Brief Information of the Compound and Protein
| Compound Name |
9-cis retinoic acid
Show/Hide
|
PubChem ID | |||||
|
Compound Structure |
|
|||||
| Protein Name |
Retinoic acid receptor RXR-beta
|
Protein Classification |
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 2
>
Nuclear hormone receptor subfamily 2 group B
>
Nuclear hormone receptor subfamily 2 group B member 2
|
||||
| Uniprot ID | Gene Name | RXRB |
|||||
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000044 | CV-1 | Chlorocebus aethiops (Green monkey) | 1 |
| 1 |
EC50 = 200 nM
|
TI
LI
LO
TS
|
|
|---|---|---|---|
| CL000043 | U2OS | Homo sapiens (Human) | 1 |
| 1 |
EC50 = 6 nM
|
TI
LI
LO
TS
|
|
Biochemical Assays
| 1 | EC50 = 2.6 nM | ||
|---|---|---|---|
| 2 | EC50 = 200 nM | ||
| 3 | IC50 = 12 nM | ||
| 4 | Kd = 11 nM | ||
| 5 | Kd = 15 nM | ||
| 6 | Kd = 35 nM | ||
| 7 | Ki = 7.4 nM | ||
| 8 | Ki = 9 nM | ||