Brief Information of the Compound and Protein
Compound Name
(3S,4S)-8-[3-[3-chloro-2-(ethylamino)pyridin-4-yl]-2H-pyrazolo[3,4-b]pyrazin-6-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine
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PubChem ID
CID: 168282130
Canonical SMILES
CCNc1nccc(-c2n[nH]c3nc(cnc23)N2CCC3(CO[C@@H](C)[C@H]3N)CC2)c1Cl
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Compound Formula C21H27ClN8O
Compound Structure
Protein Name
Tyrosine-protein phosphatase non-receptor type 11
Protein Classification
Enzyme
>
Phosphatase
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Protein Phosphatase
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Tyrosine protein phosphatase
Uniprot ID
Q06124
Gene Name
PTPN11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000269 KYSE-520 Homo sapiens (Human)  1
1
IC50 = 22 nM
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