Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]propanoic acid
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 PubChem ID
CID: 151929930
Canonical SMILES
C[C@@H](C(O)=O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O
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Compound Formula C23H21ClN4O4
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
O95136
Gene Name
S1PR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
2
IC50 = 253 nM
   TI
   LI
   LO
   TS
CL000673 HFL1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 182 nM
   TI
   LI
   LO
   TS
2
IC50 = 3180 nM
   TI
   LI
   LO
   TS