Brief Information of the Compound and Protein
| Compound Name |
2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
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Protein Classification |
Enzyme
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Transferase
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| Uniprot ID | Gene Name | PIK3CA |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 < 0.7 nM | ||
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| 2 | Ki = 0.09 nM | ||
| 3 | Ki = 0.29 nM | ||
| 4 | Ki = 0.3 nM | ||