Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_136434-34-9
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 PubChem ID
CID: 60835
SID: 14873633
Canonical SMILES
CNCC[C@H](Oc1cccc2ccccc12)c1cccs1
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Compound Formula C18H19NOS
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent noradrenaline transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P23975
Gene Name
SLC6A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
IC50 = 1.585 nM
   TI
   LI
   LO
   TS
2
IC50 = 5 nM
   TI
   LI
   LO
   TS
3
IC50 = 8.9 nM
   TI
   LI
   LO
   TS
4
IC50 = 19 nM
   TI
   LI
   LO
   TS
5
IC50 = 29 nM
   TI
   LI
   LO
   TS
6
IC50 = 515 nM
   TI
   LI
   LO
   TS
7
Ki = 6.7 nM
   TI
   LI
   LO
   TS
8
Ki = 45 nM
   TI
   LI
   LO
   TS
CL000031 MDCK
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CL000882 MDCK-Net6
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.9 nM
2 Ki = 5.97 nM
3 Ki = 7.45 nM
4 Ki = 7.5 nM
5 Ki = 7.943 nM
6 Ki = 16 nM