| Compound ID |
Compound Name |
Compound Formula |
|
CP0385686
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1-ethyl-2-iodoimidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
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|
C18H25IN6O4
|
3
|
| 1 |
EC50 = 0.1 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
IC50 = 2450 nM
|
|
|
|
CP0404602
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2-iodo-1-methylimidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C17H23IN6O4
|
3
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
EC50 = 5 nM
|
|
|
| 3 |
IC50 = 69 nM
|
|
|
|
CP0403074
|
(2S)-N-[(2S)-3-(2-bromo-1-methylimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C17H23BrN6O4
|
3
|
| 1 |
EC50 = 0.46 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
IC50 = 140 nM
|
|
|
|
CP0067202
|
1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyrrolylcarboxamido)propanoyl]tetrahydro-1H-2-pyrrolecarboxamide
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|
C16H22N6O4
|
4
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
EC50 = 0.52 nM
|
|
|
| 3 |
EC50 = 3.1 nM
|
|
|
| 4 |
IC50 = 7 nM
|
|
|
|
CP0404608
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2,5-diiodo-1-methylimidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C17H22I2N6O4
|
3
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
EC50 = 39 nM
|
|
|
| 3 |
IC50 = 2240 nM
|
|
|
|
CP0385924
|
(2S)-N-[(2S)-3-(2-bromo-1-propylimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C19H27BrN6O4
|
3
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
EC50 = 25550 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
|
CP0403073
|
(2S)-N-[(2S)-3-(2-bromo-1-ethylimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C18H25BrN6O4
|
3
|
| 1 |
EC50 = 1.46 nM
|
|
|
| 2 |
EC50 = 1050 nM
|
|
|
| 3 |
IC50 = 7600 nM
|
|
|
|
CP0380486
|
(2R)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-(2-propyl-1H-imidazol-5-yl)propan-2-yl]piperidine-2-carboxamide
Show/Hide
|
C20H32N6O3
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0515385
|
3-amino-N-[(2S)-3-(4-bromo-1H-imidazol-5-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C16H19BrN8O3
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0404607
|
(2S)-N-[(2S)-3-(1-benzyl-2,5-diiodoimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C23H26I2N6O4
|
3
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
EC50 = 30 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
|
CP0455656
|
(2S)-N-[(2S)-3-(1-benzyl-2-iodoimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C23H27IN6O4
|
3
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
EC50 = 27 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
|
CP0385687
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1-ethyl-2,5-diiodoimidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C18H24I2N6O4
|
3
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 38 nM
|
|
|
| 3 |
IC50 = 15620 nM
|
|
|
|
CP0848540
|
N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-1-oxo-3-(2-propyl-1H-imidazol-4-yl)propan-2-yl)-5-methylpyrazine-2-carboxamide
Show/Hide
|
C20H27N7O3
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0380508
|
N-[(2S)-3-(5-bromo-1-methylimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C17H20BrN7O3
|
2
|
| 1 |
EC50 = 30 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0429046
|
N-[(2S)-3-(1-benzyl-2,5-diiodoimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C23H23I2N7O3
|
2
|
| 1 |
EC50 = 30 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0380484
|
N-[(2S)-3-(4-bromo-1H-imidazol-5-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-methylpyrazine-2-carboxamide
Show/Hide
|
C17H20BrN7O3
|
2
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0431506
|
N-[(2S)-3-(4-bromo-1H-imidazol-5-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C16H18BrN7O3
|
2
|
| 1 |
EC50 = 48 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0045937
|
N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2,4-dibromo-1H-imidazol-5-yl)-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C16H17Br2N7O3
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0380507
|
N-[(2S)-3-(1-benzyl-2,5-diiodoimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-methylpyrazine-2-carboxamide
Show/Hide
|
C24H25I2N7O3
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0404605
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2-chloro-1-methylimidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C17H23ClN6O4
|
3
|
| 1 |
EC50 = 51 nM
|
|
|
| 2 |
EC50 = 87 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
|
CP0867216
|
N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-1-oxo-3-(2-propyl-1H-imidazol-4-yl)propan-2-yl)pyrazine-2-carboxamide
Show/Hide
|
C19H25N7O3
|
2
|
| 1 |
EC50 = 60 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0382215
|
N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2,4-dibromo-1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-methylpyrazine-2-carboxamide
Show/Hide
|
C17H19Br2N7O3
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0380485
|
3-amino-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-(2-propyl-1H-imidazol-5-yl)propan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C19H26N8O3
|
2
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0448149
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2,5-diiodo-1-propylimidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C19H26I2N6O4
|
3
|
| 1 |
EC50 = 206 nM
|
|
|
| 2 |
EC50 = 350 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
|
CP0867217
|
3-amino-N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-3-(2,5-dibromo-1H-imidazol-4-yl)-1-oxopropan-2-yl)pyrazine-2-carboxamide
Show/Hide
|
C16H18Br2N8O3
|
2
|
| 1 |
EC50 = 290 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0849355
|
N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-3-(2,5-diiodo-1H-imidazol-4-yl)-1-oxopropan-2-yl)pyrazine-2-carboxamide
Show/Hide
|
C16H17I2N7O3
|
2
|
| 1 |
EC50 = 310 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0392458
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2,4-dichloro-1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C16H20Cl2N6O4
|
3
|
| 1 |
EC50 = 360 nM
|
|
|
| 2 |
EC50 = 380 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
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CP0515386
|
N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(4-chloro-1H-imidazol-5-yl)-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C16H18ClN7O3
|
2
|
| 1 |
EC50 = 530 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
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CP0431472
|
(2R)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-(2-propan-2-yl-1H-imidazol-5-yl)propan-2-yl]piperidine-2-carboxamide
Show/Hide
|
C20H32N6O3
|
2
|
| 1 |
EC50 = 770 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0411527
|
N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1-ethyl-2,5-diiodoimidazol-4-yl)-1-oxopropan-2-yl]pyrazine-2-carboxamide
Show/Hide
|
C18H21I2N7O3
|
2
|
| 1 |
EC50 = 960 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
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CP0385688
|
(2S)-N-[(2S)-3-(1-benzyl-2-chloroimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C23H27ClN6O4
|
3
|
| 1 |
EC50 = 1910 nM
|
|
|
| 2 |
EC50 = 8720 nM
|
|
|
| 3 |
IC50 = 13610 nM
|
|
|
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CP0392457
|
(2S)-N-[(2S)-3-(1-benzyl-2-bromoimidazol-4-yl)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C23H27BrN6O4
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0392456
|
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(2,4-diiodo-1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C16H20I2N6O4
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
