Brief Information of the Compound and Protein
Compound Name
N-[2-[3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]ethyl]-3-(trifluoromethyl)benzamide
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PubChem ID
CID: 166062943
Canonical SMILES
FC(F)(F)c1cccc(c1)C(=O)NCCc1cccc(c1)-c1cnc2[nH]ccc2c1
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Compound Formula C23H18F3N3O
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
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CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS