Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
    Show/Hide
 PubChem ID
CID: 104741
SID: 14911923
Canonical SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc1cc(O)ccc31
    Show/Hide
Compound Formula C32H47F5O3S
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 3.8 nM
   TI
   LI
   LO
   TS
CL001042 HEK293/Gal4
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM
2 IC50 = 8.4 nM
3 IC50 = 10.2 nM
4 IC50 = 21 nM
5 IC50 = 44.1 nM
6 Ki = 1.39 nM