Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-1-(2,3-dichlorophenyl)-2-methyl-6-oxopyrimidine-5-carbonitrile
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 PubChem ID
CID: 168290220
Canonical SMILES
C[C@@H]1OCC2(CCN(CC2)c2nc(C)n(-c3cccc(Cl)c3Cl)c(=O)c2C#N)[C@@H]1N
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Compound Formula C21H23Cl2N5O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein phosphatase non-receptor type 11
Protein Classification
Enzyme
>
Phosphatase
>
Protein Phosphatase
>
Tyrosine protein phosphatase
Uniprot ID
Q06124
Gene Name
PTPN11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000269 KYSE-520
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3081 nM
   TI
   LI
   LO
   TS