Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[(2S)-2-fluoropropyl]-2-[[1-[(1R,4R,5S)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl]pyrazol-4-yl]amino]-4-[(1-methylcyclopropyl)amino]pyrido[4,3-d]pyrimidin-5-one
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 PubChem ID
CID: 168272591
Canonical SMILES
C[C@H](F)Cn1ccc2nc(Nc3cnn(c3)[C@H]3C[C@H]4C[C@@H]3CN4C)nc(NC3(C)CC3)c2c1=O
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Compound Formula C24H31FN8O
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000300 Karpas-299
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 79 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM