Brief Information of the Compound and Protein
Compound Name
8-(4-chlorophenyl)-6-(2,3-dimethylbenzimidazol-5-yl)-2-(2,2,2-trifluoroethylamino)pyrido[4,3-d]pyrimidin-7-one
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PubChem ID
CID: 139551910
Canonical SMILES
Cc1nc2ccc(cc2n1C)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O
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Compound Formula C24H18ClF3N6O
Compound Structure
Protein Name
S-adenosylmethionine synthase isoform type-2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P31153
Gene Name
MAT2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 21 nM
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