Brief Information of the Compound and Protein
Compound Name
6-[2-[5-cyclopropyl-3-(3,5-dichloropyridin-4-yl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-(trifluoromethyl)quinoline-2-carboxylic acid
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PubChem ID
CID: 138592025
Canonical SMILES
OC(=O)c1cc(c2cc(ccc2n1)N1CCC2(CC(=C2)c2c(onc2-c2c(Cl)cncc2Cl)C2CC2)CC1)C(F)(F)F
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Compound Formula C30H23Cl2F3N4O3
Compound Structure
Protein Name
RNA-binding protein FXR2
Protein Classification
Unclassified protein
Uniprot ID
P51116
Gene Name
FXR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 84 nM
   TI
   LI
   LO
   TS
2
EC50 = 150 nM
   TI
   LI
   LO
   TS
CL000148 Huh-7 Homo sapiens (Human)  2
1
EC50 = 243 nM
   TI
   LI
   LO
   TS
2
EC50 = 281 nM
   TI
   LI
   LO
   TS