Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-methyl-2-[[1-[(1R,4R,5S)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl]pyrazol-4-yl]amino]-4-[(1-methylcyclopropyl)amino]pyrido[4,3-d]pyrimidin-5-one
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 PubChem ID
CID: 168269745
Canonical SMILES
CN1C[C@H]2C[C@@H]1C[C@@H]2n1cc(Nc2nc(NC3(C)CC3)c3c(ccn(C)c3=O)n2)cn1
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Compound Formula C22H28N8O
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000300 Karpas-299
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM