanesulfonamide
Show/Hide
|
C18H24N2O2S3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0503533
|
(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)pentanamide
Show/Hide
|
C16H22Cl2N2O
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0224231
|
AMITIFADINE HYDROCHLORIDE
Show/Hide
|
C11H11Cl2N
|
1
|
| 1 |
IC50 = 71.4 nM
|
|
|
|
CP0446335
|
1-(2-(2-ethylphenyl)-1-phenylethyl)piperazine
Show/Hide
|
C20H26N2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0444661
|
(1S,3S)-N-methyl-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C17H19NO
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0461242
|
2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile
Show/Hide
|
C19H21N3
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0036757
|
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Show/Hide
|
C19H24N2
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0499692
|
1-(2-(2-chlorophenyl)-1-(pyridin-3-yl)ethyl)piperazine
Show/Hide
|
C17H20ClN3
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0360773
|
2-(aminomethyl)-1-(2-methylphenoxy)-1,3-dihydroinden-2-ol
Show/Hide
|
C17H19NO2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0422637
|
((3S,4S)-4-(2-fluorophenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18FNO2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0509962
|
(1R,2R)-2-(aminomethyl)-N,N-diethyl-1-(thiophen-2-yl)cyclopropanecarboxamide
Show/Hide
|
C13H20N2OS
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0486696
|
1-(2-(2-chlorophenyl)-1-phenylethyl)-1,4-diazepane
Show/Hide
|
C19H23ClN2
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0096208
|
(1S,2R)-2-(aminomethyl)-1-(o-tolyloxy)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C17H19NO2
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0064066
|
4-(4-chloro-2-methoxyphenoxy)-N-methyl-3-(methylaminomethyl)benzamide
Show/Hide
|
C17H19ClN2O3
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0285513
|
1-[2-(4-chloro-2-methoxyphenoxy)phenyl]-N-methylmethanamine
Show/Hide
|
C15H16ClNO2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0384759
|
(R)-N-isobutyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C19H26N2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0384760
|
(S)-N-butyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C19H26N2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0460620
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(4-fluorophenyl)piperazine
Show/Hide
|
C27H29FN6
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0403298
|
1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H20INO
|
2
|
| 1 |
IC50 = 81 nM
|
|
|
| 2 |
Ki = 670 nM
|
|
|
|
CP0446508
|
1-(2-(2,6-dichlorophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C18H20Cl2N2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0170877
|
1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H20BrNO
|
2
|
| 1 |
IC50 = 83 nM
|
|
|
| 2 |
Ki = 386 nM
|
|
|
|
CP0432006
|
1-[4-(4-chloro-2-methoxyphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C15H17ClN2O2
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0064063
|
4-(2,4-dichlorophenoxy)-3-(methylaminomethyl)benzamide
Show/Hide
|
C15H14Cl2N2O2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0498768
|
3-[(2,5-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0471372
|
1-[4-(2-bromo-4-chlorophenoxy)pyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C13H12BrClN2O
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0051444
|
1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methylmethanamine
Show/Hide
|
C14H19Cl2N
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0511408
|
1-[4-(4-chloro-2-ethylphenoxy)pyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C15H17ClN2O
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0417879
|
1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one
Show/Hide
|
C13H16ClNO
|
2
|
| 1 |
IC50 = 86 nM
|
|
|
| 2 |
Ki = 1800 nM
|
|
|
|
CP0170659
|
1-(4-hydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H21NO2
|
2
|
| 1 |
IC50 = 86.7 nM
|
|
|
| 2 |
Ki = 1290 nM
|
|
|
|
CP0041678
|
(2-Benzhydryloxy-ethyl)-(1-benzyl-piperidin-4-yl)-amine
Show/Hide
|
C27H32N2O
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0414655
|
N-(azetidin-3-ylmethyl)-N-(naphthalen-2-ylmethyl)aniline
Show/Hide
|
C21H22N2
|
1
|
| 1 |
IC50 = 87.9 nM
|
|
|
|
CP0403195
|
1-(4-methylphenyl)-2-pyrrolidin-1-yl-pent-4-ene-1-one
Show/Hide
|
C16H21NO
|
2
|
| 1 |
IC50 = 88 nM
|
|
|
| 2 |
Ki = 1400 nM
|
|
|
|
CP0446337
|
1-(1-phenyl-2-o-tolylethyl)piperazine
Show/Hide
|
C19H24N2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0498766
|
3-[(2-ethylphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0474509
|
2-Aminomethyl-5-(p-methoxyphenyl)tetrahydrofuran
Show/Hide
|
C12H17NO2
|
2
|
| 1 |
IC50 = 92 nM
|
|
|
| 2 |
Ki = 2013 nM
|
|
|
|
CP0423029
|
(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)pivalamide
Show/Hide
|
C16H22Cl2N2O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0403192
|
1-(4-furan-2-ylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C19H23NO2
|
2
|
| 1 |
IC50 = 93 nM
|
|
|
| 2 |
Ki = 95 nM
|
|
|
|
CP0389390
|
US9085531, 100
Show/Hide
|
C22H24N2OS
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0393800
|
1-(2-(2-chlorophenyl)-1-(4-fluorophenyl)ethyl)piperazine
Show/Hide
|
C18H20ClFN2
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0438990
|
(S)-N-(2,4-dichlorobenzyl)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0399341
|
((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-3-yl)methanamine
Show/Hide
|
C17H19NO2
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0209068
|
(2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piperidin-3-ylmethyl]-amine
Show/Hide
|
C30H38N2O
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0560475
|
1-methyl-4-[3-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-1,4-diazepan-5-one
Show/Hide
|
C20H27N3O2S
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0503537
|
(S)-N-(2-chloro-4-fluorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C15H20ClFN2O
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0428786
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-(3-phenylpropyl)piperazine
Show/Hide
|
C31H38N6
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0440578
|
(1S,2R)-2-(aminomethyl)-N-methyl-N-prop-2-enyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C13H18N2OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0407224
|
1-(2-(2,3-dichlorophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C18H20Cl2N2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0352147
|
N-methyl-1-[(1S,2R)-1-(2-methylphenoxy)-1,2,3,4-tetrahydronaphthalen-2-yl]methanamine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0002366
|
(2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H18ClNO2
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 9900 nM
|
|
|
|
CP0396967
|
3-[piperidin-4-yl-[2-(trifluoromethyl)phenoxy]methyl]pyridine
Show/Hide
|
C18H19F3N2O
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0439374
|
(4S,6S)-3-Butyl-4-p-tolyl-1-aza-tricyclo[4.4.0.0*2,8*]decane
Show/Hide
|
C19H27N
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0553322
|
1,8-dimethyl-4-[3-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydropyrido[2,3-e][1,4]diazepin-5-one
Show/Hide
|
C24H28N4O2S
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0398584
|
(1R,3S)-3-p-Tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-one
Show/Hide
|
C16H19NO
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0452745
|
(1S,2R)-2-(aminomethyl)-N-methyl-N-prop-2-ynyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C13H16N2OS
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0063854
|
1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine
Show/Hide
|
C28H32F2N2O
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 1460 nM
|
|
|
|
CP0494612
|
(S)-N-(2-chlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C15H21ClN2O
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0000078
|
(+/-)2-(3,4-Dichlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H17Cl2NO2
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0502811
|
N'-[2-[bis(4-fluorophenyl)methoxy]ethyl]-N-(2-phenylethyl)propane-1,3-diamine
Show/Hide
|
C26H30F2N2O
|
2
|
| 1 |
IC50 = 116 nM
|
|
|
| 2 |
Ki = 82 nM
|
|
|
|
CP0374860
|
1-(2-(2,5-dichlorophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C18H20Cl2N2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0390501
|
1-(2-(2-chlorophenyl)-1-(thiazol-5-yl)ethyl)piperazine
Show/Hide
|
C15H18ClN3S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0036832
|
4-[(Naphthalen-1-yloxy)-phenyl-methyl]-piperidine
Show/Hide
|
C22H23NO
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0378737
|
(+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)propan-1-amine
Show/Hide
|
C15H21Cl2N
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0002120
|
cyclobutyl (1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C20H27NO2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0393801
|
1-(2-(2-chlorophenyl)-1-(2-fluorophenyl)ethyl)piperazine
Show/Hide
|
C18H20ClFN2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0461241
|
1-(2-(3-methoxyphenyl)-1-phenylethyl)piperazine
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0468493
|
4-(3,4-dichlorobenzyl)-3-((methylamino)methyl)benzenesulfonamide
Show/Hide
|
C15H16Cl2N2O2S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0480599
|
N-benzyl-N-(naphthalen-2-ylmethyl)azetidin-3-amine
Show/Hide
|
C21H22N2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0001153
|
2-(tert-Butylamino)-3',4'-dichlorobutyrophenone
Show/Hide
|
C14H19Cl2NO
|
3
|
| 1 |
IC50 = 135 nM
|
|
|
| 2 |
IC50 = 389 nM
|
|
|
| 3 |
Ki = 2240 nM
|
|
|
|
CP0001155
|
2-(N-Pyrrolidinyl)-3'-fluoropropiophenone
Show/Hide
|
C14H18FNO
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0913543
|
3-(3,4-Dichlorophenyl)-N,N-diethyl-3-(pyrrolidin-1-yl)propan-1-amine
Show/Hide
|
C17H26Cl2N2
|
1
|
| 1 |
IC50 = 136.4 nM
|
|
|
|
CP0377418
|
((3S,4S)-4-(2-chlorophenoxy)isothiochroman-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18ClNOS
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0440600
|
((3R,4S)-4-(2-chlorophenoxy)isochroman-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18ClNO2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0375527
|
N'-(2-benzhydryloxyethyl)-N,N'-dimethyl-N-(3-phenylpropyl)propane-1,3-diamine
Show/Hide
|
C29H38N2O
|
2
|
| 1 |
IC50 = 143 nM
|
|
|
| 2 |
Ki = 30 nM
|
|
|
|
CP0048099
|
1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane
Show/Hide
|
C11H11Cl2N
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0369354
|
(R)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine
Show/Hide
|
C18H28N2O
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0492693
|
((3S,4R)-4-(2-chlorophenoxy)thiochroman-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18ClNOS
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0399589
|
(1R,2R)-2-(aminomethyl)-N,N-diethyl-1-(5-fluoro-1-benzothiophen-2-yl)cyclopropane-1-carboxamide
Show/Hide
|
C17H21FN2OS
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0456134
|
(1S,3S)-N,N-dimethyl-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0485064
|
(1R,3S)-N,N-dimethyl-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0002308
|
(2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H18BrNO2
|
2
|
| 1 |
IC50 = 150 nM
|
|
|
| 2 |
IC50 = 920 nM
|
|
|
|
CP0000198
|
(2S,3S)-2-(3,5-Difluorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H17F2NO2
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0894654
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)-[1,1'-biphenyl]-4-carboxamide
Show/Hide
|
C28H32N2O
|
1
|
| 1 |
IC50 = 153 nM
|
|
|
|
CP0288368
|
1-[2-(2-chloro-4-methoxyphenoxy)phenyl]-N-methylmethanamine
Show/Hide
|
C15H16ClNO2
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0511466
|
1-[3-(1-benzothiophen-3-yl)-3-pyrrolidin-1-ylpropyl]-4-benzyl-3,6-dihydro-2H-pyridine
Show/Hide
|
C27H32N2S
|
1
|
| 1 |
IC50 = 157.3 nM
|
|
|
|
CP0485793
|
1-[4-(2,4-dichlorophenoxy)pyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C13H12Cl2N2O
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0486957
|
(2S,4S)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0049036
|
1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine
Show/Hide
|
C28H34N2O
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0150166
|
1-(2-benzhydryloxyethyl)-N-[2-(4-fluorophenyl)ethyl]piperidin-4-amine
Show/Hide
|
C28H33FN2O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0433655
|
(1S,2R)-2-(aminomethyl)-1-(1-benzothiophen-3-yl)-N,N-diethylcyclopropane-1-carboxamide
Show/Hide
|
C17H22N2OS
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0004041
|
(2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorpholin-2-ol
Show/Hide
|
C14H20ClNO2
|
2
|
| 1 |
IC50 = 170 nM
|
|
|
| 2 |
IC50 = 415 nM
|
|
|
|
CP0441625
|
1-(4-fluorophenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H20FNO
|
2
|
| 1 |
IC50 = 171 nM
|
|
|
| 2 |
Ki = 830 nM
|
|
|
|
CP0145782
|
N-[(4-chlorophenyl)methyl]-N-(2-fluorophenyl)azetidin-3-amine
Show/Hide
|
C16H16ClFN2
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0130302
|
1-(2-benzhydryloxyethyl)-N-methyl-N-(3-phenylpropyl)piperidin-4-amine
Show/Hide
|
C30H38N2O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0037455
|
(2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C15H16ClNO
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
IC50 = 256 nM
|
|
|
|
CP0465777
|
N-methyl-1-[(1R,2R)-1-(2-methylphenoxy)-1,2,3,4-tetrahydronaphthalen-2-yl]methanamine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0411813
|
4-(1-benzothiophen-5-yl)-2-methyl-3,4-dihydro-1H-isoquinoline-7-carbonitrile
Show/Hide
|
C19H16N2S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0571508
|
2-(ethylamino)-9- methyl-6-(3-((3- (methylamino)-1- phenylpropoxy)methyl) phenyl)-6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 = 184 nM
|
|
|
|
CP0035807
|
Cocaine
Show/Hide
|
C17H21NO4
|
26
|
| 1 |
IC50 = 186 nM
|
|
|
| 2 |
IC50 = 192 nM
|
|
|
| 3 |
IC50 = 210 nM
|
|
|
| 4 |
IC50 = 221 nM
|
|
|
| 5 |
IC50 = 230 nM
|
|
|
| 6 |
IC50 = 232 nM
|
|
|
| 7 |
IC50 = 233 nM
|
|
|
| 8 |
IC50 = 378 nM
|
|
|
| 9 |
IC50 = 385 nM
|
|
|
| 10 |
IC50 = 835 nM
|
|
|
| 11 |
IC50 = 1281 nM
|
|
|
| 12 |
IC50 = 1900 nM
|
|
|
| 13 |
IC50 = 6309.57 nM
|
|
|
| 14 |
Ki = 500 nM
|
|
|
| 15 |
Ki = 645 nM
|
|
|
| 16 |
Ki = 830 nM
|
|
|
| 17 |
Ki = 1115 nM
|
|
|
| 18 |
Ki = 1116 nM
|
|
|
| 19 |
Ki = 1257 nM
|
|
|
| 20 |
Ki = 1770 nM
|
|
|
| 21 |
Ki = 1940 nM
|
|
|
| 22 |
Ki = 2150 nM
|
|
|
| 23 |
Ki = 2357 nM
|
|
|
| 24 |
Ki = 2377 nM
|
|
|
| 25 |
Ki = 2410 nM
|
|
|
| 26 |
Ki = 10700 nM
|
|
|
|
CP0345009
|
(R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propylamine
Show/Hide
|
C17H17NOS
|
2
|
| 1 |
IC50 = 188 nM
|
|
|
| 2 |
Ki = 953 nM
|
|
|
|
CP0341416
|
N-[[1-(2-benzhydryloxyethyl)piperidin-3-yl]methyl]-2-(4-fluorophenyl)ethanamine
Show/Hide
|
C29H35FN2O
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0456136
|
(2R,4R)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0404555
|
N-[3-[2-[bis(4-fluorophenyl)methoxy]ethylamino]propyl]-2-phenylacetamide
Show/Hide
|
C26H28F2N2O2
|
2
|
| 1 |
IC50 = 192 nM
|
|
|
| 2 |
Ki = 477 nM
|
|
|
|
CP0076638
|
(2-Benzhydryloxy-ethyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-amine
Show/Hide
|
C29H35FN2O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0214425
|
(2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piperidin-4-yl]-amine
Show/Hide
|
C30H38N2O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0433656
|
[(1S,2R)-2-(aminomethyl)-1-thiophen-3-ylcyclopropyl]-(3,4-dihydro-2H-pyridin-1-yl)methanone
Show/Hide
|
C14H18N2OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0377305
|
(S)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile
Show/Hide
|
C16H16N2O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0497972
|
(2-(3,4-dichlorobenzyl)phenyl)-N-methylmethanamine
Show/Hide
|
C15H15Cl2N
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0262534
|
N-methyl-1-[(3S,4R)-4-(2-methylphenoxy)-3,4-dihydro-2H-chromen-3-yl]methanamine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0375181
|
(2R,4S)-N-methyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0575277
|
(R)-2-(ethylamino)-9- methyl-6-(3-(3- (methylamino)-1- phenylpropoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0860673
|
N-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethylamino}-butyl)-2-phenyl-acetamide
Show/Hide
|
C26H28F2N2O2
|
2
|
| 1 |
IC50 = 205 nM
|
|
|
| 2 |
Ki = 545 nM
|
|
|
|
CP0946192
|
3-(3,4-Dichlorophenyl)-N,N-dimethyl-3-(pyrrolidin-1-yl)propan-1-amine
Show/Hide
|
C15H22Cl2N2
|
1
|
| 1 |
IC50 = 205.7 nM
|
|
|
|
CP0405089
|
N'-(2-benzhydryloxyethyl)-N,N'-dimethyl-N-(2-phenylethyl)propane-1,3-diamine
Show/Hide
|
C28H36N2O
|
2
|
| 1 |
IC50 = 210 nM
|
|
|
| 2 |
Ki = 194 nM
|
|
|
|
CP0417775
|
2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran
Show/Hide
|
C15H17NO
|
2
|
| 1 |
IC50 = 210 nM
|
|
|
| 2 |
Ki = 1494 nM
|
|
|
|
CP0450978
|
(S)-8-(ethylamino)-1- methyl-4-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)- 1,2,3,4-tetrahydro-5H- pyrido[4,3- e][1,4]diazepin-5-one
Show/Hide
|
C25H31N5O2S
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0575280
|
1-methyl-4-[3-[3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydropyrido[3,2-e][1,4]diazepin-5-one
Show/Hide
|
C23H26N4O2S
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0428438
|
3-[piperidin-4-yl-(2,3,5-trichlorophenoxy)methyl]pyridine
Show/Hide
|
C17H17Cl3N2O
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0432678
|
1-phenyl-1-(piperidin-2-yl)propan-2-one
Show/Hide
|
C14H19NO
|
2
|
| 1 |
IC50 = 220 nM
|
|
|
| 2 |
Ki = 2700 nM
|
|
|
|
CP0579759
|
2-(dimethylamino)-9- methyl-6-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C24H30N6O2S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0000311
|
1-(3-chlorophenyl)-2-(cyclopentylamino)propan-1-one
Show/Hide
|
C14H18ClNO
|
3
|
| 1 |
IC50 = 221 nM
|
|
|
| 2 |
IC50 > 100 nM
|
|
|
| 3 |
Ki = 5700 nM
|
|
|
|
CP0433683
|
(R)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)propionamide
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
IC50 = 224 nM
|
|
|
|
CP0119082
|
1-(2-benzhydryloxyethyl)-N-(3-phenylpropyl)piperidin-4-amine
Show/Hide
|
C29H36N2O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0526766
|
((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chromen-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18ClNO2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0161475
|
1-(4-methoxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO2
|
2
|
| 1 |
IC50 = 235 nM
|
|
|
| 2 |
Ki = 2600 nM
|
|
|
|
CP0860019
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)-6-methoxy-2-naphthamide
Show/Hide
|
C27H32N2O2
|
1
|
| 1 |
IC50 = 238 nM
|
|
|
|
CP0440598
|
((3R,4S)-4-(2-ethoxyphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0000058
|
(2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H18ClNO2
|
2
|
| 1 |
IC50 = 241 nM
|
|
|
| 2 |
IC50 = 1200 nM
|
|
|
|
CP0485791
|
1-[4-(4-chloro-2-methylphenoxy)pyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C14H15ClN2O
|
1
|
| 1 |
IC50 = 246 nM
|
|
|
|
CP0490046
|
3-(1-benzothiophen-3-yl)-N,N-dimethyl-3-pyrrolidin-1-ylpropan-1-amine
Show/Hide
|
C17H24N2S
|
1
|
| 1 |
IC50 = 249.9 nM
|
|
|
|
CP0516338
|
1-[4-(2-methoxy-4-methylphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C16H20N2O2
|
1
|
| 1 |
IC50 = 257 nM
|
|
|
|
CP0415484
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]naphthalene-2-carboxamide
Show/Hide
|
C24H25Cl2N3O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0099047
|
2-pyrrolidin-1-yl-1-(4-thiophen-2-yl-phenyl)pentan-1-one
Show/Hide
|
C19H23NOS
|
2
|
| 1 |
IC50 = 263 nM
|
|
|
| 2 |
Ki = 370 nM
|
|
|
|
CP0059793
|
3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid (3-{[3-(4-chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carbonyl]-amino}-propyl)-amide
Show/Hide
|
C33H42Cl2N4O2
|
2
|
| 1 |
IC50 = 266 nM
|
|
|
| 2 |
Ki = 2970 nM
|
|
|
|
CP0877359
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)-3,5-dichlorobenzamide
Show/Hide
|
C22H26Cl2N2O
|
1
|
| 1 |
IC50 = 267 nM
|
|
|
|
CP0877357
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)-1H-indole-2-carboxamide
Show/Hide
|
C24H29N3O
|
1
|
| 1 |
IC50 = 268 nM
|
|
|
|
CP0411923
|
N-cyclohexyl-N-(naphthalen-2-ylmethyl)azetidin-3-amine
Show/Hide
|
C20H26N2
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0459848
|
(5S,8S)-5-(3,4-dichlorophenyl)-N,N-dimethyl-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
Show/Hide
|
C20H22Cl2N2O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0452743
|
(1R,2R)-2-(aminomethyl)-N,N-diethyl-1-(3,4,5-trichlorothiophen-2-yl)cyclopropane-1-carboxamide
Show/Hide
|
C13H17Cl3N2OS
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0529752
|
1-(2-(2-(methylsulfonyl)phenyl)-1-phenylethyl)piperazine
Show/Hide
|
C19H24N2O2S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0879013
|
N-(2-(4-Benzylpiperidin-1-yl)ethyl)quinoline-2-carboxamide
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0397985
|
N'-(2-benzhydryloxyethyl)-N-[2-(4-fluorophenyl)ethyl]-N,N'-dimethylethane-1,2-diamine
Show/Hide
|
C27H33FN2O
|
2
|
| 1 |
IC50 = 279 nM
|
|
|
| 2 |
Ki = 370 nM
|
|
|
|
CP0394254
|
1-[4-(4-chloro-2-methoxyphenoxy)pyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C14H15ClN2O2
|
1
|
| 1 |
IC50 = 282 nM
|
|
|
|
CP0130783
|
(2-(3,4-dichlorophenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C15H15Cl2NO
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0067008
|
N-methyl-1-(1-naphthalen-2-ylcyclohexyl)methanamine
Show/Hide
|
C18H23N
|
1
|
| 1 |
IC50 = 295 nM
|
|
|
|
CP0448967
|
(1R,3S,5S)-5-Methyl-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-ol
Show/Hide
|
C17H23NO
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0397376
|
N-[2-[2-[bis(4-fluorophenyl)methoxy]ethylamino]ethyl]-2-(4-fluorophenyl)acetamide
Show/Hide
|
C25H25F3N2O2
|
2
|
| 1 |
IC50 = 299 nM
|
|
|
| 2 |
Ki = 844 nM
|
|
|
|
CP0153251
|
1-[2-(2-chloro-4-fluorophenoxy)phenyl]-N-methylmethanamine
Show/Hide
|
C14H13ClFNO
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0446494
|
3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile
Show/Hide
|
C19H21N3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0299186
|
(1S,2R)-1-(2-(hydroxymethyl)phenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0387768
|
(S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)-tetrahydro-2H-pyran-4-carboxamide
Show/Hide
|
C17H22Cl2N2O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0449720
|
(5R,8R)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C17H18Cl2N2O2S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0459849
|
(5S,8R)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C17H18Cl2N2O2S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0001503
|
3-(4-chlorophenyl)-5-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,2-oxazole
Show/Hide
|
C24H25ClN2O
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0170879
|
N-[4-(2-pyrrolidin-1-ylpentanoyl)phenyl]acetamide
Show/Hide
|
C17H24N2O2
|
2
|
| 1 |
IC50 = 317 nM
|
|
|
| 2 |
Ki = 4000 nM
|
|
|
|
CP0392001
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
Show/Hide
|
C31H36N6
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0476506
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-benzylpiperazine
Show/Hide
|
C29H34N6
|
1
|
| 1 |
IC50 = 323 nM
|
|
|
|
CP0858343
|
3-(2,4-Difluorophenyl)-N-methyl-3-morpholinopropan-1-amine
Show/Hide
|
C14H20F2N2O
|
1
|
| 1 |
IC50 = 327.9 nM
|
|
|
|
CP0451709
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-(2-phenylethyl)piperazine
Show/Hide
|
C30H36N6
|
1
|
| 1 |
IC50 = 329 nM
|
|
|
|
CP0119306
|
N-(naphthalen-2-ylmethyl)-N-phenylazetidin-3-amine;hydrochloride
Show/Hide
|
C20H21ClN2
|
1
|
| 1 |
IC50 = 333 nM
|
|
|
|
CP0530666
|
1-(2-(2-ethoxyphenyl)-1-(thiazol-2-yl)ethyl)piperazine
Show/Hide
|
C17H23N3OS
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0573055
|
1-methyl-4-[3-[3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydropyrido[3,4-e][1,4]diazepin-5-one
Show/Hide
|
C23H26N4O2S
|
1
|
| 1 |
IC50 = 341 nM
|
|
|
|
CP0772168
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)-2-naphthamide
Show/Hide
|
C26H30N2O
|
1
|
| 1 |
IC50 = 342 nM
|
|
|
|
CP0372821
|
2-(2'-Aminoethyl)-5-benzyltetrahydrofuran
Show/Hide
|
C13H19NO
|
2
|
| 1 |
IC50 = 347 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0209018
|
N-[[1-(2-benzhydryloxyethyl)piperidin-3-yl]methyl]-2-(4-fluorophenyl)-N-methylethanamine
Show/Hide
|
C30H37FN2O
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0869955
|
1-(4-methylphenyl)-2-pyrrolidin-1-yl-pent-4-yn-1-one
Show/Hide
|
C16H19NO
|
2
|
| 1 |
IC50 = 350 nM
|
|
|
| 2 |
Ki = 4100 nM
|
|
|
|
CP0559854
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2-fluorophenyl)piperazine
Show/Hide
|
C27H29FN6
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0439181
|
(S)-3,4-dichloro-2-methyl-N-neopentyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C17H24Cl2N2O
|
1
|
| 1 |
IC50 = 357 nM
|
|
|
|
CP0377721
|
2-(Aminomethyl)-5-phenethyltetrahydrofuran
Show/Hide
|
C13H19NO
|
2
|
| 1 |
IC50 = 360 nM
|
|
|
| 2 |
Ki = 2736 nM
|
|
|
|
CP0388252
|
2-(N-tert-Butylamino)-3'-chlorophenyl-4-methylpentanophenone
Show/Hide
|
C16H24ClNO
|
2
|
| 1 |
IC50 = 360 nM
|
|
|
| 2 |
Ki = 2300 nM
|
|
|
|
CP0428894
|
(S)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)methanesulfonamide
Show/Hide
|
C16H20N2O2S
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0262533
|
((3R,4R)-4-(2-chlorophenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C17H18ClNO2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0398788
|
N-methyl-1-[(3S,4S)-4-(2-methylphenoxy)-3,4-dihydro-2H-chromen-3-yl]methanamine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0000907
|
2-(N-tert-Butylamino)-3'-chloropentanophenone
Show/Hide
|
C15H22ClNO
|
3
|
| 1 |
IC50 = 370 nM
|
|
|
| 2 |
IC50 = 472 nM
|
|
|
| 3 |
Ki = 1171 nM
|
|
|
|
CP0848012
|
3-(5-Chloro-6-methoxynaphthalen-2-yl)-N,N-dimethyl-3-(pyrrolidin-1-yl)propan-1-amine
Show/Hide
|
C20H27ClN2O
|
1
|
| 1 |
IC50 = 373.5 nM
|
|
|
|
CP0417773
|
2-Aminoethyl-5-(4'-fluoro-3'-methylphenethyl)tetrahydrofuran
Show/Hide
|
C15H22FNO
|
2
|
| 1 |
IC50 = 374 nM
|
|
|
| 2 |
Ki = 882 nM
|
|
|
|
CP0414875
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(3-chlorophenyl)piperazine
Show/Hide
|
C25H34ClN3
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0439376
|
(R)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole-5-carbonitrile
Show/Hide
|
C17H19N3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0433733
|
1-[4-(4-chloro-2-ethoxyphenoxy)pyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C15H17ClN2O2
|
1
|
| 1 |
IC50 = 394 nM
|
|
|
|
CP0475603
|
N-[2-[2-[bis(4-fluorophenyl)methoxy]ethylamino]ethyl]-2-phenylacetamide
Show/Hide
|
C25H26F2N2O2
|
2
|
| 1 |
IC50 = 399 nM
|
|
|
| 2 |
Ki = 604 nM
|
|
|
|
CP0476508
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2-phenylethyl)piperazine
Show/Hide
|
C29H34N6
|
1
|
| 1 |
IC50 = 399.5 nM
|
|
|
|
CP0373898
|
2-(N-tert-Butylamino)-3'-chlorohexanophenone
Show/Hide
|
C16H24ClNO
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
Ki = 3190 nM
|
|
|
|
CP0422647
|
N-methyl-1-[(1R,2R)-1-naphthalen-1-yloxy-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
|
C21H21NO
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0469678
|
3-[(3-ethylphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 = 404 nM
|
|
|
|
CP0456846
|
(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0000080
|
(2S,3S)-2-(Naphthalen-1-yl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C23H25NO2
|
1
|
| 1 |
IC50 = 411 nM
|
|
|
|
CP0417584
|
N-methyl-1-[(3R,4S)-4-(2-methylphenoxy)-3,4-dihydro-2H-chromen-3-yl]methanamine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0957357
|
4-Benzyl-1-(3-(3,4-dichlorophenyl)-3-(pyrrolidin-1-yl)propyl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C25H30Cl2N2
|
1
|
| 1 |
IC50 = 425.7 nM
|
|
|
|
CP0950659
|
3-(3,4-Dichlorophenyl)-N,N-dimethyl-3-(piperazin-1-yl)propan-1-amine
Show/Hide
|
C15H23Cl2N3
|
1
|
| 1 |
IC50 = 427.6 nM
|
|
|
|
CP0320329
|
1-[2-(4-chloro-2-fluorophenoxy)phenyl]-N-methylmethanamine
Show/Hide
|
C14H13ClFNO
|
1
|
| 1 |
IC50 = 429 nM
|
|
|
|
CP0431535
|
4-(3,4-dichlorobenzyl)-3-((dimethylamino)methyl)benzamide
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0465771
|
N-methyl-1-[(3R,4R)-4-(2-methylphenoxy)-3,4-dihydro-2H-thiochromen-3-yl]methanamine
Show/Hide
|
C18H21NOS
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0486958
|
(2S,4R)-N,N-dimethyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0439379
|
(5S,8S)-5-(3,4-dichlorophenyl)-N-methyl-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
Show/Hide
|
C19H20Cl2N2O
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0000055
|
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
Show/Hide
|
C13H18ClNO
|
4
|
| 1 |
IC50 = 443 nM
|
|
|
| 2 |
IC50 = 1850 nM
|
|
|
| 3 |
IC50 = 3240 nM
|
|
|
| 4 |
Ki = 6970 nM
|
|
|
|
CP0316466
|
(S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propylamine
Show/Hide
|
C17H17NOS
|
2
|
| 1 |
IC50 = 445 nM
|
|
|
| 2 |
Ki = 2402 nM
|
|
|
|
CP0441766
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methylsulfinylmethyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C19H21Cl2NOS
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0531989
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(4-chlorophenyl)piperazine
Show/Hide
|
C27H29ClN6
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0900373
|
N-(2-(4-Benzylpiperidin-1-yl)ethyl)-[1,1'-biphenyl]-4-carboxamide
Show/Hide
|
C27H30N2O
|
1
|
| 1 |
IC50 = 472 nM
|
|
|
|
CP0664484
|
3-(3,4-Dichlorophenyl)-N,N-dimethyl-3-morpholinopropan-1-amine
Show/Hide
|
C15H22Cl2N2O
|
1
|
| 1 |
IC50 = 477.5 nM
|
|
|
|
CP0090151
|
N-cyclopropyl-N-[(3,4-dichlorophenyl)methyl]azetidin-3-amine
Show/Hide
|
C13H16Cl2N2
|
1
|
| 1 |
IC50 = 479 nM
|
|
|
|
CP0526907
|
((3R,4S)-4-(2-methoxyphenoxy)-3,4-dihydro-1H-isochromen-3-yl)-N-methylmethanamine
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0497160
|
2-[(2R,5S)-5-[2-(5-fluoro-2-methoxyphenyl)ethyl]oxolan-2-yl]ethanamine
Show/Hide
|
C15H22FNO2
|
2
|
| 1 |
IC50 = 481 nM
|
|
|
| 2 |
Ki = 2440 nM
|
|
|
|
CP0372934
|
tetrahydrofuranyl ethylamine, 14
Show/Hide
|
C15H22FNO2
|
2
|
| 1 |
IC50 = 481 nM
|
|
|
| 2 |
Ki = 2440 nM
|
|
|
|
CP0181156
|
3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid (8-{[3-(4-chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carbonyl]-amino}-octyl)-amide
Show/Hide
|
C38H52Cl2N4O2
|
2
|
| 1 |
IC50 = 487 nM
|
|
|
| 2 |
Ki = 830 nM
|
|
|
|
CP0543155
|
3-(1-benzothiophen-2-yl)-N,N-dimethyl-3-pyrrolidin-1-ylpropan-1-amine
Show/Hide
|
C17H24N2S
|
1
|
| 1 |
IC50 = 495 nM
|
|
|
|
CP0540785
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H32N6O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0468511
|
3-((dimethylamino)methyl)-N,N-dimethyl-4-(4-(trifluoromethoxy)phenoxy)benzamide
Show/Hide
|
C19H21F3N2O3
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0482409
|
5-[(1R,2S)-2-(methylaminomethyl)cyclopentyl]-1H-indole-3-carbonitrile
Show/Hide
|
C16H19N3
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0430174
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2,6-difluorophenyl)piperazine
Show/Hide
|
C27H28F2N6
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0088934
|
N-[(4-chlorophenyl)methyl]-N-cyclohexylazetidin-3-amine
Show/Hide
|
C16H23ClN2
|
1
|
| 1 |
IC50 = 518 nM
|
|
|
|
CP0492092
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-benzylpiperidine
Show/Hide
|
C29H33N5
|
1
|
| 1 |
IC50 = 519 nM
|
|
|
|
CP0440511
|
(1R,4S)-N-methyl-4-(2-methylphenoxy)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0492094
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-benzylpiperazine
Show/Hide
|
C28H32N6
|
1
|
| 1 |
IC50 = 521 nM
|
|
|
|
CP0000056
|
(2S,3S)-2-(4-Chlorophenyl)-3,4,5,5-tetramethylmorpholin-2-ol
Show/Hide
|
C14H20ClNO2
|
1
|
| 1 |
IC50 = 527 nM
|
|
|
|
CP0444670
|
N-[3-[(dimethylamino)methyl]-4-(4-methylsulfanylphenyl)sulfanylphenyl]methanesulfonamide
Show/Hide
|
C17H22N2O2S3
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0414874
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(4-chlorophenyl)piperazine
Show/Hide
|
C25H34ClN3
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0161477
|
1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H20N2O3
|
2
|
| 1 |
IC50 = 531 nM
|
|
|
| 2 |
Ki = 2690 nM
|
|
|
|
CP0152573
|
N-(3-chlorophenyl)-N-(naphthalen-2-ylmethyl)azetidin-3-amine
Show/Hide
|
C20H19ClN2
|
1
|
| 1 |
IC50 = 531 nM
|
|
|
|
CP0386598
|
(5S,8S)-5-(3,4-dichlorophenyl)-N-(2-hydroxyethyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C19H22Cl2N2O3S
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0001471
|
(2S,3S)-2-Phenyl-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H19NO2
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0493329
|
(1R,2R)-2-(aminomethyl)-1-(4,5-dichlorothiophen-2-yl)-N,N-diethylcyclopropane-1-carboxamide
Show/Hide
|
C13H18Cl2N2OS
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0428292
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C25H33Cl2N3
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0411360
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(3-phenylpropyl)piperazine
Show/Hide
|
C30H36N6
|
1
|
| 1 |
IC50 = 568.9 nM
|
|
|
|
CP0001154
|
2-(N-Pyrrolidinyl)-3'-methylpropiophenone
Show/Hide
|
C15H21NO
|
1
|
| 1 |
IC50 = 577 nM
|
|
|
|
CP0372381
|
2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-(4-nitrophenyl)-1,3-thiazole
Show/Hide
|
C23H22ClN3O2S
|
2
|
| 1 |
IC50 = 582 nM
|
|
|
| 2 |
Ki = 2270 nM
|
|
|
|
CP0398500
|
N-(4-methylphenyl)-N-(naphthalen-2-ylmethyl)azetidin-3-amine
Show/Hide
|
C21H22N2
|
1
|
| 1 |
IC50 = 597 nM
|
|
|
|
CP0428290
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-phenylpiperazine
Show/Hide
|
C25H35N3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0445578
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-pyridin-2-ylpiperazine
Show/Hide
|
C24H25F2N3O
|
2
|
| 1 |
IC50 = 600 nM
|
|
|
| 2 |
IC50 = 602.8 nM
|
|
|
|
CP0571509
|
(R)-2-(ethylamino)-9- methyl-6-(3-(3- (methylamino)-1- (thiophen-2- yl)propoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C24H30N6O2S
|
1
|
| 1 |
IC50 = 601 nM
|
|
|
|
CP0000202
|
2-(N-tert-Butylamino)-3'-chlorobutyrophenone
Show/Hide
|
C14H20ClNO
|
3
|
| 1 |
IC50 = 607 nM
|
|
|
| 2 |
IC50 = 969 nM
|
|
|
| 3 |
Ki = 3195 nM
|
|
|
|
CP0385617
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(4-bromophenyl)piperazine
Show/Hide
|
C25H34BrN3
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0494817
|
(1R,3S)-3-(4-Fluoro-phenyl)-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-one
Show/Hide
|
C15H16FNO
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0372375
|
2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-(4-methoxyphenyl)-1,3-thiazole
Show/Hide
|
C24H25ClN2OS
|
2
|
| 1 |
IC50 = 620 nM
|
|
|
| 2 |
Ki = 1270 nM
|
|
|
|
CP0877393
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)benzo(b)furan-2-carboxamide
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
IC50 = 621 nM
|
|
|
|
CP0377718
|
[(2R,5S)-5-[2-(5-fluoro-2-methoxyphenyl)ethyl]oxolan-2-yl]methanamine
Show/Hide
|
C14H20FNO2
|
2
|
| 1 |
IC50 = 628 nM
|
|
|
| 2 |
Ki = 5993 nM
|
|
|
|
CP0484982
|
(5-fluoro-2-(4-(methylthio)phenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C16H18FNOS
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0485062
|
(1R,4S)-4-(2-methylphenoxy)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C17H19NO
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0086307
|
(+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine
Show/Hide
|
C16H18N2
|
3
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
| 3 |
Ki = 83 nM
|
|
|
|
CP0239872
|
(+)-(S)-amphetamine
Show/Hide
|
C9H13N
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
Ki = 101 nM
|
|
|
|
CP0913544
|
3-(3,4-Dichlorophenyl)-N,N-dimethyl-3-(piperidin-1-yl)propan-1-amine
Show/Hide
|
C16H24Cl2N2
|
1
|
| 1 |
IC50 = 633.5 nM
|
|
|
|
CP0914658
|
1-(3-(Benzo[b]thiophen-3-yl)-3-(piperazin-1-yl)propyl)-4-benzyl-1,2,3,6-tetrahydropyridine
Show/Hide
|
C27H33N3S
|
1
|
| 1 |
IC50 = 635.4 nM
|
|
|
|
CP0389539
|
N,N-dimethyl-1-[2-(4-methylsulfanylphenyl)sulfanylphenyl]methanamine
Show/Hide
|
C16H19NS2
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0449716
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(1H-1,2,3-triazol-1-yl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C19H18Cl2N4
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0427475
|
2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-(3-nitrophenyl)-1,3-thiazole
Show/Hide
|
C23H22ClN3O2S
|
2
|
| 1 |
IC50 = 650 nM
|
|
|
| 2 |
Ki = 2510 nM
|
|
|
|
CP0444660
|
(1R,3S)-N-methyl-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C17H19NO
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0485871
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2-chlorophenyl)piperazine
Show/Hide
|
C27H29ClN6
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0430654
|
(R)-N-cyclopentyl-N-(pyrrolidin-3-yl)-2-naphthamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 = 677 nM
|
|
|
|
CP0456848
|
(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0398460
|
(2-(4-methoxyphenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C16H19NO2
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0054778
|
CAS_93413-69-5
Show/Hide
|
C17H27NO2
|
5
|
| 1 |
IC50 = 680 nM
|
|
|
| 2 |
IC50 = 5722 nM
|
|
|
| 3 |
IC50 = 7943.28 nM
|
|
|
| 4 |
Ki = 1623 nM
|
|
|
| 5 |
Ki > 553 nM
|
|
|
|
CP0372372
|
2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-(4-fluorophenyl)-1,3-thiazole
Show/Hide
|
C23H22ClFN2S
|
2
|
| 1 |
IC50 = 690 nM
|
|
|
| 2 |
Ki = 1700 nM
|
|
|
|
CP0291166
|
((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-2H-chromen-3-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0299582
|
2-(ethylaminomethyl)-1-(2-methylphenoxy)-1,3-dihydroinden-2-ol
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0437594
|
N-[3-[(dimethylamino)methyl]-4-[4-(trifluoromethyl)phenoxy]phenyl]methanesulfonamide
Show/Hide
|
C17H19F3N2O3S
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 = 770 nM
|
|
|
|
CP0422639
|
N,N-dimethyl-1-[(3R,4R)-4-(2-methylphenoxy)-3,4-dihydro-2H-chromen-3-yl]methanamine
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0450976
|
2-(ethylamino)-9- methyl-6-(4-(3- (methylamino)-1- phenylpropoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 716 nM
|
|
|
|
CP0005925
|
2-(N-Pyrrolidinyl)-3'-methoxypropiophenone
Show/Hide
|
C15H21NO2
|
1
|
| 1 |
IC50 = 718 nM
|
|
|
|
CP0428895
|
(R)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)acetamide
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
IC50 = 726 nM
|
|
|
|
CP0388387
|
(R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N-(pyrrolidin-3-yl)methanesulfonamide
Show/Hide
|
C17H21FN2O2S
|
1
|
| 1 |
IC50 = 735 nM
|
|
|
|
CP0004172
|
(2S,3S)-2-(3,4-Difluorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H17F2NO2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0427420
|
2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-phenyl-1,3-thiazole
Show/Hide
|
C23H23ClN2S
|
2
|
| 1 |
IC50 = 750 nM
|
|
|
| 2 |
Ki = 1840 nM
|
|
|
|
CP0449711
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(1H-1,2,4-triazol-1-yl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C19H18Cl2N4
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0398449
|
(2-(4-bromophenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C15H16BrNO
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0414873
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(2,4-dichlorophenyl)piperazine
Show/Hide
|
C25H33Cl2N3
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0449712
|
(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C17H18Cl2N2O2S
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0371084
|
(1R,2S)-2-((methylamino)methyl)-1-(o-tolyloxy)-2,3-dihydro-1H-inden-2-ol
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0384763
|
(R)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile
Show/Hide
|
C16H16N2O
|
1
|
| 1 |
IC50 = 772 nM
|
|
|
|
CP0394659
|
1-(3,4-dichlorophenyl)-2-piperidin-1-yl-pentan-1-one
Show/Hide
|
C16H21Cl2NO
|
2
|
| 1 |
IC50 = 800 nM
|
|
|
| 2 |
Ki = 2350 nM
|
|
|
|
CP0399293
|
(1R,3S)-N,N-dimethyl-3-phenoxy-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C17H19NO
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0559580
|
2-[4-[3-(5-benzhydryltetrazol-1-yl)propyl]piperazin-1-yl]pyrimidine
Show/Hide
|
C25H28N8
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0516871
|
1-methyl-4-[3-[3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-2,3-dihydro-1,4-benzodiazepin-5-one
Show/Hide
|
C24H27N3O2S
|
1
|
| 1 |
IC50 = 815 nM
|
|
|
|
CP0035683
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride
Show/Hide
|
C17H17Cl2N
|
1
|
| 1 |
IC50 = 825 nM
|
|
|
|
CP0384765
|
(+/-)-4-(2-methoxy-1-(naphthalen-2-yloxy)ethyl)piperidine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
IC50 = 827 nM
|
|
|
|
CP0002367
|
(2S,3S)-2-(4-Chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H18ClNO2
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0485063
|
(1S,3S)-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C16H17NO
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0460614
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(4-methylphenyl)piperazine
Show/Hide
|
C28H32N6
|
1
|
| 1 |
IC50 = 870 nM
|
|
|
|
CP0386601
|
(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid
Show/Hide
|
C18H17Cl2NO2
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0377419
|
N-methyl-1-[(1R,2S)-1-[4-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
|
C18H18F3NO
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0877358
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)-6-bromo-2-naphthamide
Show/Hide
|
C26H29BrN2O
|
1
|
| 1 |
IC50 = 885 nM
|
|
|
|
CP0381427
|
(+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-3-methylbutan-1-amine
Show/Hide
|
C17H25Cl2N
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0385630
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C26H37N3O
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0001189
|
2-(N-tert-Butylamino)-3'-chloro-4'-methylpropiophenone
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C14H20ClNO
|
3
|
| 1 |
IC50 = 900 nM
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| 2 |
IC50 = 2040 nM
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| 3 |
Ki = 5100 nM
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CP0193011
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N-methyl-1-[(3R,4R)-4-[2-(trifluoromethyl)phenoxy]-3,4-dihydro-1H-isochromen-3-yl]methanamine
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C18H18F3NO2
|
1
|
| 1 |
IC50 = 900 nM
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CP0486342
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5-(4-chlorophenyl)-2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
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C23H22Cl2N2S
|
2
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| 1 |
IC50 = 912 nM
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| 2 |
Ki = 2700 nM
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CP0442581
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2-((5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide
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C19H20Cl2N2O
|
1
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| 1 |
IC50 = 920 nM
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CP0460619
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1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-pyridin-2-ylpiperazine
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C26H29N7
|
1
|
| 1 |
IC50 = 920 nM
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CP0532505
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(1S,9S,10S)-4-(difluoromethyl)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
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C18H23F2N
|
2
|
| 1 |
IC50 = 944 nM
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| 2 |
Ki = 35 nM
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CP0485061
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(1R,4R)-4-(2-methylphenoxy)-1,2,3,4-tetrahydronaphthalen-1-amine
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C17H19NO
|
1
|
| 1 |
IC50 = 950 nM
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CP0728378
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cis-(+/-)-2-{5-[3-(5-fluoro-2-methoxyphenyl)-ethyl]-tetrahydro-furan-2-yl}-ethylamine)-pentyl]-4,5,8,8a-tetrahydro-2H-phthalazin-1-one
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C36H48FN3O5
|
2
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| 1 |
IC50 = 957 nM
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| 2 |
Ki = 1748 nM
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CP0442586
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N-[[(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]methyl]methanesulfonamide
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C19H22Cl2N2O2S
|
1
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| 1 |
IC50 = 960 nM
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CP0372377
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5-(4-bromophenyl)-2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
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C23H22BrClN2S
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2
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| 1 |
IC50 = 960 nM
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| 2 |
Ki = 3290 nM
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CP0381428
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(+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,3-dimethylbutan-1-amine
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C18H27Cl2N
|
1
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| 1 |
IC50 = 960 nM
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CP0449710
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((5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalen-2-yl)methanol
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C18H19Cl2NO
|
1
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| 1 |
IC50 = 980 nM
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CP0256332
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((3R,4R)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-3-yl)methanamine
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C17H19NO2
|
1
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| 1 |
IC50 = 1000 nM
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CP0398622
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N-methyl-1-[(3S,4R)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
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C18H21NO2
|
1
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| 1 |
IC50 = 1000 nM
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CP0414288
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6-(2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)quinoline
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C19H18N2
|
1
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| 1 |
IC50 = 1000 nM
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CP0035258
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N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
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C17H18F3NO
|
7
|
| 1 |
IC50 = 1020 nM
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| 2 |
IC50 = 2000 nM
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| 3 |
IC50 = 4410 nM
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| 4 |
IC50 = 5200 nM
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| 5 |
IC50 = 6309.57 nM
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| 6 |
Ki = 1394 nM
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| 7 |
Ki = 1560 nM
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CP0534927
|
(1S,9S,10S)-17-methyl-4-(trifluoromethyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Show/Hide
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C18H22F3N
|
2
|
| 1 |
IC50 = 1039 nM
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| 2 |
Ki > 10000 nM
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CP0431534
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4-(3,4-dichlorobenzyl)-3-((dimethylamino)methyl)benzenesulfonamide
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C16H18Cl2N2O2S
|
1
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| 1 |
IC50 = 1050 nM
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CP0556854
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1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(4-methoxyphenyl)piperazine
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C28H32N6O
|
1
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| 1 |
IC50 = 1060 nM
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CP0391150
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1-[3-(4-benzylpiperidin-1-yl)propyl]-4-(2,6-dimethylphenyl)piperazine
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C27H39N3
|
1
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| 1 |
IC50 = 1070 nM
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CP0430173
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1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-[2-fluoro-5-(trifluoromethyl)phenyl]piperazine
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C28H28F4N6
|
1
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| 1 |
IC50 = 1090 nM
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CP0432493
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(5S,8S)-8-(3,4-dichlorophenyl)-5-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
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|
C18H18Cl2N2O
|
1
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| 1 |
IC50 = 1100 nM
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CP0535159
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(1S,2R)-2-(aminomethyl)-N-(2-methoxyethyl)-N-methyl-1-thiophen-3-ylcyclopropane-1-carboxamide
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C13H20N2O2S
|
1
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| 1 |
IC50 = 1100 nM
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CP0440510
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(1R,3S)-N-methyl-3-(2-methylphenoxy)-N-propan-2-yl-2,3-dihydro-1H-inden-1-amine
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|
C20H25NO
|
1
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| 1 |
IC50 = 1100 nM
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CP0485857
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1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2,3-dichlorophenyl)piperazine
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C27H28Cl2N6
|
1
|
| 1 |
IC50 = 1100 nM
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CP0485858
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1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(4-chloro-2-fluorophenyl)piperazine
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|
C27H28ClFN6
|
1
|
| 1 |
IC50 = 1100 nM
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CP0002722
|
(2S,3S)-2-(m-Tolyl)-3,5,5-trimethylmorpholin-2-ol
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|
C14H21NO2
|
1
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| 1 |
IC50 = 1130 nM
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CP0439380
|
(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
IC50 = 1150 nM
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CP0372370
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5-(4-chlorophenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
|
C24H25ClN2S
|
2
|
| 1 |
IC50 = 1170 nM
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| 2 |
Ki = 2870 nM
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CP0385616
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-4-[4-(trifluoromethyl)phenyl]piperazine
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|
C26H34F3N3
|
1
|
| 1 |
IC50 = 1170 nM
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CP0000909
|
2-(N-Pyrrolidinyl)-3'-bromopropiophenone
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|
C14H18BrNO
|
1
|
| 1 |
IC50 = 1180 nM
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CP0384756
|
(R)-3-(naphthalen-2-ylmethoxy)pyrrolidine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
IC50 = 1200 nM
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CP0387987
|
N-(naphthalen-2-ylmethyl)-N-piperidin-4-ylpyrimidin-2-amine
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|
C20H22N4
|
1
|
| 1 |
IC50 = 1200 nM
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CP0388383
|
(R)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide
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|
C19H24N2O
|
1
|
| 1 |
IC50 = 1200 nM
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CP0390789
|
1-(2-methoxyphenyl)-4-(3-naphthalen-2-yloxypropyl)piperazine
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
IC50 = 1200 nM
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CP0485856
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(4-bromophenyl)piperazine
Show/Hide
|
C27H29BrN6
|
1
|
| 1 |
IC50 = 1200 nM
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CP0002369
|
(2S,3S)-2-(3-Nitrophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H18N2O4
|
1
|
| 1 |
IC50 = 1210 nM
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CP0386602
|
(5S,8S)-methyl 5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxylate
Show/Hide
|
C19H19Cl2NO2
|
1
|
| 1 |
IC50 = 1250 nM
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CP0419459
|
(5S,8S)-5-(3,4-dichlorophenyl)-N-methyl-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C18H20Cl2N2O2S
|
1
|
| 1 |
IC50 = 1250 nM
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CP0000908
|
1-(3-chlorophenyl)-2-(dimethylamino)propan-1-one
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|
C11H14ClNO
|
3
|
| 1 |
IC50 = 1260 nM
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|
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| 2 |
IC50 = 1520 nM
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| 3 |
Ki = 3090 nM
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CP0476510
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-chlorophenyl)piperazine
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|
C25H25ClF2N2O
|
1
|
| 1 |
IC50 = 1260 nM
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CP0455103
|
(2-(4-(methylthio)benzyl)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C17H21NS
|
1
|
| 1 |
IC50 = 1300 nM
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CP0468510
|
(2-(3,4-dichlorobenzyl)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C16H17Cl2N
|
1
|
| 1 |
IC50 = 1300 nM
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CP0452437
|
N-(naphthalen-2-ylmethyl)-N-piperidin-4-ylpropanamide
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 = 1300 nM
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CP0311653
|
N-methyl-1-[(3R,4R)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 1300 nM
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CP0476509
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-chlorophenyl)piperazine
Show/Hide
|
C25H25ClF2N2O
|
1
|
| 1 |
IC50 = 1313 nM
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CP0492093
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3,4-dichlorophenyl)piperazine
Show/Hide
|
C25H24Cl2F2N2O
|
1
|
| 1 |
IC50 = 1323 nM
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CP0392002
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
Show/Hide
|
C30H34N6
|
1
|
| 1 |
IC50 = 1327 nM
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CP0492698
|
N-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C22H24ClN3OS
|
1
|
| 1 |
IC50 = 1340 nM
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CP0495607
|
4-benzyl-1-[2-[5-(4-nitrophenyl)tetrazol-1-yl]ethyl]piperidine
Show/Hide
|
C21H24N6O2
|
1
|
| 1 |
IC50 = 1350 nM
|
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CP0384761
|
(+/-)-3-((naphthalen-2-yloxy)methyl)pyrrolidine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
IC50 = 1400 nM
|
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CP0474569
|
(2-(4-cyclopropylphenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 1400 nM
|
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CP0384767
|
4-(naphthalen-2-ylmethoxy)piperidine
Show/Hide
|
C16H19NO
|
2
|
| 1 |
IC50 = 1400 nM
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|
|
| 2 |
IC50 = 6500 nM
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CP0565255
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-phenylpiperazine
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|
C27H30N6
|
1
|
| 1 |
IC50 = 1450 nM
|
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CP0391891
|
3-(3,4-Dimethoxy-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Show/Hide
|
C18H25NO4
|
2
|
| 1 |
IC50 = 1452 nM
|
|
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| 2 |
Ki = 4500 nM
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CP0379349
|
3-(1-benzothiophen-2-yl)-N,N-dimethyl-3-morpholin-4-ylpropan-1-amine
Show/Hide
|
C17H24N2OS
|
1
|
| 1 |
IC50 = 1456.3 nM
|
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CP0682798
|
SID50106226
Show/Hide
|
C28H34Cl2F2N2O
|
1
|
| 1 |
IC50 = 1460 nM
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CP0411366
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-(3-phenylpropyl)piperazine
Show/Hide
|
C29H34N6
|
1
|
| 1 |
IC50 = 1467 nM
|
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CP0512161
|
(5S,8S)-5-(3,4-dichlorophenyl)-N-methyl-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Show/Hide
|
C19H20Cl2N2O
|
1
|
| 1 |
IC50 = 1500 nM
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CP0382158
|
(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C14H21N3O
|
1
|
| 1 |
IC50 = 1500 nM
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CP0530530
|
(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-pyridin-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C14H21N3O
|
1
|
| 1 |
IC50 = 1500 nM
|
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CP0377303
|
N-cyclobutyl-N-(naphthalen-2-ylmethyl)piperidin-4-amine
Show/Hide
|
C20H26N2
|
1
|
| 1 |
IC50 = 1500 nM
|
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CP0468514
|
(2-(4-ethoxyphenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C17H21NO2
|
1
|
| 1 |
IC50 = 1500 nM
|
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CP0013114
|
CAS_386750-22-7
Show/Hide
|
C16H25NO2
|
2
|
| 1 |
IC50 = 1500 nM
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| 2 |
Ki > 650 nM
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CP0411359
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-benzylpiperidine
Show/Hide
|
C30H35N5
|
1
|
| 1 |
IC50 = 1530 nM
|
|
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CP0573054
|
(6S)-13-(ethylamino)-8-[3-[3-(methylamino)-1-phenylpropoxy]phenyl]-2,8,12,14-tetrazatricyclo[8.4.0.02,6]tetradeca-1(14),10,12-trien-9-one
Show/Hide
|
C28H34N6O2
|
1
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| 1 |
IC50 = 1533 nM
|
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CP0494088
|
2-Aminomethyl-5-(pentafluorophenethyl)tetrahydrofuran
Show/Hide
|
C13H14F5NO
|
2
|
| 1 |
IC50 = 1541 nM
|
|
|
| 2 |
Ki = 634 nM
|
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CP0427472
|
2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-5-(4-nitrophenyl)-1,3-thiazole
Show/Hide
|
C24H25N3O2S
|
2
|
| 1 |
IC50 = 1550 nM
|
|
|
| 2 |
Ki = 1970 nM
|
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CP0000314
|
2-(N-Methyl-N-tert-butylamino)-3'-chloropropiophenone
Show/Hide
|
C14H20ClNO
|
2
|
| 1 |
IC50 = 1570 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
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CP0002368
|
(2S,3S)-2-(Naphthalen-2-yl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C23H25NO2
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
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CP0463703
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(4-chlorophenyl)piperazine
Show/Hide
|
C25H25ClF2N2O
|
1
|
| 1 |
IC50 = 1590 nM
|
|
|
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CP0444662
|
(1R,3S)-3-(4-chlorophenoxy)-N,N-dimethyl-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C17H18ClNO
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
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CP0460615
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(3-chlorophenyl)piperazine
Show/Hide
|
C27H29ClN6
|
1
|
| 1 |
IC50 = 1620 nM
|
|
|
|
CP0437111
|
2-[4-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperazin-1-yl]pyrimidine
Show/Hide
|
C23H24F2N4O
|
1
|
| 1 |
IC50 = 1621 nM
|
|
|
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CP0000013
|
1-(4-bromo-3-methylphenyl)-2-(tert-butylamino)propan-1-one
Show/Hide
|
C14H20BrNO
|
3
|
| 1 |
IC50 = 1623 nM
|
|
|
| 2 |
IC50 = 7250 nM
|
|
|
| 3 |
Ki = 4600 nM
|
|
|
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CP0000312
|
2-(N-tert-Butylamino)-3',4'-dichloropropiophenone
Show/Hide
|
C13H17Cl2NO
|
3
|
| 1 |
IC50 = 1670 nM
|
|
|
| 2 |
IC50 = 2100 nM
|
|
|
| 3 |
Ki = 5400 nM
|
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CP0000079
|
(2S,3S)-3,5,5-Trimethyl-2-(4-methylphenyl)morpholin-2-ol
Show/Hide
|
C14H21NO2
|
1
|
| 1 |
IC50 = 1680 nM
|
|
|
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CP0392007
|
N-[2-(4-benzylpiperidin-1-yl)ethyl]-2,2-diphenylacetamide
Show/Hide
|
C28H32N2O
|
1
|
| 1 |
IC50 = 1680 nM
|
|
|
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CP0476507
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-benzylpiperidine
Show/Hide
|
C28H31N5
|
1
|
| 1 |
IC50 = 1710 nM
|
|
|
|
CP0482667
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2,6-dimethylphenyl)piperazine
Show/Hide
|
C29H34N6
|
1
|
| 1 |
IC50 = 1720 nM
|
|
|
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CP0492097
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
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C29H32N6
|
1
|
| 1 |
IC50 = 1760 nM
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CP0417771
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2-[(2R,5R)-5-[(5-fluoro-2-methoxyphenyl)methyl]oxolan-2-yl]ethanamine
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C14H20FNO2
|
2
|
| 1 |
IC50 = 1774 nM
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| 2 |
Ki = 1782 nM
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CP0386605
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(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-6-(methylsulfinyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
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C18H19Cl2NOS
|
1
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| 1 |
IC50 = 1800 nM
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CP0485068
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4-((naphthalen-2-yloxy)methyl)piperidine
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C16H19NO
|
1
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| 1 |
IC50 = 1800 nM
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CP0372374
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5-(4-methoxyphenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
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C25H28N2OS
|
2
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| 1 |
IC50 = 1810 nM
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| 2 |
Ki = 3630 nM
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CP0372380
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5-(4-bromophenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
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C24H25BrN2S
|
2
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| 1 |
IC50 = 1820 nM
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| 2 |
Ki = 4240 nM
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CP0279261
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3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid (6-{[3-(4-chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carbonyl]-amino}-hexyl)-amide
Show/Hide
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C36H48Cl2N4O2
|
2
|
| 1 |
IC50 = 1846 nM
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| 2 |
Ki = 330 nM
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CP0546032
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6-(3-(3- (dimethylamino)-1- phenylpropoxy)phenyl)- 2-(ethylamino)-9- methyl-6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
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C27H34N6O2
|
1
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| 1 |
IC50 = 1862 nM
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CP0474508
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2-[(2R,5S)-5-[(5-fluoro-2-methoxyphenyl)methyl]oxolan-2-yl]ethanamine
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C14H20FNO2
|
2
|
| 1 |
IC50 = 1864 nM
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| 2 |
Ki = 455 nM
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CP0482669
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1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(3-fluorophenyl)piperazine
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C27H29FN6
|
1
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| 1 |
IC50 = 1890 nM
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CP0377306
|
6-(piperidin-4-ylmethoxy)-2-naphthonitrile
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C17H18N2O
|
1
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| 1 |
IC50 = 1900 nM
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CP0372822
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2-[5-[3-(5-fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]ethanamine
Show/Hide
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C16H24FNO2
|
2
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| 1 |
IC50 = 1930 nM
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| 2 |
Ki = 10600 nM
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CP0311788
|
(R)-Norfluoxetine
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C16H16F3NO
|
2
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| 1 |
IC50 = 1995 nM
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| 2 |
Ki = 7490 nM
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CP0010255
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(RS)-3,4-(methylenedioxy)methamphetamine
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C11H15NO2
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2
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| 1 |
IC50 = 1995.26 nM
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| 2 |
Ki = 398 nM
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CP0456845
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(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methylsulfinyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
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C18H19Cl2NOS
|
1
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| 1 |
IC50 = 2000 nM
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CP0468513
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N-[3-(methylaminomethyl)-4-(4-methylsulfanylphenyl)sulfanylphenyl]methanesulfonamide
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C16H20N2O2S3
|
1
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| 1 |
IC50 = 2000 nM
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CP0498000
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N,N-dimethyl-1-[2-[3-(trifluoromethyl)phenyl]sulfanylphenyl]methanamine
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C16H16F3NS
|
1
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| 1 |
IC50 = 2000 nM
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CP0373937
|
2-(N-tert-Butylamino)-3'-chloroheptanophenone
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C17H26ClNO
|
2
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| 1 |
IC50 = 2000 nM
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| 2 |
Ki = 4300 nM
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CP0399291
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(1R,3S)-N,N-diethyl-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
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|
C20H25NO
|
1
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| 1 |
IC50 = 2000 nM
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CP0490850
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(1R,3S)-N-methyl-3-phenoxy-2,3-dihydro-1H-inden-1-amine
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C16H17NO
|
1
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| 1 |
IC50 = 2000 nM
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CP0435001
|
N-[3-(4-benzylpiperidin-1-yl)propyl]-2,2-bis(4-chlorophenyl)acetamide
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C29H32Cl2N2O
|
1
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| 1 |
IC50 = 2020 nM
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CP0372369
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2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-5-(3-nitrophenyl)-1,3-thiazole
Show/Hide
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C24H25N3O2S
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2
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| 1 |
IC50 = 2040 nM
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| 2 |
Ki = 990 nM
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CP0060491
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10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
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C20H23N
|
2
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| 1 |
IC50 = 2041.74 nM
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| 2 |
Ki = 333 nM
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CP0528545
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2,4-dichlorophenyl)piperazine
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C27H28Cl2N6
|
1
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| 1 |
IC50 = 2050 nM
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CP0000443
|
2-(N-tert-Butylamino)-4'-chloropropiophenone
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C13H18ClNO
|
2
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| 1 |
IC50 = 2070 nM
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| 2 |
Ki > 10000 nM
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CP0308393
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(cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Show/Hide
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C38H43N3O4S
|
2
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| 1 |
IC50 = 2097 nM
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| 2 |
Ki = 3236 nM
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CP0441803
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(methylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C18H19Cl2NO2S
|
1
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| 1 |
IC50 = 2100 nM
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CP0449714
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(5S,8S)-8-(3,4-dichlorophenyl)-5-(methylamino)-3-(methylsulfonamido)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
Show/Hide
|
C19H21Cl2N3O3S
|
1
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| 1 |
IC50 = 2100 nM
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CP0464719
|
(5S,8S)-8-(3,4-dichlorophenyl)-5-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C17H18Cl2N2O2S
|
1
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| 1 |
IC50 = 2100 nM
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CP0409024
|
1-[2-(4-benzylpiperidin-1-yl)ethyl]-4-(4-bromophenyl)piperazine
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|
C24H32BrN3
|
1
|
| 1 |
IC50 = 2100 nM
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CP0377720
|
2-Aminoethyl-5-(4'-hydoxyphenethyl)tetrahydrofuran
Show/Hide
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C14H21NO2
|
2
|
| 1 |
IC50 = 2126 nM
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| 2 |
Ki = 5947 nM
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CP0415699
|
2-(N-Cyclopropylamino)-3-chloropropiophenone
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C12H14ClNO
|
2
|
| 1 |
IC50 = 2150 nM
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| 2 |
Ki = 4000 nM
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CP0460616
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(2,4-difluorophenyl)piperazine
Show/Hide
|
C27H28F2N6
|
1
|
| 1 |
IC50 = 2160 nM
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CP0277280
|
(cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Show/Hide
|
C38H43N3O4S
|
2
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| 1 |
IC50 = 2190 nM
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| 2 |
Ki > 100000 nM
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CP0437283
|
(1R,2R)-2-(aminomethyl)-1-(1,3-benzothiazol-2-yl)-N,N-diethylcyclopropane-1-carboxamide
Show/Hide
|
C16H21N3OS
|
1
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| 1 |
IC50 = 2200 nM
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CP0068314
|
N-[3-(4-benzylpiperidin-1-yl)propyl]-2,2-diphenylacetamide
Show/Hide
|
C29H34N2O
|
1
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| 1 |
IC50 = 2210 nM
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CP0189368
|
3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid (4-{[3-(4-chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carbonyl]-amino}-butyl)-amide
Show/Hide
|
C34H44Cl2N4O2
|
2
|
| 1 |
IC50 = 2258 nM
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| 2 |
Ki = 2068 nM
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CP0428783
|
4-benzyl-1-[3-[5-(4-fluorophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
|
C22H26FN5
|
1
|
| 1 |
IC50 = 2280 nM
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CP0427468
|
5-(3-bromophenyl)-2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
|
C23H22BrClN2S
|
2
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| 1 |
IC50 = 2300 nM
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| 2 |
Ki = 2530 nM
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CP0377717
|
2-Aminomethyl-5-(p-t-butylphenyl)tetrahydrofuran
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|
C15H23NO
|
2
|
| 1 |
IC50 = 2322 nM
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| 2 |
Ki = 4543 nM
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CP0000313
|
2-(N-tert-Butylamino)-4'-methylpropiophenone
Show/Hide
|
C14H21NO
|
3
|
| 1 |
IC50 = 2350 nM
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|
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| 2 |
IC50 = 4100 nM
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| 3 |
Ki = 6840 nM
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CP0000183
|
(+/-)2-(3,5-Dichlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C13H17Cl2NO2
|
1
|
| 1 |
IC50 = 2440 nM
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CP0543114
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-[3-(trifluoromethyl)phenyl]piperazine
Show/Hide
|
C28H29F3N6
|
1
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| 1 |
IC50 = 2480 nM
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CP0430655
|
N-(naphthalen-2-ylmethyl)-N-piperidin-4-ylmethanesulfonamide
Show/Hide
|
C17H22N2O2S
|
1
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| 1 |
IC50 = 2500 nM
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CP0391740
|
1-[2-(4-benzylpiperidin-1-yl)ethyl]-4-(2,4-dichlorophenyl)piperazine
Show/Hide
|
C24H31Cl2N3
|
1
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| 1 |
IC50 = 2500 nM
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CP0412786
|
4-benzyl-1-[3-(5-naphthalen-1-yltetrazol-1-yl)propyl]piperidine
Show/Hide
|
C26H29N5
|
1
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| 1 |
IC50 = 2510 nM
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CP0403191
|
2-butylamin-1-yl-1-(3,4-dichlorophenyl)pentan-1-one
Show/Hide
|
C15H21Cl2NO
|
2
|
| 1 |
IC50 = 2520 nM
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| 2 |
Ki = 4200 nM
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CP0001202
|
1-(3-chlorophenyl)-2-(piperidin-1-yl)propan-1-one
Show/Hide
|
C14H18ClNO
|
3
|
| 1 |
IC50 = 2520 nM
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|
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| 2 |
IC50 = 4798 nM
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| 3 |
Ki = 4760 nM
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CP0000150
|
2-(N-Cyclopentylamino)-3'-bromopropiophenone
Show/Hide
|
C14H18BrNO
|
1
|
| 1 |
IC50 = 2530 nM
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CP0000442
|
1-(4-bromophenyl)-2-(tert-butylamino)propan-1-one
Show/Hide
|
C13H18BrNO
|
2
|
| 1 |
IC50 = 2540 nM
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| 2 |
Ki > 10000 nM
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CP0457497
|
4-benzyl-1-(3-naphthalen-2-yloxypropyl)piperidine
Show/Hide
|
C25H29NO
|
1
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| 1 |
IC50 = 2540 nM
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CP0475929
|
3-(1-benzothiophen-3-yl)-N,N-dimethyl-3-morpholin-4-ylpropan-1-amine
Show/Hide
|
C17H24N2OS
|
1
|
| 1 |
IC50 = 2541.5 nM
|
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CP0850338
|
VENLAFAXINE HYDROCHLORIDE
Show/Hide
|
C17H28ClNO2
|
3
|
| 1 |
IC50 = 2550 nM
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|
|
| 2 |
IC50 = 2553 nM
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| 3 |
IC50 = 5720 nM
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CP0411736
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C23H24Cl2N4O
|
1
|
| 1 |
IC50 = 2550 nM
|
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CP0412787
|
4-benzyl-1-[3-[5-(4-chlorophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
|
C22H26ClN5
|
1
|
| 1 |
IC50 = 2580 nM
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CP0403945
|
N,N'-bis[2-[bis(4-fluorophenyl)methoxy]ethyl]-N,N'-dimethylethane-1,2-diamine
Show/Hide
|
C34H36F4N2O2
|
2
|
| 1 |
IC50 = 2600 nM
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| 2 |
Ki = 261 nM
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CP0384757
|
(R)-N-ethyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfonamide
Show/Hide
|
C16H20N2O2S
|
1
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| 1 |
IC50 = 2600 nM
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CP0464555
|
N-[3-[4-(4-methylphenyl)piperazin-1-yl]propyl]naphthalene-2-carboxamide
Show/Hide
|
C25H29N3O
|
1
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| 1 |
IC50 = 2690 nM
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CP0451641
|
(5S,8S)-5-(3,4-dichlorophenyl)-N,N-dimethyl-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
Show/Hide
|
C19H22Cl2N2O2S
|
1
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| 1 |
IC50 = 2700 nM
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CP0479434
|
(2-(4-(cyclopropylmethyl)phenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
IC50 = 2700 nM
|
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CP0138144
|
2-[(2-hydroxyethylamino)methyl]-1-(2-methylphenoxy)-1,3-dihydroinden-2-ol
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
IC50 = 2800 nM
|
|
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CP0230943
|
(S)-Norfluoxetine
Show/Hide
|
C16H16F3NO
|
2
|
| 1 |
IC50 = 2806 nM
|
|
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| 2 |
Ki = 6186 nM
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CP0546710
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-(2-phenylethyl)piperazine
Show/Hide
|
C28H32N6
|
1
|
| 1 |
IC50 = 2830 nM
|
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CP0000201
|
2-(N-Cyclopentylamino)-3'-fluoropropiophenone
Show/Hide
|
C14H18FNO
|
1
|
| 1 |
IC50 = 2850 nM
|
|
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CP0386633
|
1-(4-bromophenyl)-4-(3-naphthalen-2-yloxypropyl)piperazine
Show/Hide
|
C23H25BrN2O
|
1
|
| 1 |
IC50 = 2850 nM
|
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CP0417772
|
[(2R,5R)-5-[3-(5-fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]methanamine
Show/Hide
|
C15H22FNO2
|
2
|
| 1 |
IC50 = 2857 nM
|
|
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| 2 |
Ki = 20180 nM
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CP0494700
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-nitro-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
|
C17H16Cl2N2O2
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
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CP0415800
|
(S)-3-(naphthalen-2-ylmethoxy)pyrrolidine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
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CP0439742
|
3-((dimethylamino)methyl)-N-methyl-4-(4-(trifluoromethoxy)phenoxy)benzamide
Show/Hide
|
C18H19F3N2O3
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
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CP0372820
|
[(2R,5S)-5-[3-(5-fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]methanamine
Show/Hide
|
C15H22FNO2
|
2
|
| 1 |
IC50 = 2934 nM
|
|
|
| 2 |
Ki = 8541 nM
|
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CP0374159
|
(R)-N-methyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfonamide
Show/Hide
|
C15H18N2O2S
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0415769
|
(R)-N-methyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C16H20N2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0444645
|
3-((dimethylamino)methyl)-4-(3-(trifluoromethyl)phenylthio)benzenesulfonamide
Show/Hide
|
C16H17F3N2O2S2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0399292
|
(1R,3S)-3-(2-methoxyphenoxy)-N,N-dimethyl-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0503264
|
(1R,3S)-N-ethyl-3-(2-methylphenoxy)-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0002723
|
(2S,3S)-2-(3-Methoxyphenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C14H21NO3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0451710
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C25H24Cl2F2N2O
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0428784
|
1-[3-[1-[3-(4-benzylpiperidin-1-yl)propyl]tetrazol-5-yl]phenyl]ethanone
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0425231
|
4-benzyl-1-[3-(5-phenyltetrazol-1-yl)propyl]piperidine
Show/Hide
|
C22H27N5
|
1
|
| 1 |
IC50 = 3030 nM
|
|
|
|
CP0425230
|
1-[3-[1-[2-(4-benzylpiperidin-1-yl)ethyl]tetrazol-5-yl]phenyl]ethanone
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C23H27N5O
|
1
|
| 1 |
IC50 = 3080 nM
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CP0468515
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(+/-)-(3,4-dichlorophenyl)(2-((dimethylamino)methyl)phenyl)methanol
Show/Hide
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C16H17Cl2NO
|
1
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| 1 |
IC50 = 3100 nM
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CP0489730
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((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-2H-chromen-3-yl)methanamine
Show/Hide
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C17H19NO2
|
1
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| 1 |
IC50 = 3100 nM
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CP0387890
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2-[(2R,5R)-5-[2-(5-fluoro-2-methoxyphenyl)ethyl]oxolan-2-yl]ethanamine
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C15H22FNO2
|
2
|
| 1 |
IC50 = 3101 nM
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| 2 |
Ki = 12100 nM
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CP0487617
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-4-phenylbenzamide
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C26H27Cl2N3O
|
1
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| 1 |
IC50 = 3150 nM
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CP0228182
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(+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine
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C10H13NO2
|
2
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| 1 |
IC50 = 3162.28 nM
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| 2 |
Ki = 704 nM
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CP0386599
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(5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carbonitrile
Show/Hide
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C18H16Cl2N2
|
1
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| 1 |
IC50 = 3200 nM
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CP0471341
|
1-(1-(4-(trifluoromethoxy)phenyl)cyclohexyl)ethanamine
Show/Hide
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C15H20F3NO
|
1
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| 1 |
IC50 = 3200 nM
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CP0427473
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5-(3-bromophenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
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C24H25BrN2S
|
2
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| 1 |
IC50 = 3240 nM
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| 2 |
Ki = 2210 nM
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CP0387889
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[(2R,5S)-5-[(5-fluoro-2-methoxyphenyl)methyl]oxolan-2-yl]methanamine
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C13H18FNO2
|
2
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| 1 |
IC50 = 3392 nM
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| 2 |
Ki = 9085 nM
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CP0495947
|
2-(Aminomethyl)-5-(1'-naphthethyl)tetrahydrofuran
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C17H21NO
|
2
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| 1 |
IC50 = 3420 nM
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| 2 |
Ki > 10000 nM
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CP0425234
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4-benzyl-1-[3-[5-(2,3-dichlorophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
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C22H25Cl2N5
|
1
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| 1 |
IC50 = 3450 nM
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CP0412785
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4-benzyl-1-[3-[5-(2-bromophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
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C22H26BrN5
|
1
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| 1 |
IC50 = 3460 nM
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CP0425233
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4-benzyl-1-[3-[5-(3-chlorophenyl)tetrazol-1-yl]propyl]piperidine
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C22H26ClN5
|
1
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| 1 |
IC50 = 3590 nM
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CP0389955
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-benzothiophene-2-carboxamide
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C22H23Cl2N3OS
|
1
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| 1 |
IC50 = 3660 nM
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CP0440579
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(1S,2R)-N,N-diethyl-2-(methylaminomethyl)-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
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C14H22N2OS
|
1
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| 1 |
IC50 = 3700 nM
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CP0375955
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5-[(1R,2R)-2-(methylaminomethyl)cyclopentyl]-1H-indole-3-carbonitrile
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C16H19N3
|
1
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| 1 |
IC50 = 3700 nM
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CP0390738
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1-(4-fluorophenyl)-4-(4-naphthalen-2-yloxybutyl)piperazine
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C24H27FN2O
|
1
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| 1 |
IC50 = 3710 nM
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CP0002070
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1-(1H-Indol-3-yl)-2-propanamine
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C11H14N2
|
3
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| 1 |
IC50 = 3715.35 nM
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| 2 |
Ki = 642 nM
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| 3 |
Ki > 10000 nM
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CP0437112
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1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2,4-dichlorophenyl)piperazine
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C25H24Cl2F2N2O
|
1
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| 1 |
IC50 = 3750 nM
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CP0000057
|
(2S,3S)-2-(4-Fluorophenyl)-3,5,5-trimethylmorpholin-2-ol
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C13H18FNO2
|
1
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| 1 |
IC50 = 3800 nM
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CP0478095
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4-benzyl-1-[3-[5-(2-chlorophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
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C22H26ClN5
|
1
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| 1 |
IC50 = 3960 nM
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CP0427470
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5-(3,4-dichlorophenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
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C24H24Cl2N2S
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2
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| 1 |
IC50 = 4000 nM
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| 2 |
Ki > 6100 nM
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CP0444663
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(1R,3S)-3-(4-chlorophenoxy)-N-methyl-2,3-dihydro-1H-inden-1-amine
Show/Hide
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C16H16ClNO
|
1
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| 1 |
IC50 = 4000 nM
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CP0501894
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(1R,3S)-3-(4-chlorophenoxy)-2,3-dihydro-1H-inden-1-amine
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C15H14ClNO
|
1
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| 1 |
IC50 = 4000 nM
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CP0377979
|
1-(1-(naphthalen-1-yl)cyclohexyl)ethanamine
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C18H23N
|
1
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| 1 |
IC50 = 4000 nM
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CP0395777
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1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine
Show/Hide
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C20H25N
|
1
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| 1 |
IC50 = 4000 nM
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CP0531990
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-(3,4-dichlorophenyl)piperazine
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C27H28Cl2N6
|
1
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| 1 |
IC50 = 4000 nM
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CP0001190
|
2-(N-Pyrrolidinyl)-3'-nitropropiophenone
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C14H18N2O3
|
1
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| 1 |
IC50 = 4100 nM
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CP0449715
|
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-6-(methylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
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C18H19Cl2NO2S
|
1
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| 1 |
IC50 = 4200 nM
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CP0479562
|
3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)phenoxy)benzamide
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|
C17H17F3N2O3
|
1
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| 1 |
IC50 = 4200 nM
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CP0427474
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2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-(3,4-dimethoxyphenyl)-1,3-thiazole
Show/Hide
|
C25H27ClN2O2S
|
2
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| 1 |
IC50 = 4210 nM
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| 2 |
Ki = 1910 nM
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CP0476505
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1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-benzylpiperazine
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C27H30N6
|
1
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| 1 |
IC50 = 4218 nM
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CP0412790
|
4-benzyl-1-[3-[5-(3-bromophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
|
C22H26BrN5
|
1
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| 1 |
IC50 = 4340 nM
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CP0399682
|
7-(piperidin-4-ylmethoxy)-2-naphthonitrile
Show/Hide
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C17H18N2O
|
1
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| 1 |
IC50 = 4400 nM
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CP0689683
|
SID50106352
Show/Hide
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C17H19ClF3NO
|
1
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| 1 |
IC50 = 4410 nM
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CP0377434
|
N,N-dimethyl-1-[(1R,2S)-1-[4-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
|
C19H20F3NO
|
1
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| 1 |
IC50 = 4500 nM
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CP0430987
|
2-(N,N-Diethylamino)-3'-chloropropiophenone
Show/Hide
|
C13H18ClNO
|
2
|
| 1 |
IC50 = 4603 nM
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| 2 |
Ki = 4476 nM
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CP0543113
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-pyridin-2-ylpiperazine
Show/Hide
|
C27H31N7
|
1
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| 1 |
IC50 = 4700 nM
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CP0377723
|
[(2R,5R)-5-[2-(5-fluoro-2-methoxyphenyl)ethyl]oxolan-2-yl]methanamine
Show/Hide
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C14H20FNO2
|
2
|
| 1 |
IC50 = 4746 nM
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| 2 |
Ki = 8520 nM
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CP0903378
|
N-(3-(4-Benzylpiperidin-1-yl)propyl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C24H28N2OS
|
1
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| 1 |
IC50 = 4750 nM
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CP0396974
|
3-[(4-ethylphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C19H24N2O
|
1
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| 1 |
IC50 = 4850 nM
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CP0372379
|
5-(4-fluorophenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
|
C24H25FN2S
|
2
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| 1 |
IC50 = 4870 nM
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| 2 |
Ki = 1630 nM
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CP0373936
|
2-(N-tert-Butylamino)-3'-chlorooctanophenone
Show/Hide
|
C18H28ClNO
|
2
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| 1 |
IC50 = 4890 nM
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| 2 |
Ki = 2580 nM
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CP0418052
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(5-chloro-2-(4-(methylthio)phenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C16H18ClNOS
|
1
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| 1 |
IC50 = 4900 nM
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CP0389954
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-phenylbenzamide
Show/Hide
|
C27H31N3O2
|
1
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| 1 |
IC50 = 4960 nM
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CP0386604
|
(5S,8S)-8-(3,4-dichlorophenyl)-N-methyl-5-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
Show/Hide
|
C19H20Cl2N2O
|
1
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| 1 |
IC50 = 5000 nM
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CP0422645
|
N,N-dimethyl-1-[(1R,2S)-1-(2-methylphenoxy)-2,3-dihydro-1H-inden-2-yl]methanamine
Show/Hide
|
C19H23NO
|
1
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| 1 |
IC50 = 5000 nM
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CP0456135
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(1R,3S)-3-phenoxy-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C15H15NO
|
1
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| 1 |
IC50 = 5000 nM
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CP0378738
|
1-(1-(4-tert-butoxyphenyl)cyclohexyl)ethanamine
Show/Hide
|
C18H29NO
|
1
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| 1 |
IC50 = 5000 nM
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CP0425235
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4-benzyl-1-[3-[5-(4-nitrophenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
|
C22H26N6O2
|
1
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| 1 |
IC50 = 5020 nM
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CP0428787
|
4-benzyl-1-[3-[5-[3-(trifluoromethyl)phenyl]tetrazol-1-yl]propyl]piperidine
Show/Hide
|
C23H26F3N5
|
1
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| 1 |
IC50 = 5100 nM
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CP0457498
|
1-(4-fluorophenyl)-4-(2-naphthalen-2-yloxyethyl)piperazine
Show/Hide
|
C22H23FN2O
|
1
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| 1 |
IC50 = 5130 nM
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CP0448761
|
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-phenylpiperazine
Show/Hide
|
C25H26F2N2O
|
1
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| 1 |
IC50 = 5328 nM
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CP0415771
|
(S)-N-methyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-amine
Show/Hide
|
C16H20N2
|
1
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| 1 |
IC50 = 5400 nM
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CP0412784
|
4-benzyl-1-[3-[5-(4-methoxyphenyl)tetrazol-1-yl]propyl]piperidine
Show/Hide
|
C23H29N5O
|
1
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| 1 |
IC50 = 5520 nM
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CP0415768
|
(S)-N-butyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfonamide
Show/Hide
|
C18H24N2O2S
|
1
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| 1 |
IC50 = 5600 nM
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CP0433911
|
N-[[3-[(dimethylamino)methyl]-4-[4-(trifluoromethoxy)phenoxy]phenyl]methyl]methanesulfonamide
Show/Hide
|
C18H21F3N2O4S
|
1
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| 1 |
IC50 = 5600 nM
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CP0000316
|
1-(3-bromophenyl)-2-(tert-butylamino)propan-1-one
Show/Hide
|
C13H18BrNO
|
3
|
| 1 |
IC50 = 5600 nM
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| 2 |
IC50 = 6500 nM
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| 3 |
Ki > 7140 nM
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CP0388333
|
(R)-3,4-dichloro-N-isopropyl-2-methyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H20Cl2N2O
|
1
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| 1 |
IC50 = 5700 nM
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CP0386634
|
1-(3-chlorophenyl)-4-(2-naphthalen-2-yloxyethyl)piperazine
Show/Hide
|
C22H23ClN2O
|
1
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| 1 |
IC50 = 5830 nM
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CP0387619
|
3-[(4-methylsulfanylphenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C18H22N2OS
|
1
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| 1 |
IC50 = 5850 nM
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CP0068316
|
4-benzyl-1-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperidine
Show/Hide
|
C27H29F2NO
|
1
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| 1 |
IC50 = 5862 nM
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CP0444646
|
N-methyl-1-[2-[4-(trifluoromethyl)phenyl]sulfanylphenyl]methanamine
Show/Hide
|
C15H14F3NS
|
1
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| 1 |
IC50 = 6000 nM
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CP0430656
|
(R)-N-cyclobutyl-N-(pyrrolidin-3-yl)-2-naphthamide
Show/Hide
|
C19H22N2O
|
1
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| 1 |
IC50 = 6000 nM
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CP0456137
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(1R,3S)-3-(4-methoxyphenoxy)-N,N-dimethyl-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C18H21NO2
|
1
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| 1 |
IC50 = 6000 nM
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CP0514500
|
N-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C24H28N4O2
|
1
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| 1 |
IC50 = 6070 nM
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CP0000014
|
2-(N-tert-Butylamino)-3'-methylpropiophenone
Show/Hide
|
C14H21NO
|
2
|
| 1 |
IC50 = 6200 nM
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| 2 |
Ki > 10000 nM
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CP0372831
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N-[3-[(dimethylamino)methyl]-4-[4-(trifluoromethyl)phenyl]sulfanylphenyl]methanesulfonamide
Show/Hide
|
C17H19F3N2O2S2
|
1
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| 1 |
IC50 = 6400 nM
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CP0000445
|
2-(tert-butylamino)-1-(3,4-difluorophenyl)propan-1-one
Show/Hide
|
C13H17F2NO
|
2
|
| 1 |
IC50 = 6480 nM
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| 2 |
Ki > 10000 nM
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CP0372371
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2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-(3,4-dichlorophenyl)-1,3-thiazole
Show/Hide
|
C23H21Cl3N2S
|
2
|
| 1 |
IC50 = 6500 nM
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| 2 |
Ki = 2300 nM
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CP0000441
|
2-(tert-Butylamino)-3'-fluoropropiophenone
Show/Hide
|
C13H18FNO
|
2
|
| 1 |
IC50 = 6500 nM
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|
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| 2 |
Ki > 10000 nM
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CP0194133
|
4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Show/Hide
|
C37H42F3N3O4
|
2
|
| 1 |
IC50 = 6553 nM
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| 2 |
Ki = 4600 nM
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CP0389538
|
N,N-dimethyl-1-[2-[4-(trifluoromethoxy)phenoxy]phenyl]methanamine
Show/Hide
|
C16H16F3NO2
|
1
|
| 1 |
IC50 = 6700 nM
|
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CP0440772
|
(S)-6-((pyrrolidin-3-yloxy)methyl)-2-naphthonitrile
Show/Hide
|
C16H16N2O
|
1
|
| 1 |
IC50 = 6800 nM
|
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CP0270322
|
4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Show/Hide
|
C37H42F3N3O4
|
2
|
| 1 |
IC50 = 6811 nM
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|
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| 2 |
Ki = 6567 nM
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CP0443612
|
(R)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)methanesulfonamide
Show/Hide
|
C16H20N2O2S
|
1
|
| 1 |
IC50 = 7000 nM
|
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CP0474700
|
[(2R,5S)-5-[4-(5-fluoro-2-methoxyphenyl)butyl]oxolan-2-yl]methanamine
Show/Hide
|
C16H24FNO2
|
2
|
| 1 |
IC50 = 7124 nM
|
|
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| 2 |
Ki = 2222 nM
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CP0504324
|
(2-(4-(methylthio)benzyl)phenyl)-N-methylmethanamine
Show/Hide
|
C16H19NS
|
1
|
| 1 |
IC50 = 7300 nM
|
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CP0728379
|
Cis-(+/-)-2-{5-[3-(5-Fluoro-2-methoxy-phenyl)-propyl]-tetrahydro-furan-2-yl}-ethylamine)-pentyl-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one
Show/Hide
|
C37H50FN3O5
|
2
|
| 1 |
IC50 = 7441 nM
|
|
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| 2 |
Ki = 7441 nM
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CP0439200
|
(R)-N-isopropyl-N-(pyrrolidin-3-yl)-2-naphthamide
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
IC50 = 7500 nM
|
|
|
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CP0354231
|
(+/-)-trans-3-(2-((dimethylamino)methyl)cyclopentyl)-1H-indole-5-carbonitrile
Show/Hide
|
C17H21N3
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
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CP0372384
|
(5-bromo-2-(4-(methylthio)phenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C16H18BrNOS
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0001472
|
(+/-)3,5,5-Trimethyl-2-(pyridin-2-yl)morpholin-2-ol
Show/Hide
|
C12H18N2O2
|
1
|
| 1 |
IC50 = 7950 nM
|
|
|
|
CP0502147
|
[(2R,5R)-5-[(5-fluoro-2-methoxyphenyl)methyl]oxolan-2-yl]methanamine
Show/Hide
|
C13H18FNO2
|
2
|
| 1 |
IC50 = 7983 nM
|
|
|
| 2 |
Ki = 24120 nM
|
|
|
|
CP0440599
|
((3R,4R)-1,1-Dioxo-4-o-tolyloxy-1lambda*6*-thiochroman-3-ylmethyl)-methyl-amine
Show/Hide
|
C18H21NO3S
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0384799
|
N-[2-(4-benzylpiperidin-1-yl)ethyl]-2,2-bis(4-chlorophenyl)acetamide
Show/Hide
|
C28H30Cl2N2O
|
1
|
| 1 |
IC50 = 8030 nM
|
|
|
|
CP0000011
|
2-(N-Cyclopentylamino)-3'-methoxypropiophenone
Show/Hide
|
C15H21NO2
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0482410
|
5-[(1R,2R)-2-[(dimethylamino)methyl]cyclopentyl]-1H-indole-3-carbonitrile
Show/Hide
|
C17H21N3
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0384766
|
1-(2-(6-fluoro-1-methylnaphthalen-2-yl)ethyl)piperazine
Show/Hide
|
C17H21FN2
|
1
|
| 1 |
IC50 = 8400 nM
|
|
|
|
CP0372823
|
2-Aminoethyl-5-(3'-(2''-methoxy-5''-fluorophenyl)-1'-butyl)tetrahydrofuran
Show/Hide
|
C17H26FNO2
|
2
|
| 1 |
IC50 = 8530 nM
|
|
|
| 2 |
Ki = 4064 nM
|
|
|
|
CP0485854
|
2-[4-[4-(5-benzhydryltetrazol-1-yl)butyl]piperazin-1-yl]pyrimidine
Show/Hide
|
C26H30N8
|
1
|
| 1 |
IC50 = 8540 nM
|
|
|
|
CP0522407
|
(3,4-dichlorophenyl)(2-((dimethylamino)methyl)phenyl)methanone
Show/Hide
|
C16H15Cl2NO
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0455291
|
2-(N-tert-Butylamino)propiophenone
Show/Hide
|
C13H19NO
|
2
|
| 1 |
IC50 = 8700 nM
|
|
|
| 2 |
Ki = 5700 nM
|
|
|
|
CP0001201
|
2-(N-Cyclopentylamino)-3'-methylpropiophenone
Show/Hide
|
C15H21NO
|
1
|
| 1 |
IC50 = 8700 nM
|
|
|
|
CP0460613
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C28H30Cl2N6
|
1
|
| 1 |
IC50 = 8870 nM
|
|
|
|
CP0439201
|
N-(naphthalen-2-ylmethyl)-N-piperidin-4-ylacetamide
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
|
CP0399799
|
10-(5-(diethylamino)pentyl)acridin-9(10H)-one
Show/Hide
|
C22H28N2O
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0441801
|
(5S,8S)-8-(3,4-dichlorophenyl)-5-(methylamino)-3-(methylsulfonamido)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
Show/Hide
|
C19H20Cl2N2O4S
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0171392
|
(+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-indole-5-carbonitrile
Show/Hide
|
C15H17N3
|
1
|
| 1 |
IC50 = 9200 nM
|
|
|
|
CP0522175
|
N,N-dimethyl-1-[2-[4-(trifluoromethyl)phenyl]sulfanylphenyl]methanamine
Show/Hide
|
C16H16F3NS
|
1
|
| 1 |
IC50 = 9200 nM
|
|
|
|
CP0442582
|
2-((5S,8S)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalen-2-yl)acetic acid
Show/Hide
|
C19H19Cl2NO2
|
1
|
| 1 |
IC50 = 9600 nM
|
|
|
|
CP0386632
|
1-(2,4-dichlorophenyl)-4-(4-naphthalen-2-yloxybutyl)piperazine
Show/Hide
|
C24H26Cl2N2O
|
1
|
| 1 |
IC50 = 9740 nM
|
|
|
|
CP0375006
|
10-(3-(diethylamino)propyl)acridin-9(10H)-one
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0399798
|
10-(4-(diethylamino)butyl)acridin-9(10H)-one
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0399800
|
10-(6-(diethylamino)hexyl)acridin-9(10H)-one
Show/Hide
|
C23H30N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0490662
|
10-(2-(diethylamino)ethyl)acridin-9(10H)-one
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0382254
|
(1S,2R)-2-[(dimethylamino)methyl]-N,N-diethyl-1-thiophen-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C15H24N2OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401362
|
3-((dimethylamino)methyl)-4-(3-methyl-4-(methylsulfinyl)phenoxy)benzenesulfonamide
Show/Hide
|
C17H22N2O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0476371
|
3-((dimethylamino)methyl)-4-(4-(methylsulfinyl)phenoxy)benzenesulfonamide
Show/Hide
|
C16H20N2O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0235553
|
((1S,2R)-2-methoxy-1-(o-tolyloxy)-2,3-dihydro-1H-inden-2-yl)-N-methylmethanamine
Show/Hide
|
C19H23NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0372830
|
2-(Aminomethyl)-5-(3'-pyridinylethyl)tetrahydrofuran
Show/Hide
|
C12H18N2O
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 8517 nM
|
|
|
|
CP0387888
|
2-[(2R,5S)-5-(5-fluoro-2-methoxyphenyl)oxolan-2-yl]ethanamine
Show/Hide
|
C13H18FNO2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 48870 nM
|
|
|
|
CP0417770
|
2-[(2R,5R)-5-(5-fluoro-2-methoxyphenyl)oxolan-2-yl]ethanamine
Show/Hide
|
C13H18FNO2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 27500 nM
|
|
|
|
CP0417776
|
2-(2'-Aminoethyl)-5-(2''-furyl)tetrahydrofuran
Show/Hide
|
C10H15NO2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0474507
|
2-Aminomethyl-5-(2'-methoxy-5'-fluorophenyl)tetrahydrofuran
Show/Hide
|
C12H16FNO2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 57020 nM
|
|
|
|
CP0481729
|
[(2R,5R)-5-(5-fluoro-2-methoxyphenyl)oxolan-2-yl]methanamine
Show/Hide
|
C12H16FNO2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 71990 nM
|
|
|
|
CP0440773
|
N-ethyl-N-piperidin-4-ylnaphthalene-2-sulfonamide
Show/Hide
|
C17H22N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0398450
|
(5-bromo-2-(4-(trifluoromethyl)phenoxy)phenyl)-N,N-dimethylmethanamine
Show/Hide
|
C16H15BrF3NO
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485028
|
3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)phenoxy)benzenesulfonamide
Show/Hide
|
C16H17F3N2O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0490842
|
3-((dimethylamino)methyl)-4-(4-(trifluoromethyl)phenylthio)benzenesulfonamide
Show/Hide
|
C16H17F3N2O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0502113
|
(+/-)-3-((dimethylamino)methyl)-4-(4-(trifluoromethyl)phenylsulfinyl)benzenesulfonamide
Show/Hide
|
C16H17F3N2O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0373896
|
2-(N-tert-Butylamino)-3'-chlorophenyl-4-cyclohexylbutanophenone
Show/Hide
|
C20H30ClNO
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 3800 nM
|
|
|
|
CP0427016
|
(+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethyl)-1H-indole-5-carbonitrile
Show/Hide
|
C21H21N3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0378736
|
1-(1-(thiophen-2-yl)cyclohexyl)ethanamine
Show/Hide
|
C12H19NS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0454408
|
(+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N,3-trimethylbutan-1-amine
Show/Hide
|
C19H29Cl2N
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412792
|
4-benzyl-1-[2-(5-naphthalen-1-yltetrazol-1-yl)ethyl]piperidine
Show/Hide
|
C25H27N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389952
|
N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]naphthalene-2-carboxamide
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389953
|
N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]naphthalene-1-carboxamide
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389956
|
N-[3-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C23H24F3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389957
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389958
|
N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]naphthalene-2-carboxamide
Show/Hide
|
C23H26N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389959
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]naphthalene-1-carboxamide
Show/Hide
|
C24H25Cl2N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0423657
|
N-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]naphthalene-2-carboxamide
Show/Hide
|
C24H26ClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0438688
|
N-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C23H24Cl2N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0445911
|
N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]quinoline-2-carboxamide
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0462124
|
N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]naphthalene-1-carboxamide
Show/Hide
|
C23H26N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0469702
|
3,5-dichloro-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
|
C20H21Cl4N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471847
|
N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]quinoline-2-carboxamide
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471962
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C22H23Cl2N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0481895
|
N-[3-[4-(2,4-dichlorophenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C23H24Cl2N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0481896
|
N-[3-[4-(4-methylphenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C24H28N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0486459
|
3,5-dichloro-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C19H22Cl2N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0487133
|
3,5-dichloro-N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C18H21Cl2N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0513477
|
N-[3-(4-phenylpiperazin-1-yl)propyl]quinoline-2-carboxamide
Show/Hide
|
C23H26N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0548241
|
N-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]quinoline-2-carboxamide
Show/Hide
|
C23H25ClN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0430172
|
2-[4-[2-(5-benzhydryltetrazol-1-yl)ethyl]piperazin-1-yl]pyrimidine
Show/Hide
|
C24H26N8
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0460618
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-(4-chlorophenyl)piperazine
Show/Hide
|
C26H27ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0482668
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-pyridin-2-ylpiperazine
Show/Hide
|
C25H27N7
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485855
|
1-[3-(5-benzhydryltetrazol-1-yl)propyl]-4-[4-(trifluoromethyl)phenyl]piperazine
Show/Hide
|
C28H29F3N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485869
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C29H34N6O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0538179
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C26H26Cl2N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0540784
|
1-[4-(5-benzhydryltetrazol-1-yl)butyl]-4-(4-chlorophenyl)piperazine
Show/Hide
|
C28H31ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0560220
|
1-[2-(5-benzhydryltetrazol-1-yl)ethyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C27H30N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0189277
|
2-(ethylamino)-9- methyl-6-(3-(5-methyl- 1,3,4-oxadiazol-2- yl)phenyl)-6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C19H21N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0294916
|
(S)-3-(aminomethyl)-5-methylhexanoic acid
Show/Hide
|
C8H17NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450977
|
(6R)-13-(ethylamino)-8-[3-[3-(methylamino)-1-phenylpropoxy]phenyl]-2,8,12,14-tetrazatricyclo[8.4.0.02,6]tetradeca-1(14),10,12-trien-9-one
Show/Hide
|
C28H34N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0560471
|
2-[ethyl(methyl)amino]-9-methyl-6-[3-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]-7,8-dihydropyrimido[4,5-e][1,4]diazepin-5-one
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0560472
|
9-methyl-6-(3-(5- methyl-1,3,4- oxadiazol-2-yl)phenyl)- 2-(methylamino)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C18H19N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0570860
|
2-(ethylamino)-N-methyl-N-[3-[3-(methylamino)-1-phenylpropoxy]phenyl]pyrimidine-5-carboxamide
Show/Hide
|
C24H29N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0571507
|
2-((2- methoxyethyl)amino)- 9-methyl-6-(3-(5- methyl-1,3,4- oxadiazol-2-yl)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C20H23N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0573053
|
2-(ethylamino)-9- methyl-6-(2-(3- (methylamino)-1- phenylpropoxy)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0575276
|
N-ethyl-9-methyl-6-(3- (5-methyl-1,3,4- oxadiazol-2-yl)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-2- amine
Show/Hide
|
C19H23N7O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0575278
|
2-(ethylamino)-9- methyl-6-(2-((3- (methylamino)-1- phenylpropoxy)methyl) phenyl)-6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C27H34N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0576437
|
9-methyl-6-(3-(5- methyl-1,3,4- oxadiazol-2- yl)phenyl)- 2-(methylthio)- 6,7,8,9- tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin- 5-one
Show/Hide
|
C18H18N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0577682
|
(6S)-13-(ethylamino)-8-[3-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-2,8,12,14-tetrazatricyclo[8.4.0.02,6]tetradeca-1(14),10,12-trien-9-one
Show/Hide
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C21H23N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
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CP0578637
|
9-ethyl-2-(ethylamino)- 6-(3-(5-methyl-1,3,4- oxadiazol-2-yl)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0546133
|
(1S,9S,10S)-4-(difluoromethoxy)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Show/Hide
|
C18H23F2NO
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki > 10000 nM
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CP0564571
|
Dextromethorphan
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|
C18H25NO
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki > 10000 nM
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CP0568482
|
(1S,9S,10S)-17-methyl-4-(trifluoromethoxy)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Show/Hide
|
C18H22F3NO
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki > 10000 nM
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CP0000177
|
(2S,3S)-2-Biphenyl-4-yl-3,5,5-trimethylmorpholin-2-ol
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|
C19H23NO2
|
1
|
| 1 |
IC50 = 10300 nM
|
|
|
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CP0377307
|
1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine
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|
C16H19FN2
|
1
|
| 1 |
IC50 = 10500 nM
|
|
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CP0374157
|
(R)-3-((6-fluoronaphthalen-2-yl)methoxy)pyrrolidine
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|
C15H16FNO
|
1
|
| 1 |
IC50 = 10600 nM
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|
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CP0442584
|
(5S,8S)-8-(3,4-dichlorophenyl)-N,N-dimethyl-5-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
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|
C20H22Cl2N2O
|
1
|
| 1 |
IC50 = 11500 nM
|
|
|
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CP0418570
|
3-((dimethylamino)methyl)-N-methyl-4-(4-(methylsulfinyl)phenoxy)benzenesulfonamide
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|
C17H22N2O4S2
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0000012
|
2-(tert-Butylamino)-3',5'-dichloropropiophenone
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|
C13H17Cl2NO
|
2
|
| 1 |
IC50 = 14000 nM
|
|
|
| 2 |
Ki > 10000 nM
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CP0443614
|
(R)-3,4-dichloro-N-ethyl-2-methyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C14H18Cl2N2O
|
1
|
| 1 |
IC50 = 17400 nM
|
|
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CP0441802
|
(5S,8S)-8-(3,4-dichlorophenyl)-5-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
Show/Hide
|
C18H17Cl2NO2
|
1
|
| 1 |
IC50 = 20300 nM
|
|
|
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CP0453792
|
tetrahydrofuranyl ethylamine, 24
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|
C16H24FNO2
|
2
|
| 1 |
IC50 = 20370 nM
|
|
|
| 2 |
Ki = 19332 nM
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CP0445577
|
1-(4-naphthalen-2-yloxybutyl)-4-[4-(trifluoromethyl)phenyl]piperazine
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|
C25H27F3N2O
|
1
|
| 1 |
IC50 = 20500 nM
|
|
|
|
CP0475247
|
5-[[(R)-[(R)-(4-bromophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14BrNOS2
|
1
|
| 1 |
IC50 = 22700 nM
|
|
|
|
CP0490635
|
1-(2-naphthalen-2-yloxyethyl)-4-pyridin-2-ylpiperazine
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|
C21H23N3O
|
1
|
| 1 |
IC50 = 23800 nM
|
|
|
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CP0457496
|
1-(4-bromophenyl)-4-(4-naphthalen-2-yloxybutyl)piperazine
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|
C24H27BrN2O
|
1
|
| 1 |
IC50 = 25900 nM
|
|
|
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CP0393337
|
1-(2-methoxyphenyl)-4-(4-naphthalen-2-yloxybutyl)piperazine
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|
C25H30N2O2
|
1
|
| 1 |
IC50 = 29700 nM
|
|
|
|
CP0479626
|
5-(benzhydrylsulfinylmethyl)-4-propan-2-ylthiadiazole
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|
C19H20N2OS2
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0440893
|
5-[[(R)-[(R)-(4-chlorophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14ClNOS2
|
1
|
| 1 |
IC50 = 36500 nM
|
|
|
|
CP0533409
|
5-[[(S)-[(R)-(4-chlorophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14ClNOS2
|
1
|
| 1 |
IC50 = 38600 nM
|
|
|
|
CP0374158
|
N-butyl-N-piperidin-4-ylnaphthalene-2-sulfonamide
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|
C19H26N2O2S
|
1
|
| 1 |
IC50 = 40000 nM
|
|
|
|
CP0387988
|
N-piperidin-4-yl-N-propylnaphthalene-2-carboxamide
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0430823
|
N-cyclobutyl-N-piperidin-4-ylnaphthalene-2-carboxamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
|
CP0002071
|
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
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|
C17H22N2O
|
3
|
| 1 |
IC50 = 42657.95 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
| 3 |
Ki = 12008 nM
|
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CP0534155
|
5-[bis(4-chlorophenyl)methylsulfinylmethyl]-1,3-thiazole
Show/Hide
|
C17H13Cl2NOS2
|
1
|
| 1 |
IC50 = 45490 nM
|
|
|
|
CP0475252
|
4-[[(R)-[(R)-(4-bromophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14BrNOS2
|
1
|
| 1 |
IC50 = 52560 nM
|
|
|
|
CP0458619
|
3-(benzhydrylsulfinylmethyl)thiophene
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|
C18H16OS2
|
1
|
| 1 |
IC50 = 57600 nM
|
|
|
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CP0533897
|
4-(benzhydrylsulfinylmethyl)-2-bromothiophene
Show/Hide
|
C18H15BrOS2
|
1
|
| 1 |
IC50 = 67200 nM
|
|
|
|
CP0475246
|
5-[[(S)-[(R)-(4-bromophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14BrNOS2
|
1
|
| 1 |
IC50 = 67800 nM
|
|
|
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CP0558503
|
5-[[(R)-[(R)-(4-methylphenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C18H17NOS2
|
1
|
| 1 |
IC50 = 68200 nM
|
|
|
|
CP0535519
|
2-(benzhydrylsulfinylmethyl)-5-chlorothiophene
Show/Hide
|
C18H15ClOS2
|
1
|
| 1 |
IC50 = 68400 nM
|
|
|
|
CP0410588
|
5-(benzhydrylsulfinylmethyl)-3-(trifluoromethyl)-1,2,4-oxadiazole
Show/Hide
|
C17H13F3N2O2S
|
1
|
| 1 |
IC50 = 71000 nM
|
|
|
|
CP0476555
|
5-[[(S)-[(S)-(4-chlorophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14ClNOS2
|
1
|
| 1 |
IC50 = 72000 nM
|
|
|
|
CP0440901
|
4-[[(S)-[(S)-(4-bromophenyl)-phenylmethyl]sulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H14BrNOS2
|
1
|
| 1 |
IC50 = 73250 nM
|
|
|
|
CP0438487
|
5-[[(S)-bis(4-fluorophenyl)methylsulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H13F2NOS2
|
1
|
| 1 |
IC50 = 85000 nM
|
|
|
|
CP0510785
|
5-(benzhydrylsulfinylmethyl)-3H-1,3,4-thiadiazol-2-one
Show/Hide
|
C16H14N2O2S2
|
1
|
| 1 |
IC50 = 85700 nM
|
|
|
|
CP0531010
|
5-[[(S)-bis(4-chlorophenyl)methylsulfinyl]methyl]-1,3-thiazole
Show/Hide
|
C17H13Cl2NOS2
|
1
|
| 1 |
IC50 = 89800 nM
|
|
|
|
CP0037306
|
4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one
Show/Hide
|
C16H18N2O3
|
2
|
| 1 |
IC50 > 100000 nM
|
|
|
| 2 |
Ki > 100000 nM
|
|
|
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CP0339911
|
2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1-one
Show/Hide
|
C21H27BrN2O3
|
2
|
| 1 |
IC50 > 100000 nM
|
|
|
| 2 |
Ki = 39119 nM
|
|
|
|
CP0277281
|
(cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Show/Hide
|
C16H18N2O3
|
2
|
| 1 |
IC50 > 100000 nM
|
|
|
| 2 |
Ki > 100000 nM
|
|
|
|
CP0345011
|
(cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Show/Hide
|
C21H27BrN2O3
|
2
|
| 1 |
IC50 > 100000 nM
|
|
|
| 2 |
Ki = 39119 nM
|
|
|
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CP0000059
|
(+/-)3,5,5-Trimethyl-2-(pyridin-3-yl)morpholin-2-ol
Show/Hide
|
C12H18N2O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0000199
|
(2S,3S)-2-(4-Methoxyphenyl)-3,5,5-trimethylmorpholin-2-ol
Show/Hide
|
C14H21NO3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0374754
|
1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-phenethyl-piperazin-2-one
Show/Hide
|
C27H28F2N2O2
|
2
|
| 1 |
IC50 > 10 nM
|
|
|
| 2 |
Ki = 7050 nM
|
|
|
|
CP0440936
|
4-(2-Benzhydryloxy-ethyl)-1-(3-phenyl-propyl)-piperazin-2-one
Show/Hide
|
C28H32N2O2
|
2
|
| 1 |
IC50 > 10 nM
|
|
|
| 2 |
Ki = 5850 nM
|
|
|
|
CP0857795
|
N-((E)-2-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethylamino}-vinyl)-2-(4-bromo-phenyl)-acetamide
Show/Hide
|
C26H25BrF2N2O2
|
2
|
| 1 |
IC50 > 10 nM
|
|
|
| 2 |
Ki = 1760 nM
|
|
|
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CP0000310
|
2-(N-tert-Butylamino)-1-(2'-thienyl)-1-propanone
Show/Hide
|
C11H17NOS
|
2
|
| 1 |
IC50 > 100 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0000434
|
2-(N-Cyclopentylamino)-3'-nitropropiophenone
Show/Hide
|
C14H18N2O3
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0000444
|
3-(tert-butylamino)-1-(3-chlorophenyl)-2-methylpropan-1-one
Show/Hide
|
C14H20ClNO
|
2
|
| 1 |
IC50 > 100 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0000906
|
2-(tert-butylamino)-1-(3-methoxyphenyl)propan-1-one
Show/Hide
|
C14H21NO2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0005770
|
2-(N-tert-Butylamino)-3'-nitropropiophenone
Show/Hide
|
C13H18N2O3
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0387769
|
(S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)pivalamide
Show/Hide
|
C16H22Cl2N2O
|
1
|
| 1 |
IC50 > 322 nM
|
|
|
|
CP0064065
|
4-(2,4-dichlorophenoxy)-3-(methylaminomethyl)benzonitrile
Show/Hide
|
C15H12Cl2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0339409
|
4-(4-chloro-2-methoxyphenoxy)-3-(methylaminomethyl)benzonitrile
Show/Hide
|
C16H15ClN2O2
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0393799
|
1-(1-phenyl-2-(pyridin-4-yl)ethyl)piperazine
Show/Hide
|
C17H21N3
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0393802
|
1-(1-phenyl-2-(pyridin-2-yl)ethyl)piperazine
Show/Hide
|
C17H21N3
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0407216
|
1-(1,3-diphenylpropyl)piperazine
Show/Hide
|
C19H24N2
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0407222
|
1-(2-(naphthalen-1-yl)-1-phenylethyl)piperazine
Show/Hide
|
C22H24N2
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0407223
|
1-(2-(2,4-dichlorophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C18H20Cl2N2
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0456426
|
1-(2-(naphthalen-2-yl)-1-phenylethyl)piperazine
Show/Hide
|
C22H24N2
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0394311
|
1-[4-(4-fluoro-2-methylphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C15H17FN2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0394678
|
3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0394681
|
1-(1-phenyl-2-(3-(trifluoromethyl)phenyl)ethyl)piperazine
Show/Hide
|
C19H21F3N2
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0394682
|
2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0457465
|
4-[(2,4-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0457466
|
2-[(2,3-dichlorophenoxy)-piperidin-4-ylmethyl]-3-methylpyridine
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0491636
|
3-[(3,5-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0496231
|
2-[(2,4-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0496234
|
3-[(2,4-dichlorophenoxy)-piperidin-4-ylmethyl]pyridine
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0387767
|
(S)-N-(2,4-difluorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C15H20F2N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0498539
|
(S)-N-(2-fluoro-4-(trifluoromethyl)benzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C16H20F4N2O
|
1
|
| 1 |
IC50 > 400 nM
|
|
|
|
CP0553448
|
1-methyl-4-[3-[(1R)-3-(methylamino)-1-thiophen-2-ylpropoxy]phenyl]-1,4-diazepan-5-one
Show/Hide
|
C20H27N3O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0372373
|
5-(3,4-dimethoxyphenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,3-thiazole
Show/Hide
|
C26H30N2O2S
|
2
|
| 1 |
IC50 > 6900 nM
|
|
|
| 2 |
Ki = 1390 nM
|
|
|
|
CP0440663
|
(2S,3S)-2-[alpha-(2-Methylphenylthio)phenylmethyl]morpholine
Show/Hide
|
C18H21NOS
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0168013
|
(2S,3S)-2-[alpha-(2-methoxyphenylthio)phenylmethyl]morpholine
Show/Hide
|
C18H21NO2S
|
1
|
| 1 |
Ki = 0.76 nM
|
|
|
|
CP0378312
|
(S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C18H21NO3
|
1
|
| 1 |
Ki = 0.95 nM
|
|
|
|
CP0441135
|
(2S)-2-[(S)-[2-(2-fluoroethoxy)phenyl]sulfanyl-phenylmethyl]morpholine
Show/Hide
|
C19H22FNO2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0373840
|
4-(4,5-difluoro-2-(4-fluorophenoxy)phenyl)piperidine
Show/Hide
|
C17H16F3NO
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0386188
|
(2S,3S)-2-[alpha-(2-Methylphenoxy)phenylmethyl]morpholine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
Ki = 1.02 nM
|
|
|
|
CP0510687
|
(2S)-2-[(S)-[2-(3-fluoropropoxy)phenyl]sulfanyl-phenylmethyl]morpholine
Show/Hide
|
C20H24FNO2S
|
1
|
| 1 |
Ki = 1.21 nM
|
|
|
|
CP0516497
|
methyl 2-[(S)-[(2S)-morpholin-2-yl]-phenylmethoxy]benzoate
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
Ki = 1.32 nM
|
|
|
|
CP0496613
|
methyl 2-[(S)-[(2S)-morpholin-2-yl]-phenylmethyl]sulfanylbenzoate
Show/Hide
|
C19H21NO3S
|
1
|
| 1 |
Ki = 1.35 nM
|
|
|
|
CP0394726
|
(1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C16H20FNO2
|
1
|
| 1 |
Ki = 1.78 nM
|
|
|
|
CP0500871
|
(1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C17H19NO2
|
1
|
| 1 |
Ki = 1.86 nM
|
|
|
|
CP0400049
|
(1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylate
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C15H18INO2
|
1
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| 1 |
Ki = 1.98 nM
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CP0418657
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4-(5-fluoro-2-(4-fluorobenzyloxy)phenyl)piperidine
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C18H19F2NO
|
1
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| 1 |
Ki = 2 nM
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CP0393058
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(2S)-2-[(S)-(2-methylsulfanylphenoxy)-phenylmethyl]morpholine
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C18H21NO2S
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1
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| 1 |
Ki = 2.06 nM
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CP0418855
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3-[4-((Z)-2-Bromo-vinyl)-phenyl]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
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C17H20BrNO2
|
1
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| 1 |
Ki = 2.5 nM
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CP0485209
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3-(4-bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0.0*4,8*]decane
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C16H18BrN
|
1
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| 1 |
Ki = 2.94 nM
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CP0102919
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(S)-2-phenoxy-N-phenyl-N-(pyrrolidin-3-yl)benzamide
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C23H22N2O2
|
1
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| 1 |
Ki = 3 nM
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CP0373805
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4-(2-(2-fluoro-5-methylphenoxy)phenyl)piperidine
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C18H20FNO
|
1
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| 1 |
Ki = 3 nM
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CP0455936
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(2S,3S)-2-[alpha-(2-(2-Fluoroethyl)phenoxy)phenylmethyl]morpholine
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C19H22FNO2
|
1
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| 1 |
Ki = 3.14 nM
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CP0239553
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2-[(3S)-3-(3,4-dichlorophenyl)piperidin-3-yl]ethanol
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C13H17Cl2NO
|
1
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| 1 |
Ki = 3.3 nM
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CP0389644
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(2S,3S)-2-[alpha-(2-(3-Fluoropropyl)phenoxy)phenylmethyl]morpholine
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C20H24FNO2
|
1
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| 1 |
Ki = 3.68 nM
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CP0050766
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(S)-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
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C16H18N2
|
1
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| 1 |
Ki = 4 nM
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CP0262846
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2-[(3R)-3-(1-benzofuran-2-yl)piperidin-3-yl]ethanol
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C15H19NO2
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1
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| 1 |
Ki = 4 nM
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CP0405444
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(1R,2S,3R,5R)-methyl 3-(4-vinylphenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylate
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C17H21NO2
|
1
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| 1 |
Ki = 4.67 nM
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CP0390490
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3-(4-chloro-phenyl)-5-methylene-7-aza-tricyclo[5.3.0.0*4,8*]decane
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C16H18ClN
|
1
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| 1 |
Ki = 4.84 nM
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CP0400050
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(1R,2S,3R,5R)-methyl 3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate
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C16H21NO2
|
1
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| 1 |
Ki = 4.88 nM
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CP0493327
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2-(2-Dimethylaminomethyl-phenylsulfanyl)-phenylamine
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C15H18N2S
|
1
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| 1 |
Ki = 4.95 nM
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CP0254258
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(S)-N-cyclohexyl-2-(methylthio)-N-(pyrrolidin-3-yl)benzamide
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C18H26N2OS
|
1
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| 1 |
Ki = 5 nM
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CP0439215
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4-(3,4-dichlorophenyl)-2-(2-(piperazin-1-yl)benzyl)thiomorpholin-3-one
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C21H23Cl2N3OS
|
1
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| 1 |
Ki = 5 nM
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CP0071199
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]methanesulfonamide
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C18H22N2O2S
|
1
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| 1 |
Ki = 5 nM
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CP0293563
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]ethanesulfonamide
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C19H24N2O2S
|
1
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| 1 |
Ki = 5 nM
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CP0208586
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2-[(3S)-3-(3,4-dichlorophenyl)azepan-3-yl]ethanol
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C14H19Cl2NO
|
1
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| 1 |
Ki = 5.1 nM
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CP0405028
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3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
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C17H19Br2NO2
|
1
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| 1 |
Ki = 5.6 nM
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CP0393858
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3-(4-iodo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0.0*4,8*]decane
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C16H18IN
|
1
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| 1 |
Ki = 5.87 nM
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CP0710774
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(S)-2-((S)-(4-fluoro-2-methoxyphenoxy)(phenyl)methyl)morpholine
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C18H20FNO3
|
1
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| 1 |
Ki = 6 nM
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CP0070614
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(S)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
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C17H21F3N2O
|
1
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| 1 |
Ki = 6 nM
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CP0262293
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(S)-N-(cyclobutylmethyl)-2-(ethylthio)-N-(pyrrolidin-3-yl)benzamide
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C18H26N2OS
|
1
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| 1 |
Ki = 6 nM
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CP0439216
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4-(5-chloro-2-(4-fluorobenzyloxy)phenyl)piperidine
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C18H19ClFNO
|
1
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| 1 |
Ki = 6 nM
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CP0844803
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5-(2-benzylpiperazin-1-yl)-7-fluoro-1H-indole
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C19H20FN3
|
1
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| 1 |
Ki = 6.31 nM
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CP0254255
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(S)-N-(cyclobutylmethyl)-2-phenoxy-N-(pyrrolidin-3-yl)benzamide
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C22H26N2O2
|
1
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| 1 |
Ki = 7 nM
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CP0265054
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propane-1-sulfonamide
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C20H26N2O2S
|
1
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| 1 |
Ki = 7 nM
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CP0480686
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3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
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C15H18INO2
|
1
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| 1 |
Ki = 7.5 nM
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CP0302438
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N-benzyl-N-piperidin-4-yl-1H-indol-5-amine
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C20H23N3
|
1
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| 1 |
Ki = 7.943 nM
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CP0899719
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5-(2-benzylpiperazin-1-yl)-1H-indole
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C19H21N3
|
1
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| 1 |
Ki = 7.943 nM
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CP0646524
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(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(phenyl)methyl)morpholine
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C18H20ClNO3
|
1
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| 1 |
Ki = 8 nM
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CP0036508
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(S)-ethyl biphenyl-2-ylmethyl(pyrrolidin-3-yl)carbamate
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C20H24N2O2
|
1
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| 1 |
Ki = 8 nM
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CP0207001
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(S)-N-isobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamide
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C21H26N2O2
|
1
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| 1 |
Ki = 8 nM
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CP0299494
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(S)-N-(cyclobutylmethyl)-2-(methylthio)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C17H24N2OS
|
1
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| 1 |
Ki = 8 nM
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CP0320397
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(3S)-N-(dimethylsulfamoyl)-N-[(2-phenylphenyl)methyl]pyrrolidin-3-amine
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C19H25N3O2S
|
1
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| 1 |
Ki = 8 nM
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CP0902808
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(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(3-fluorophenyl)methyl)morpholine
Show/Hide
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C18H19ClFNO3
|
1
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| 1 |
Ki = 9 nM
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CP0070611
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(S)-N-cyclopentyl-2-(methylthio)-N-(pyrrolidin-3-yl)benzamide
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C17H24N2OS
|
1
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| 1 |
Ki = 9 nM
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CP0302452
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(S)-N-ethyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamide
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C19H22N2O2
|
1
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| 1 |
Ki = 9 nM
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CP0419041
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4-(2-(benzyloxy)-3-fluorophenyl)piperidine
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C18H20FNO
|
1
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| 1 |
Ki = 9 nM
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CP0439218
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4-(2-(benzyloxy)-6-fluorophenyl)piperidine
Show/Hide
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C18H20FNO
|
1
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| 1 |
Ki = 9 nM
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CP0102975
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N-methyl-1-[6-methyl-4-(2-phenoxyphenoxy)pyridin-3-yl]methanamine
Show/Hide
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C20H20N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0364822
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N,N-dimethyl-1-[6-methyl-4-(2-phenoxyphenoxy)pyridin-3-yl]methanamine
Show/Hide
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C21H22N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0830568
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(S)-2-((S)-(2,3-difluorophenoxy)(phenyl)methyl)morpholine
Show/Hide
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C17H17F2NO2
|
1
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| 1 |
Ki = 10 nM
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CP0259677
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(S)-N-(cyclobutylmethyl)-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C19H28N2O
|
1
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| 1 |
Ki = 10 nM
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CP0166298
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(S)-2,3-dichloro-N-(2H-pyran-4-yl)-N-(pyrrolidin-3-yl)benzamide
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C16H16Cl2N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0388339
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propane-2-sulfonamide
Show/Hide
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C20H26N2O2S
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1
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| 1 |
Ki = 10 nM
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CP0204254
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(S)-2,3-dichloro-N-phenyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C17H16Cl2N2O
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1
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| 1 |
Ki = 11 nM
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CP0278073
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(S)-2,3-dichloro-N-cyclopentyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C16H20Cl2N2O
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1
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| 1 |
Ki = 11 nM
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CP0066194
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N-[2-(1,3-benzodioxol-5-yl)ethyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropan-1-amine
Show/Hide
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C28H33NO4
|
1
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| 1 |
Ki = 11 nM
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CP0806390
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(S)-2-((S)-(2,3-dihydrobenzofuran-7-yloxy)(phenyl)methyl)morpholine
Show/Hide
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C19H21NO3
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1
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| 1 |
Ki = 12 nM
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CP0807128
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(S)-2-((S)-(2-chloro-4-fluorophenoxy)(phenyl)methyl)morpholine
Show/Hide
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C17H17ClFNO2
|
1
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| 1 |
Ki = 12 nM
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CP0877382
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(S)-2-((S)-(4-bromo-2-methoxyphenoxy)(phenyl)methyl)morpholine
Show/Hide
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C18H20BrNO3
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1
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| 1 |
Ki = 12 nM
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CP0239558
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(3R)-3-(3,4-dichlorophenyl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
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C13H15Cl2N
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1
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| 1 |
Ki = 12 nM
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CP0261048
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2-[(3R)-3-(3,4-dichlorophenyl)-2,3,4,7-tetrahydroazepin-1-yl]ethanol
Show/Hide
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C14H17Cl2NO
|
1
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| 1 |
Ki = 12 nM
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CP0500003
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methyl (2E)-2-[3-(4-bromophenyl)-7-azatricyclo[5.3.0.04,8]decan-5-ylidene]acetate
Show/Hide
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C18H20BrNO2
|
1
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| 1 |
Ki = 12.53 nM
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CP0859159
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5-(2-benzylpiperazin-1-yl)-7-chloro-1H-indole
Show/Hide
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C19H20ClN3
|
1
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| 1 |
Ki = 12.59 nM
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CP0339531
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N,N-dimethyl-1-[6-methyl-4-(2-propan-2-ylphenoxy)pyridin-3-yl]methanamine
Show/Hide
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C18H24N2O
|
1
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| 1 |
Ki = 13 nM
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CP0208390
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(S)-N-cyclobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C21H24N2O2
|
1
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| 1 |
Ki = 13 nM
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CP0383349
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(S)-2,3-dichloro-N-neopentyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C16H22Cl2N2O
|
1
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| 1 |
Ki = 13 nM
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CP0458103
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methyl (2E)-2-[3-(4-chlorophenyl)-7-azatricyclo[5.3.0.04,8]decan-5-ylidene]acetate
Show/Hide
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C18H20ClNO2
|
1
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| 1 |
Ki = 13.03 nM
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CP0372644
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Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic acid isopropyl ester
Show/Hide
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C21H26N2O2
|
1
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| 1 |
Ki = 14 nM
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CP0239554
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(3R)-3-(3,4-dichlorophenyl)-1-(2-methoxyethyl)-2,3,4,7-tetrahydroazepine
Show/Hide
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C15H19Cl2NO
|
1
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| 1 |
Ki = 15 nM
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CP0899718
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2-benzyl-1-(3,4-dichlorophenyl)piperazine
Show/Hide
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C17H18Cl2N2
|
1
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| 1 |
Ki = 15.85 nM
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CP0855224
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(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(m-tolyl)methyl)morpholine
Show/Hide
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C19H22ClNO3
|
1
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| 1 |
Ki = 16 nM
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CP0207000
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(S)-N-cyclobutyl-2-(methylthio)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C16H22N2OS
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1
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| 1 |
Ki = 16 nM
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CP0293564
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Biphenyl-2-ylmethyl-(R)-pyrrolidin-3-yl-carbamic acid ethyl ester
Show/Hide
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C20H24N2O2
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1
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| 1 |
Ki = 16 nM
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CP0862104
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(S)-2-((S)-(2,3-dichlorophenoxy)(phenyl)methyl)morpholine
Show/Hide
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C17H17Cl2NO2
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1
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| 1 |
Ki = 17 nM
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CP0333998
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(3R)-3-(3,4-dichlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
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C12H13Cl2N
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1
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| 1 |
Ki = 17 nM
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CP0192645
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5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decane
Show/Hide
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C17H21N
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1
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| 1 |
Ki = 17.28 nM
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CP0830569
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(S)-2-((S)-(4-fluoro-2-methylphenoxy)(phenyl)methyl)morpholine
Show/Hide
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C18H20FNO2
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1
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| 1 |
Ki = 18 nM
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CP0048947
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(S)-N-(cyclobutylmethyl)-2-cyclopentyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C21H30N2O
|
1
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| 1 |
Ki = 18 nM
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CP0070613
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(S)-N-(cyclopentylmethyl)-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C20H30N2O
|
1
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| 1 |
Ki = 18 nM
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CP0394160
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Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic acid methyl ester
Show/Hide
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C19H22N2O2
|
1
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| 1 |
Ki = 18 nM
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CP0254257
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(S)-2-(methylthio)-N-phenyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C18H20N2OS
|
1
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| 1 |
Ki = 19 nM
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CP0298170
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(S)-2-chloro-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C16H21ClN2O
|
1
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| 1 |
Ki = 19 nM
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CP0317015
|
5-(2-isobutylpiperazin-1-yl)-1H-indazole
Show/Hide
|
C15H22N4
|
1
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| 1 |
Ki = 19.95 nM
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CP0438748
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4-(2-(3,4-dichlorobenzyloxy)-5-fluorophenyl)piperidine
Show/Hide
|
C18H18Cl2FNO
|
1
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| 1 |
Ki = 20 nM
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CP0035727
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(S)-2,3-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C15H20Cl2N2O
|
1
|
| 1 |
Ki = 21 nM
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CP0373819
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4-(2-(4-fluorophenoxy)phenyl)piperidine
Show/Hide
|
C17H18FNO
|
1
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| 1 |
Ki = 21 nM
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CP0855368
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(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(2-fluorophenyl)methyl)morpholine
Show/Hide
|
C18H19ClFNO3
|
1
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| 1 |
Ki = 22 nM
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CP0167544
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(S)-N-(cyclobutylmethyl)-2-ethoxy-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C18H26N2O2
|
1
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| 1 |
Ki = 22 nM
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CP0107801
|
1-(2-(2-cyclopropoxyphenyl)-1-phenylethyl)piperazine
Show/Hide
|
C21H26N2O
|
1
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| 1 |
Ki = 22 nM
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CP0307654
|
1-(2-(2-isopropoxyphenyl)-1-phenylethyl)piperazine
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
Ki = 22 nM
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CP0317054
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(2-Phenoxy-benzyl)-(S)-pyrrolidin-3-yl-carbamic acid ethyl ester
Show/Hide
|
C20H24N2O3
|
1
|
| 1 |
Ki = 23 nM
|
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CP0136670
|
2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane
Show/Hide
|
C17H20INO2
|
1
|
| 1 |
Ki = 24 nM
|
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CP0102695
|
(S)-N-(cyclopentylmethyl)-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
Show/Hide
|
C18H23F3N2O
|
1
|
| 1 |
Ki = 24 nM
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CP0239888
|
(S)-2,3-dichloro-N-(2-cyclopropylethyl)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C16H20Cl2N2O
|
1
|
| 1 |
Ki = 24 nM
|
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CP0262848
|
(3S)-3-(3,4-dichlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H13Cl2N
|
1
|
| 1 |
Ki = 24 nM
|
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CP0305750
|
1-(2-(2-(cyclopropylmethoxy)phenyl)-1-phenylethyl)piperazine
Show/Hide
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C22H28N2O
|
1
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| 1 |
Ki = 25 nM
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CP0394161
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]butanamide
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C21H26N2O
|
1
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| 1 |
Ki = 25 nM
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CP0341711
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2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine
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C16H16Cl2N2O
|
1
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| 1 |
Ki = 25 nM
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CP0239557
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3-naphthalen-2-yl-2,3,4,7-tetrahydro-1H-azepine
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C16H17N
|
1
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| 1 |
Ki = 25 nM
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CP0335946
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5-(2-benzylpiperazin-1-yl)-1H-indazole
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C18H20N4
|
1
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| 1 |
Ki = 25.12 nM
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CP0390492
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methyl (2E)-2-[3-(4-methylphenyl)-7-azatricyclo[5.3.0.04,8]decan-5-ylidene]acetate
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C19H23NO2
|
1
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| 1 |
Ki = 25.5 nM
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CP0430340
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(S)-3-fluoro-N-isobutyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
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C16H20F4N2O
|
1
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| 1 |
Ki = 26 nM
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CP0107804
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1-(2-(2-(difluoromethoxy)phenyl)-1-(3-fluorophenyl)ethyl)piperazine
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C19H21F3N2O
|
1
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| 1 |
Ki = 26 nM
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CP0286938
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1-[4-(2-ethylphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
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C17H22N2O
|
1
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| 1 |
Ki = 27 nM
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CP0325344
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1-(2-(2-fluoro-6-methoxyphenyl)-1-phenylethyl)piperazine
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C19H23FN2O
|
1
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| 1 |
Ki = 27 nM
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CP0437706
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]pyrrolidine-1-carboxamide
Show/Hide
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C22H27N3O
|
1
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| 1 |
Ki = 27 nM
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CP0221618
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2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
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C17H19FN2O
|
1
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| 1 |
Ki = 27 nM
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CP0906294
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(S)-2-((S)-(2-chloro-4-methoxyphenoxy)(phenyl)methyl)morpholine
Show/Hide
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C18H20ClNO3
|
1
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| 1 |
Ki = 28 nM
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CP0868586
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2-beta-carbo(2-[18F]fluoroethoxy)-3-beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane
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C18H21FINO2
|
1
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| 1 |
Ki = 28 nM
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CP0048948
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(S)-N-phenyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
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C18H17F3N2O
|
1
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| 1 |
Ki = 28 nM
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CP0873212
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(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(4-fluorophenyl)methyl)morpholine
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C18H19ClFNO3
|
1
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| 1 |
Ki = 29 nM
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CP0195609
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(S)-N-(cyclobutylmethyl)-2-ethyl-N-(pyrrolidin-3-yl)benzamide
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C18H26N2O
|
1
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| 1 |
Ki = 29 nM
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CP0278807
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(S)-3-chloro-N-isobutyl-2-methyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C16H23ClN2O
|
1
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| 1 |
Ki = 29 nM
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CP0082297
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N-[(2-phenylphenyl)methyl]-N-[(3R)-pyrrolidin-3-yl]methanesulfonamide
Show/Hide
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C18H22N2O2S
|
1
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| 1 |
Ki = 29 nM
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CP0152499
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(S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
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C16H19F3N2O
|
1
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| 1 |
Ki = 30 nM
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CP0274998
|
1-(1-(3-fluorophenyl)-2-(2-methoxyphenyl)ethyl)piperazine
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C19H23FN2O
|
1
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| 1 |
Ki = 30 nM
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CP0307657
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1-(1-(3-fluorophenyl)-2-(2-(trifluoromethoxy)phenyl)ethyl)piperazine
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C19H20F4N2O
|
1
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| 1 |
Ki = 30 nM
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CP0388340
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3-methyl-N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]butanamide
Show/Hide
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C22H28N2O
|
1
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| 1 |
Ki = 30 nM
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CP0394159
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1,1,1-trifluoro-N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]methanesulfonamide
Show/Hide
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C18H19F3N2O2S
|
1
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| 1 |
Ki = 30 nM
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CP0394165
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N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propanamide
Show/Hide
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C20H24N2O
|
1
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| 1 |
Ki = 30 nM
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CP0848627
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6-methoxy-2-methyl-3-((R)-3-methyl-1-((S)-pyrrolidin-3-yl)butoxy)pyridine
Show/Hide
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C16H26N2O2
|
1
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| 1 |
Ki = 30 nM
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CP0503553
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2beta-Carbo(2-fluoropropoxy)-3beta-(3'-((Z)-2-bmoroethenyl)phenyl)-nortropane
Show/Hide
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C19H23BrFNO2
|
1
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| 1 |
Ki = 30.2 nM
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CP0254259
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(S)-N-(cyclopropylmethyl)-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
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C18H26N2O
|
1
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| 1 |
Ki = 31 nM
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CP0231711
|
(S)-5-(2-propylpiperazin-1-yl)-1H-indazole
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C14H20N4
|
1
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| 1 |
Ki = 31.62 nM
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CP0102696
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(S)-N-cyclopentyl-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
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C19H28N2O
|
1
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| 1 |
Ki = 32 nM
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CP0055758
|
4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine
Show/Hide
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C17H17F2NO
|
1
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| 1 |
Ki = 32 nM
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CP0083053
|
2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
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C16H16ClFN2O
|
1
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| 1 |
Ki = 33 nM
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CP0396950
|
4-(2-(2-fluorobenzyloxy)phenyl)piperidine
Show/Hide
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C18H20FNO
|
1
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| 1 |
Ki = 34 nM
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CP0422026
|
(S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
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C21H26N2O2
|
1
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| 1 |
Ki = 34 nM
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CP0048839
|
(2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate
Show/Hide
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C16H20INO2
|
1
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| 1 |
Ki = 36 nM
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CP0289546
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(S)-2,3-dichloro-N-propyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C14H18Cl2N2O
|
1
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| 1 |
Ki = 36 nM
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CP0254256
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(S)-2-(methylthio)-N-propyl-N-(pyrrolidin-3-yl)benzamide
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C15H22N2OS
|
1
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| 1 |
Ki = 37 nM
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CP0332170
|
(S)-2,3-dichloro-N-(pentan-3-yl)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C16H22Cl2N2O
|
1
|
| 1 |
Ki = 37 nM
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CP0360517
|
(S)-2,4-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C15H20Cl2N2O
|
1
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| 1 |
Ki = 37 nM
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CP0916346
|
2-(2-Methylaminomethyl-phenylsulfanyl)-phenylamine
Show/Hide
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C14H12N2O3S
|
1
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| 1 |
Ki = 37.52 nM
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CP0089316
|
(R)-N-(cyclobutylmethyl)-2-phenoxy-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
Ki = 38 nM
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CP0744829
|
5-(2-propylpiperazin-1-yl)-1H-indazole
Show/Hide
|
C14H20N4
|
1
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| 1 |
Ki = 39.81 nM
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CP0264872
|
1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl)ethyl)piperazine
Show/Hide
|
C19H21F3N2O
|
1
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| 1 |
Ki = 40 nM
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CP0276400
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(S)-N-cyclobutyl-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C18H26N2O
|
1
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| 1 |
Ki = 43 nM
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CP0298966
|
(S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C15H20Cl2N2O
|
1
|
| 1 |
Ki = 43 nM
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CP0294254
|
1-(2-(2-(difluoromethoxy)phenyl)-1-(2-fluorophenyl)ethyl)piperazine
Show/Hide
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C19H21F3N2O
|
1
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| 1 |
Ki = 46 nM
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CP0388343
|
(S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-carbamic acid ethyl ester
Show/Hide
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C15H19F3N2O2
|
1
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| 1 |
Ki = 46 nM
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CP0208587
|
3-(1-benzofuran-2-yl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C14H15NO
|
1
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| 1 |
Ki = 46 nM
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CP0490847
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(2-Isopropyl-benzyl)-(S)-pyrrolidin-3-yl-carbamic acid ethyl ester
Show/Hide
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C17H26N2O2
|
1
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| 1 |
Ki = 49 nM
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CP0285758
|
2-[(3R)-3-(3,4-dichlorophenyl)azepan-3-yl]ethanol
Show/Hide
|
C14H19Cl2NO
|
1
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| 1 |
Ki = 49 nM
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CP0364308
|
(S)-3,4-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
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C15H20Cl2N2O
|
1
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| 1 |
Ki = 50 nM
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CP0844802
|
5-(2-benzylpiperazin-1-yl)-1-methyl-1H-indole
Show/Hide
|
C20H23N3
|
1
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| 1 |
Ki = 50.12 nM
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CP0903356
|
5-(2-benzylpiperazin-1-yl)-7-methoxy-1H-indole
Show/Hide
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C20H23N3O
|
1
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| 1 |
Ki = 50.12 nM
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CP0504328
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1-Biphenyl-2-ylmethyl-3,3-dimethyl-1-(S)-pyrrolidin-3-yl-urea
Show/Hide
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C20H25N3O
|
1
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| 1 |
Ki = 53 nM
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CP0334041
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(3S)-3-(3,4-dichlorophenyl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
|
C13H15Cl2N
|
1
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| 1 |
Ki = 54 nM
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CP0704391
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rac-3-(3,4-Dichloro-phenyl)-1-methyl-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C13H15Cl2N
|
1
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| 1 |
Ki = 57 nM
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CP0427825
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N,N-dimethyl-1-[6-methyl-4-(2-methylsulfanylphenoxy)pyridin-3-yl]methanamine
Show/Hide
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C16H20N2OS
|
1
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| 1 |
Ki = 58 nM
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CP0270319
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1-(2-(2-(difluoromethoxy)-6-fluorophenyl)-1-phenylethyl)piperazine
Show/Hide
|
C19H21F3N2O
|
1
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| 1 |
Ki = 58 nM
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CP0307652
|
(R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol
Show/Hide
|
C18H22N2O
|
1
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| 1 |
Ki = 58 nM
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CP0070612
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(S)-N-cyclobutyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
Show/Hide
|
C16H19F3N2O
|
1
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| 1 |
Ki = 60 nM
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CP0104534
|
2-(2-((dimethylamino)methyl)phenylthio)-5-methylaniline
Show/Hide
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C16H20N2S
|
3
|
| 1 |
Ki = 61 nM
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| 2 |
Ki = 320.4 nM
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| 3 |
Ki = 325 nM
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CP0167545
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(S)-N-methyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C18H20N2O2
|
1
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| 1 |
Ki = 61 nM
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CP0372645
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2-methyl-N-[(3S)-pyrrolidin-3-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C16H21F3N2O
|
1
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| 1 |
Ki = 63 nM
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CP0150341
|
(S)-N-isobutyl-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C18H28N2O
|
1
|
| 1 |
Ki = 65 nM
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CP0422025
|
(S)-N-(2-(methylthio)benzyl)-N-(pyrrolidin-3-yl)isobutyramide
Show/Hide
|
C16H24N2OS
|
1
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| 1 |
Ki = 65 nM
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CP0770079
|
rac-3-(3,4-Dichloro-phenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H13Cl2N
|
1
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| 1 |
Ki = 66 nM
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CP0353991
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(S)-2-chloro-3-fluoro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H20ClFN2O
|
1
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| 1 |
Ki = 67 nM
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CP0423166
|
2beta-Carbo(2-fluoropropoxy)-3beta-(3'-((Z)-2-iodoethenyl)phenyl)-nortropane
Show/Hide
|
C19H23FINO2
|
1
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| 1 |
Ki = 67.5 nM
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CP0204256
|
(S)-3-fluoro-N-isobutyl-2-methyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C16H23FN2O
|
1
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| 1 |
Ki = 69 nM
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CP0422027
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2-methyl-N-[(2-propan-2-ylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propanamide
Show/Hide
|
C18H28N2O
|
1
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| 1 |
Ki = 70 nM
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CP0534821
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methyl (1R,2S,3S)-3-(4-(125I)iodanylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C16H20INO2
|
1
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| 1 |
Ki = 70 nM
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CP0167541
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(S)-N-(cyclobutylmethyl)-2-methyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C17H24N2O
|
1
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| 1 |
Ki = 72 nM
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CP0388341
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N-[(2-cyclopropylphenyl)methyl]-2-methyl-N-[(3S)-pyrrolidin-3-yl]propanamide
Show/Hide
|
C18H26N2O
|
1
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| 1 |
Ki = 74 nM
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CP0101712
|
2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H17ClN2O
|
1
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| 1 |
Ki = 74 nM
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CP0285760
|
3-(3,4-dichlorophenyl)-1-methylazepane
Show/Hide
|
C13H17Cl2N
|
1
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| 1 |
Ki = 74 nM
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CP0373798
|
4-(2-(benzyloxy)phenyl)piperidine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 76 nM
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CP0198450
|
1-[5,5-bis(4-fluorophenyl)pentyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
Show/Hide
|
C29H29ClF5NO
|
1
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| 1 |
Ki = 77 nM
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CP0278569
|
5-(2-phenethylpiperazin-1-yl)-1H-indazole
Show/Hide
|
C19H22N4
|
1
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| 1 |
Ki = 79.43 nM
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CP0335945
|
5-(2-butylpiperazin-1-yl)-1H-indazole
Show/Hide
|
C15H22N4
|
1
|
| 1 |
Ki = 79.43 nM
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CP0373807
|
1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazine
Show/Hide
|
C17H18F2N2O
|
1
|
| 1 |
Ki = 80 nM
|
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CP0427824
|
N-methyl-1-[6-methyl-4-(2-propan-2-ylphenoxy)pyridin-3-yl]methanamine
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki = 82 nM
|
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CP0261049
|
3-(3-chloro-4-methylphenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C13H16ClN
|
1
|
| 1 |
Ki = 83 nM
|
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CP0869855
|
(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(o-tolyl)methyl)morpholine
Show/Hide
|
C19H22ClNO3
|
1
|
| 1 |
Ki = 84 nM
|
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CP0071591
|
1-(2-(3-fluoro-2-methoxyphenyl)-1-phenylethyl)piperazine
Show/Hide
|
C19H23FN2O
|
1
|
| 1 |
Ki = 84 nM
|
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CP0394162
|
N-[(2-methylsulfanylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]methanesulfonamide
Show/Hide
|
C13H20N2O2S2
|
1
|
| 1 |
Ki = 86 nM
|
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CP0509084
|
(S)-N-(2-(trifluoromethyl)benzyl)-N-(pyrrolidin-3-yl)methanesulfonamide
Show/Hide
|
C13H17F3N2O2S
|
1
|
| 1 |
Ki = 86 nM
|
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CP0503538
|
(2-Methylsulfanyl-benzyl)-(S)-pyrrolidin-3-yl-carbamic acid ethyl ester
Show/Hide
|
C15H22N2O2S
|
1
|
| 1 |
Ki = 89 nM
|
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CP0148373
|
(S)-2-isopropyl-N-propyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C17H26N2O
|
1
|
| 1 |
Ki = 92 nM
|
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CP0166297
|
(S)-2,3-dichloro-N-(pyrrolidin-3-yl)-N-(2,2,2-trifluoroethyl)benzamide
Show/Hide
|
C13H13Cl2F3N2O
|
1
|
| 1 |
Ki = 95 nM
|
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|
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CP0388342
|
N-[(2-phenoxyphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]methanesulfonamide
Show/Hide
|
C18H22N2O3S
|
1
|
| 1 |
Ki = 96 nM
|
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CP0393213
|
3-[4-(6-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-cyclohexyl]-1H-indole-5-carbonitrile
Show/Hide
|
C25H27N3O
|
1
|
| 1 |
Ki = 96.7 nM
|
|
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CP0373831
|
4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine
Show/Hide
|
C17H17F2NO
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0107803
|
1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)piperazine
Show/Hide
|
C19H23FN2O
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0106979
|
1-(1-(4-fluorophenyl)-2-(2-methoxyphenyl)ethyl)piperazine
Show/Hide
|
C19H23FN2O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0297725
|
(S)-5-(2-((tetrahydro-2H-pyran-4-yl)methyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C17H24N4O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0248165
|
2-benzyl-5-(3-methoxyphenyl)-1,3-dihydroisoindole
Show/Hide
|
C22H21NO
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0428153
|
2beta-Carbo(2-fluoroethoxy)-3beta-(3'-((Z)-2-bromoethenyl)phenyl)-nortropane
Show/Hide
|
C18H21BrFNO2
|
1
|
| 1 |
Ki = 101.3 nM
|
|
|
|
CP0373893
|
3-[4-[6-(3-fluoropropoxy)-3,4-dihydro-1H-isoquinolin-2-yl]cyclohexyl]-1H-indole-5-carbonitrile
Show/Hide
|
C27H30FN3O
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0360518
|
(S)-2-chloro-N-isobutyl-N-(pyrrolidin-3-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C16H20ClF3N2O
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0418608
|
1-(2-((3-fluorophenoxy)methyl)phenyl)piperazine
Show/Hide
|
C17H19FN2O
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0490817
|
3-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-phenyl]-propan-1-ol
Show/Hide
|
C18H24N2OS
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0516044
|
2beta-Carbo(2-fluoroethoxy)-3beta-(3'-((Z)-2-iodoethenyl)phenyl)-nortropane
Show/Hide
|
C18H21FINO2
|
1
|
| 1 |
Ki = 109.9 nM
|
|
|
|
CP0461040
|
3-[4-((Z)-2-Bromo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Show/Hide
|
C18H22BrNO2
|
1
|
| 1 |
Ki = 111 nM
|
|
|
|
CP0373799
|
4-(2-(4-fluorophenoxy)-4-methylphenyl)piperidine
Show/Hide
|
C18H20FNO
|
1
|
| 1 |
Ki = 115 nM
|
|
|
|
CP0502231
|
N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]formamide
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
Ki = 118 nM
|
|
|
|
CP0145994
|
3-(1-benzofuran-2-yl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0490848
|
N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]acetamide
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0711435
|
(R)-2-((R)-(2,3-difluorophenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C17H17F2NO2
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0145943
|
3-(3-chloro-4-fluorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H13ClFN
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0156814
|
3-(3,4-dichlorophenyl)azepane
Show/Hide
|
C12H15Cl2N
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0262847
|
3-(4-chloro-3-methylphenyl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
|
C14H18ClN
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0372743
|
1-[4-(2-chlorophenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
|
C15H17ClN2O
|
1
|
| 1 |
Ki = 131 nM
|
|
|
|
CP0204255
|
(S)-3-chloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H21ClN2O
|
1
|
| 1 |
Ki = 135 nM
|
|
|
|
CP0353992
|
(S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H20ClFN2O
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0327962
|
3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)pyridine
Show/Hide
|
C17H17F3N2O
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0467257
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoro-phenylamine
Show/Hide
|
C15H17FN2S
|
1
|
| 1 |
Ki = 141.7 nM
|
|
|
|
CP0287418
|
2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H16F2N2O
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0167392
|
(S)-N-(pyrrolidin-3-yl)-N-(2-(trifluoromethyl)benzyl)cyclobutanecarboxamide
Show/Hide
|
C17H21F3N2O
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0297724
|
(R)-5-(2-propylpiperazin-1-yl)-1H-indazole
Show/Hide
|
C14H20N4
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0382107
|
N,N-dimethyl-1-[6-methyl-4-(2-propylphenoxy)pyridin-3-yl]methanamine
Show/Hide
|
C18H24N2O
|
1
|
| 1 |
Ki = 159 nM
|
|
|
|
CP0927555
|
(S)-2-((S)-(2-methoxy-4-(trifluoromethyl)phenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C19H20F3NO3
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0460933
|
3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Show/Hide
|
C18H21Br2NO2
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0373801
|
4-(2-(4-fluorobenzyloxy)phenyl)piperidine
Show/Hide
|
C18H20FNO
|
1
|
| 1 |
Ki = 162 nM
|
|
|
|
CP0434548
|
5-(phenoxymethyl)-3-piperazin-1-yl-1,2-oxazole;hydrochloride
Show/Hide
|
C14H18ClN3O2
|
1
|
| 1 |
Ki = 163 nM
|
|
|
|
CP0353993
|
(R)-2,3-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H20Cl2N2O
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0373837
|
4-(2-fluoro-6-phenoxyphenyl)piperidine
Show/Hide
|
C17H18FNO
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0472700
|
4-(2-(3-fluorophenoxy)-4-methylphenyl)piperidine
Show/Hide
|
C18H20FNO
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0239555
|
3-(4-chloro-3-methylphenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C13H16ClN
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0247845
|
(S)-N-isopropyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
Show/Hide
|
C15H19F3N2O
|
1
|
| 1 |
Ki = 172 nM
|
|
|
|
CP0845871
|
6-methoxy-2-methyl-3-((R)-3-methyl-1-((R)-pyrrolidin-3-yl)butoxy)pyridine
Show/Hide
|
C16H26N2O2
|
1
|
| 1 |
Ki = 177 nM
|
|
|
|
CP0382106
|
1-[4-(2-ethoxyphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
|
C17H22N2O2
|
1
|
| 1 |
Ki = 179 nM
|
|
|
|
CP0877616
|
(S)-2-((S)-(4-chloro-2-methoxyphenoxy)(p-tolyl)methyl)morpholine
Show/Hide
|
C19H22ClNO3
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0282528
|
2-(2,6-difluorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H16F2N2O
|
1
|
| 1 |
Ki = 181 nM
|
|
|
|
CP0419039
|
1-(2-(phenoxymethyl)phenyl)piperazine
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 183 nM
|
|
|
|
CP0406269
|
3-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-cyclohexyl]-1H-indole-5-carbonitrile
Show/Hide
|
C24H25N3
|
1
|
| 1 |
Ki = 184 nM
|
|
|
|
CP0335060
|
methyl (1R,2S,3S,5S)-3-(4-methylphenyl)-8-[(Z)-4,4,4-trifluoro-2-iodobut-2-enyl]-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C20H23F3INO2
|
1
|
| 1 |
Ki = 188 nM
|
|
|
|
CP0880322
|
5-Methyl-2-(2-methylaminomethyl-phenylsulfanyl)-phenylamine
Show/Hide
|
C15H14N2O3S
|
1
|
| 1 |
Ki = 191 nM
|
|
|
|
CP0438756
|
1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 192 nM
|
|
|
|
CP0495397
|
2-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-phenyl]-ethanol
Show/Hide
|
C17H22N2OS
|
1
|
| 1 |
Ki = 194 nM
|
|
|
|
CP0422351
|
N,N-dimethyl-1-[6-methyl-4-(2-methylphenoxy)pyridin-3-yl]methanamine
Show/Hide
|
C16H20N2O
|
1
|
| 1 |
Ki = 194 nM
|
|
|
|
CP0353990
|
(S)-2,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H20Cl2N2O
|
1
|
| 1 |
Ki = 198 nM
|
|
|
|
CP0278570
|
5-(2-phenylpiperazin-1-yl)-1H-indazole
Show/Hide
|
C17H18N4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0869918
|
3-methoxy-4-((S)-((S)-morpholin-2-yl)(phenyl)methoxy)benzonitrile
Show/Hide
|
C19H20N2O3
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0336141
|
(S)-2,3-dichloro-N-ethyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C13H16Cl2N2O
|
1
|
| 1 |
Ki = 217 nM
|
|
|
|
CP0431236
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluoro-propyl)-phenylamine
Show/Hide
|
C18H23FN2S
|
2
|
| 1 |
Ki = 219 nM
|
|
|
| 2 |
Ki = 505 nM
|
|
|
|
CP0525680
|
N-methyl-1-[6-methyl-4-(2-methylsulfanylphenoxy)pyridin-3-yl]methanamine
Show/Hide
|
C15H18N2OS
|
1
|
| 1 |
Ki = 232 nM
|
|
|
|
CP0038260
|
3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid phenyl ester
Show/Hide
|
C21H22ClNO2
|
1
|
| 1 |
Ki = 242.29 nM
|
|
|
|
CP0328621
|
2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H16ClFN2O
|
1
|
| 1 |
Ki = 247 nM
|
|
|
|
CP0142333
|
3-(4-chlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H14ClN
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0285757
|
2-[(3R)-3-(3,4-dichlorophenyl)piperidin-3-yl]ethanol
Show/Hide
|
C13H17Cl2NO
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0306661
|
5-(2-(2-methoxyethyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C14H20N4O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0844804
|
5-(2-benzylpiperazin-1-yl)-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C18H20N4
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0382109
|
1-[4-(2-chlorophenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C14H15ClN2O
|
1
|
| 1 |
Ki = 255 nM
|
|
|
|
CP0307516
|
(S)-2-chloro-4-fluoro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C15H20ClFN2O
|
1
|
| 1 |
Ki = 263 nM
|
|
|
|
CP0395158
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-vinyl-phenylamine
Show/Hide
|
C17H20N2S
|
1
|
| 1 |
Ki = 269 nM
|
|
|
|
CP0522068
|
Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine
Show/Hide
|
C17H20N2
|
1
|
| 1 |
Ki = 271 nM
|
|
|
|
CP0308910
|
2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C17H19FN2O2
|
1
|
| 1 |
Ki = 276 nM
|
|
|
|
CP0221672
|
2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C17H20N2O2
|
1
|
| 1 |
Ki = 292 nM
|
|
|
|
CP0127591
|
(S)-N-isobutyl-N-(pyrrolidin-3-yl)biphenyl-2-carboxamide
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
Ki = 294 nM
|
|
|
|
CP0433280
|
1-[4-(2-methoxyphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine
Show/Hide
|
C16H20N2O2
|
1
|
| 1 |
Ki = 296 nM
|
|
|
|
CP0378120
|
[3-amino-4-[2-[(dimethylamino)methyl]phenyl]sulfanylphenyl]methanol
Show/Hide
|
C16H20N2OS
|
2
|
| 1 |
Ki = 303 nM
|
|
|
| 2 |
Ki = 787.4 nM
|
|
|
|
CP0165816
|
5-(2-((tetrahydro-2H-pyran-4-yl)methyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C17H24N4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0236510
|
5-(2-(methoxymethyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C13H18N4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0278571
|
(R)-5-(2-((tetrahydro-2H-pyran-4-yl)methyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C17H24N4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0335944
|
5-(2-(ethoxymethyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C14H20N4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0360683
|
3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0415212
|
1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)piperazine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0758316
|
(R)-2-((R)-(2,3-dihydrobenzofuran-7-yloxy)(phenyl)methyl)morpholine
Show/Hide
|
C19H21NO3
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0404932
|
1-[4-(2-ethylphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C16H20N2O
|
1
|
| 1 |
Ki = 366 nM
|
|
|
|
CP0404680
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-ethyl-phenylamine
Show/Hide
|
C17H22N2S
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0913961
|
2-benzyl-1-phenylpiperazine
Show/Hide
|
C17H20N2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0429973
|
2-[2-[(dimethylamino)methyl]-4-(4-fluorobutoxy)phenoxy]-5-methylaniline
Show/Hide
|
C20H27FN2O2
|
1
|
| 1 |
Ki = 406 nM
|
|
|
|
CP0226678
|
2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H16Cl2N2O
|
1
|
| 1 |
Ki = 413 nM
|
|
|
|
CP0439217
|
4-(2-phenoxyphenyl)piperidine
Show/Hide
|
C17H19NO
|
1
|
| 1 |
Ki = 416 nM
|
|
|
|
CP0843469
|
(R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C18H20ClNO3
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0508810
|
methyl (1R,2S,3S,5S)-3-(4-methylphenyl)-8-[(Z)-4,4,4-trifluoro-3-iodobut-2-enyl]-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
|
C20H23F3INO2
|
1
|
| 1 |
Ki = 426 nM
|
|
|
|
CP0262845
|
2-[(3S)-3-(1-benzofuran-2-yl)piperidin-3-yl]ethanol
Show/Hide
|
C15H19NO2
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0334040
|
3-(3-chlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H14ClN
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0129619
|
N-[3-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
|
C27H34N4O2S
|
1
|
| 1 |
Ki = 436 nM
|
|
|
|
CP0382108
|
N-methyl-1-[6-methyl-4-(2-propylphenoxy)pyridin-3-yl]methanamine
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki = 438 nM
|
|
|
|
CP0857443
|
6-methoxy-2-methyl-3-((S)-3-methyl-1-((R)-pyrrolidin-3-yl)butoxy)pyridine
Show/Hide
|
C16H26N2O2
|
1
|
| 1 |
Ki = 438 nM
|
|
|
|
CP0393524
|
5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phenylamine
Show/Hide
|
C16H20N2S
|
1
|
| 1 |
Ki = 445.36 nM
|
|
|
|
CP0475700
|
3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Show/Hide
|
C18H22INO2
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0314578
|
4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-fluoro-N-(4-fluorophenyl)anilino)butyl]piperidin-4-ol
Show/Hide
|
C28H28ClF5N2O
|
1
|
| 1 |
Ki = 458 nM
|
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CP0422350
|
1-[4-(2-ethoxyphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
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C16H20N2O2
|
1
|
| 1 |
Ki = 461 nM
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CP0498683
|
N-[(3S)-1-methylpyrrolidin-3-yl]-N-[(2-phenylphenyl)methyl]ethanesulfonamide
Show/Hide
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C20H26N2O2S
|
1
|
| 1 |
Ki = 466 nM
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CP0395160
|
[3-amino-4-[2-(methylaminomethyl)phenyl]sulfanylphenyl]methanol
Show/Hide
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C15H18N2OS
|
1
|
| 1 |
Ki = 483.55 nM
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CP0879631
|
4-(2-benzylpiperazin-1-yl)-N-methylaniline
Show/Hide
|
C18H23N3
|
1
|
| 1 |
Ki = 501.19 nM
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CP0904684
|
5-(2-benzylpiperazin-1-yl)-1H-indole-2-carboxamide
Show/Hide
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C20H22N4O
|
1
|
| 1 |
Ki = 501.19 nM
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CP0485331
|
4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenoxy)-benzylamine
Show/Hide
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C16H19FN2O
|
1
|
| 1 |
Ki = 503 nM
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CP0082560
|
4-[4-chloro-3-(trifluoromethyl)phenyl]-1-(4,4-diphenylbutyl)piperidin-4-ol
Show/Hide
|
C28H29ClF3NO
|
1
|
| 1 |
Ki = 518 nM
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CP0373802
|
1-(2-(2-fluorobenzyloxy)phenyl)piperazine
Show/Hide
|
C17H19FN2O
|
1
|
| 1 |
Ki = 526 nM
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CP0128796
|
2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H17FN2O
|
1
|
| 1 |
Ki = 536 nM
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CP0373800
|
1-(2-phenoxyphenyl)piperazine
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
Ki = 554 nM
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CP0198910
|
(R)-N-(cyclobutylmethyl)-2-(methylthio)-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C17H24N2OS
|
1
|
| 1 |
Ki = 572 nM
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CP0168317
|
1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
Show/Hide
|
C28H27ClF5NO
|
1
|
| 1 |
Ki = 588 nM
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CP0795319
|
(R)-2-((R)-(4-fluoro-2-methoxyphenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C18H20FNO3
|
1
|
| 1 |
Ki = 610 nM
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CP0376590
|
2-[2-[(dimethylamino)methyl]-4-(3-fluoropropoxy)phenoxy]-5-methylaniline
Show/Hide
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C19H25FN2O2
|
1
|
| 1 |
Ki = 632 nM
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CP0447659
|
4-(2,4-difluorophenyl)-2-(2-(piperazin-1-yl)benzylidene)thiomorpholin-3-one
Show/Hide
|
C21H21F2N3OS
|
1
|
| 1 |
Ki = 650 nM
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CP0046327
|
1-(2-(2-chloro-6-fluorophenoxy)pyridin-3-yl)piperazine
Show/Hide
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C15H15ClFN3O
|
1
|
| 1 |
Ki = 663 nM
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CP0392037
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoromethyl-phenylamine
Show/Hide
|
C16H19FN2S
|
1
|
| 1 |
Ki = 663.8 nM
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CP0407042
|
2-[2-[(dimethylamino)methyl]-4-(2-fluoroethoxy)phenoxy]-5-methylaniline
Show/Hide
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C18H23FN2O2
|
1
|
| 1 |
Ki = 667 nM
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CP0358061
|
2-(2-((dimethylamino)methyl)phenylthio)-5-iodoaniline
Show/Hide
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C15H17IN2S
|
2
|
| 1 |
Ki = 699 nM
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| 2 |
Ki = 1352 nM
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CP0896041
|
[C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-6-methoxy-1,2,3,4-tetrahydro isoquinoline
Show/Hide
|
C21H23IN2O
|
1
|
| 1 |
Ki = 712 nM
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CP0336113
|
1-(2-(2-chlorophenoxy)pyridin-3-yl)piperazine
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
Ki = 747 nM
|
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CP0514571
|
N-[(3S)-1-methylpyrrolidin-3-yl]-N-[(2-phenylphenyl)methyl]methanesulfonamide
Show/Hide
|
C19H24N2O2S
|
1
|
| 1 |
Ki = 748 nM
|
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CP0388357
|
3-[4-[6-(3-fluoropropoxy)-3,4-dihydro-1H-isoquinolin-2-yl]cyclohexyl]-1H-indole-5-carbonitrile
Show/Hide
|
C27H30FN3O
|
1
|
| 1 |
Ki = 772 nM
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CP0102699
|
(R)-N-(cyclobutylmethyl)-2-isopropyl-N-(pyrrolidin-3-yl)benzamide
Show/Hide
|
C19H28N2O
|
1
|
| 1 |
Ki = 825 nM
|
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CP0684565
|
(R)-2-((R)-(2-chloro-4-fluorophenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C17H17ClFNO2
|
1
|
| 1 |
Ki = 830 nM
|
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CP0824488
|
(R)-2-((R)-(4-fluoro-2-methylphenoxy)(phenyl)methyl)morpholine
Show/Hide
|
C18H20FNO2
|
1
|
| 1 |
Ki = 860 nM
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CP0069223
|
4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[3-(4-fluoro-N-(4-fluorophenyl)anilino)propyl]piperidin-4-ol
Show/Hide
|
C27H26ClF5N2O
|
1
|
| 1 |
Ki = 902 nM
|
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CP0422352
|
1-[4-(2-methoxyphenoxy)-6-methylpyridin-3-yl]-N-methylmethanamine
Show/Hide
|
C15H18N2O2
|
1
|
| 1 |
Ki = 921 nM
|
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CP0341712
|
2-(2-fluoro-4-methylphenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C17H19FN2O
|
1
|
| 1 |
Ki = 921 nM
|
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CP0003459
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H37N5OS
|
1
|
| 1 |
Ki = 931 nM
|
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CP0431235
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluoro-ethyl)-phenylamine
Show/Hide
|
C17H21FN2S
|
2
|
| 1 |
Ki = 946.2 nM
|
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| 2 |
Ki > 5000 nM
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CP0427826
|
N-methyl-1-[6-methyl-4-(2-methylphenoxy)pyridin-3-yl]methanamine
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
Ki = 951 nM
|
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CP0437783
|
3-[4-(6-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-cyclohexyl]-1H-indole-5-carbonitrile
Show/Hide
|
C25H27N3O
|
1
|
| 1 |
Ki = 1020 nM
|
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CP0389578
|
benzyl 7-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylate
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 1059 nM
|
|
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CP0527786
|
5-[(2-fluorophenoxy)methyl]-3-[[(2S)-pyrrolidin-2-yl]methoxy]-1,2-oxazole;hydrochloride
Show/Hide
|
C15H18ClFN2O3
|
1
|
| 1 |
Ki = 1082 nM
|
|
|
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CP0254260
|
(R)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
Show/Hide
|
C17H21F3N2O
|
1
|
| 1 |
Ki = 1120 nM
|
|
|
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CP0503554
|
2beta-Carbo(2-fluoroethoxy)-3beta-(3'-((E)-2-iodoethenyl)phenyl)-nortropane
Show/Hide
|
C18H21FINO2
|
1
|
| 1 |
Ki = 1180 nM
|
|
|
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CP0057295
|
(R)-Nomifensine
Show/Hide
|
C16H18N2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
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CP0390505
|
4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine
Show/Hide
|
C16H19FN2S
|
1
|
| 1 |
Ki = 1203 nM
|
|
|
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CP0470064
|
2-(2-((dimethylamino)methyl)-4-fluorophenoxy)-5-methylbenzenamine
Show/Hide
|
C16H19FN2O
|
1
|
| 1 |
Ki = 1245 nM
|
|
|
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CP0111182
|
benzyl 5-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-1,3-dihydroisoindole-2-carboxylate
Show/Hide
|
C25H31N3O4
|
1
|
| 1 |
Ki = 1312 nM
|
|
|
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CP0437911
|
3-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-cyclohexyl]-1H-indole-5-carbonitrile
Show/Hide
|
C24H25N3
|
1
|
| 1 |
Ki = 1430 nM
|
|
|
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CP0202831
|
4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-methoxy-N-(4-methoxyphenyl)anilino)butyl]piperidin-4-ol
Show/Hide
|
C30H34ClF3N2O3
|
1
|
| 1 |
Ki = 1438 nM
|
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CP0231710
|
5-(2-(cyclohexylmethyl)piperazin-1-yl)-1H-indazole
Show/Hide
|
C18H26N4
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
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CP0918264
|
[C11]-2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-6-methoxy-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C21H23FN2O
|
1
|
| 1 |
Ki = 1680 nM
|
|
|
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CP0373815
|
1-(2-(4-fluorophenoxy)phenyl)piperazine
Show/Hide
|
C16H17FN2O
|
1
|
| 1 |
Ki = 1710 nM
|
|
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CP0472699
|
4-(2-(phenoxymethyl)phenyl)piperidine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 1710 nM
|
|
|
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CP0439165
|
1-(2-(3-fluorophenoxy)phenyl)piperazine
Show/Hide
|
C16H17FN2O
|
1
|
| 1 |
Ki = 1720 nM
|
|
|
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CP0930404
|
[C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-5-methoxy-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C21H23IN2O
|
1
|
| 1 |
Ki = 1810 nM
|
|
|
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CP0181469
|
2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H16F2N2O
|
1
|
| 1 |
Ki = 1810 nM
|
|
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CP0117807
|
4-[4-[1-[4-[1-(6-aminohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
Show/Hide
|
C41H46F3N5O2
|
1
|
| 1 |
Ki = 1870 nM
|
|
|
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CP0373806
|
4-(2-((3-fluorophenoxy)methyl)phenyl)piperidine
Show/Hide
|
C18H20FNO
|
1
|
| 1 |
Ki = 1940 nM
|
|
|
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CP0527787
|
5-[(2-chlorophenoxy)methyl]-3-[[(2S)-pyrrolidin-2-yl]methoxy]-1,2-oxazole;hydrochloride
Show/Hide
|
C15H18Cl2N2O3
|
1
|
| 1 |
Ki = 2109 nM
|
|
|
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CP0360682
|
2-phenoxy-3-(piperidin-4-yl)pyridine
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
Ki = 2440 nM
|
|
|
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CP0868251
|
[C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-6-methoxy-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C21H23BrN2O
|
1
|
| 1 |
Ki = 2770 nM
|
|
|
|
CP0909107
|
(1R,2R,3S,4R,5S)-1-methyl-4-(6-(phenethylamino)-2-(phenylethynyl)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H27N5O2
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0919123
|
[C11]-2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C21H23FN2O
|
1
|
| 1 |
Ki = 2880 nM
|
|
|
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CP0076892
|
(2S,3S,4R,5R)-5-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(propylamino)purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C20H21ClN6O4S
|
1
|
| 1 |
Ki = 3100 nM
|
|
|
|
CP0042095
|
(8S)-N-[2-(3-fluorophenyl)ethyl]pentacyclo[5.4.0.02,6.03,10.05,9]undecan-8-amine
Show/Hide
|
C19H22FN
|
1
|
| 1 |
Ki = 3623 nM
|
|
|
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CP0484142
|
2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phenylamine
Show/Hide
|
C17H20N2S
|
1
|
| 1 |
Ki = 3823 nM
|
|
|
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CP0484161
|
2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl}-5-methyl-phenylamine
Show/Hide
|
C16H19FN2S
|
1
|
| 1 |
Ki = 3910 nM
|
|
|
|
CP0377951
|
2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfanyl}-5-methyl-phenylamine
Show/Hide
|
C17H21FN2S
|
1
|
| 1 |
Ki = 4332 nM
|
|
|
|
CP0494981
|
2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylamine
Show/Hide
|
C14H16N2S
|
1
|
| 1 |
Ki = 4440 nM
|
|
|
|
CP0229064
|
3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile
Show/Hide
|
C16H17N3S
|
1
|
| 1 |
Ki = 5127 nM
|
|
|
|
CP0477989
|
4-hydroxy-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
Show/Hide
|
C18H11F3O3
|
1
|
| 1 |
Ki = 5800 nM
|
|
|
|
CP0053445
|
(8S)-N-[(3-fluorophenyl)methyl]pentacyclo[5.4.0.02,6.03,10.05,9]undecan-8-amine
Show/Hide
|
C18H20FN
|
1
|
| 1 |
Ki = 5883 nM
|
|
|
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CP0041749
|
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
Show/Hide
|
C20H21FN2O
|
1
|
| 1 |
Ki = 6190 nM
|
|
|
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CP0914365
|
[C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-5-methoxy-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C21H23BrN2O
|
1
|
| 1 |
Ki = 6600 nM
|
|
|
|
CP0487126
|
2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-5-methyl-phenylamine
Show/Hide
|
C16H19FN2S
|
1
|
| 1 |
Ki = 7036 nM
|
|
|
|
CP0072370
|
(8S)-N-(1,3-benzodioxol-5-ylmethyl)pentacyclo[5.4.0.02,6.03,10.05,9]undecan-8-amine
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki = 7352 nM
|
|
|
|
CP0490784
|
2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phenylamine
Show/Hide
|
C16H20N2S
|
1
|
| 1 |
Ki = 7552 nM
|
|
|
|
CP0669838
|
(S)-N-(3-(3-Fluorophenyl)propyl)-N-methyl-11-aminopentacyclo[5.4.0.02,6.03,10.05,9]undecan-8-one
Show/Hide
|
C21H24FNO
|
1
|
| 1 |
Ki = 8533 nM
|
|
|
|
CP0491189
|
2-[2-[(dimethylamino)methyl]-5-(2-fluoroethoxy)phenoxy]-5-methylaniline
Show/Hide
|
C18H23FN2O2
|
1
|
| 1 |
Ki = 8854 nM
|
|
|
|
CP0391534
|
3-(3,4-Dihydroxy-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester
Show/Hide
|
C16H19NO4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0430328
|
3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438140
|
3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0083087
|
1-(4-Methylphenyl)-3-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0099046
|
1-(3,4-dichlorophenyl)-3-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C15H19Cl2NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0172732
|
2-pyrrolidin-1-yl-1-(4-trifluoromethylphenyl)pentan-1-one
Show/Hide
|
C16H20F3NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0403193
|
4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile
Show/Hide
|
C16H20N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0419563
|
(1R)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C16H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0432600
|
1-(4-N-methylpyrrolephenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C20H26N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0436612
|
1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one
Show/Hide
|
C17H25NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0441578
|
1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0446641
|
1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-methylpentan-1-one
Show/Hide
|
C16H21Cl2NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0500663
|
1-(4-methylphenyl)-2-pyrrolidin-1-yl-methylpentan-1-one
Show/Hide
|
C17H25NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0496807
|
5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-phenylamine
Show/Hide
|
C17H22N2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0418903
|
2-Aminoethyl-5-(4'-methoxy-1'-naphthethyl)tetrahydrofuran
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki > 10000 nM
|
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CP0437845
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2-Aminoethyl-5-(2'-methoxy-1'-naphthethyl)tetrahydrofuran
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C19H25NO2
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1
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| 1 |
Ki > 10000 nM
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CP0373895
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2-(N-Isopropylamino)-3'-chloropropiophenone
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C12H16ClNO
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1
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| 1 |
Ki > 10000 nM
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CP0373935
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2-(tert-butylamino)-7-chloro-3,4-dihydronaphthalen-1(2H)-one
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C14H18ClNO
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1
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| 1 |
Ki > 10000 nM
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CP0379316
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2-(N-Propylamino)-3'-chloropropiophenone
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C12H16ClNO
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1
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| 1 |
Ki > 10000 nM
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CP0439309
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2-tert-butyl-3-methyl-2,3-dihydroisoquinolin-4(1H)-one
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C14H18ClNO
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1
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| 1 |
Ki > 10000 nM
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CP0446604
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2-(tert-Butylamino)-3',5'-difluoropropiophenone
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C13H17F2NO
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1
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| 1 |
Ki > 10000 nM
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CP0450721
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(1R,2R)-2-(tert-butylamino)-1-phenylpropan-1-ol
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C13H21NO
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1
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| 1 |
Ki > 10000 nM
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CP0042099
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5-[(3,4-dimethoxyphenyl)methyl]-5-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-4-ol
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C20H23NO3
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1
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| 1 |
Ki > 10000 nM
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CP0054519
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(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
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C25H31F3N2
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1
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| 1 |
Ki > 10000 nM
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CP0085414
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(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
Show/Hide
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C20H27NO
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1
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| 1 |
Ki > 10000 nM
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CP0055933
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3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
Show/Hide
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C22H22FN3O3
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1
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| 1 |
Ki > 10000 nM
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CP0115748
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ethyl 1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate
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C24H26FN3O4
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1
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| 1 |
Ki > 10000 nM
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CP0437991
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N-methyl-N-[2-[[5-(phenoxymethyl)-1,2-oxazol-3-yl]oxy]ethyl]cyclohexanamine;hydrochloride
Show/Hide
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C19H27ClN2O3
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1
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| 1 |
Ki > 10000 nM
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CP0469776
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N-(cyclopropylmethyl)-N-methyl-2-[[5-(phenoxymethyl)-1,2-oxazol-3-yl]oxy]ethanamine;hydrochloride
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C17H23ClN2O3
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1
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| 1 |
Ki > 10000 nM
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CP0532506
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(1S,9S,10S)-4-(1,1-difluoroethyl)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Show/Hide
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C19H25F2N
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1
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| 1 |
Ki > 10000 nM
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CP0547087
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(1S,9S,10S)-17-methyl-4-(1,1,2,2,2-pentafluoroethyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Show/Hide
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C19H22F5N
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1
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| 1 |
Ki > 10000 nM
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CP0564569
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Dextrorphan
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C17H23NO
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1
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| 1 |
Ki > 340 nM
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CP0376589
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2-[2-[(dimethylamino)methyl]-5-(3-fluoropropoxy)phenoxy]-5-methylaniline
Show/Hide
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C19H25FN2O2
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1
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| 1 |
Ki > 500 nM
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CP0134764
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(1R,2S,3S,5S)-methyl 8-((E)-3-iodoallyl)-3-p-tolyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Show/Hide
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C19H24INO2
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1
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| 1 |
Ki > 500 nM
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CP0156479
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(+)-N-methyl-laurotetanine
Show/Hide
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C20H23NO4
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1
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| 1 |
Ki > 950 nM
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CP0492687
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N-[2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylphenyl]-4-nitrobenzamide
Show/Hide
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C23H23N3O3S
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1
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| 1 |
Ki > 1000 nM
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CP0525950
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N-[(4-fluorophenyl)methyl]-5-methyl-2-[2-(methylaminomethyl)phenyl]sulfanylaniline
Show/Hide
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C22H23FN2S
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1
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| 1 |
Ki > 1000 nM
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CP0398923
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2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-N-[(4-fluorophenyl)methyl]-5-methylaniline
Show/Hide
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C23H25FN2S
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1
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| 1 |
Ki > 1200 nM
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CP0502213
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2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methyl-N-[(4-nitrophenyl)methyl]aniline
Show/Hide
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C23H25N3O2S
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1
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| 1 |
Ki > 1900 nM
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CP0524176
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4-fluoro-N-[5-methyl-2-[2-(methylaminomethyl)phenyl]sulfanylphenyl]benzamide
Show/Hide
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C22H21FN2OS
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1
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| 1 |
Ki > 2500 nM
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CP0903357
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5-(2-benzylpiperazin-1-yl)-1H-indole-3-carboxamide
Show/Hide
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C20H22N4O
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1
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| 1 |
Ki > 5011.87 nM
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CP0502212
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N-[2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylphenyl]-4-fluorobenzamide
Show/Hide
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C23H23FN2OS
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1
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| 1 |
Ki > 5200 nM
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CP0374320
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3-Cyano-4'-(3-fluorophenyl)-N-(6-methylpyridin-2-yl)-benzamide
Show/Hide
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C20H14FN3O
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1
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| 1 |
Ki > 6000 nM
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CP0374326
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3-Cyano-4-phenyl-N-(6-methylpyridin-2-yl)-benzamide
Show/Hide
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C20H15N3O
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1
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| 1 |
Ki > 6000 nM
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CP0374365
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1-(Pyridin-3-yl)-2-fluoro-4-(2-methylthiazol-4ylethynyl)benzene
Show/Hide
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C17H11FN2S
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1
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| 1 |
Ki > 6000 nM
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CP0382061
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1-Fluoro-3-(pyridin-3-yl)-5-(2-methylthiazol-4ylethynyl)benzene
Show/Hide
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C17H11FN2S
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1
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| 1 |
Ki > 6000 nM
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