Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-chloro-5-methyl-2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
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 PubChem ID
CID: 164675038
Canonical SMILES
Cc1cc(C(O)=O)c2oc(CNC(=O)c3cnn4cccnc34)c(Cl)c2c1
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Compound Formula C18H13ClN4O4
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 57000 nM
   TI
   LI
   LO
   TS
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  6
1
EC50 = 5900 nM
   TI
   LI
   LO
   TS
2
EC50 = 11000 nM
   TI
   LI
   LO
   TS
3
EC50 = 15000 nM
   TI
   LI
   LO
   TS
4
EC50 = 21000 nM
   TI
   LI
   LO
   TS
5
EC50 = 34000 nM
   TI
   LI
   LO
   TS
6
EC50 = 35000 nM
   TI
   LI
   LO
   TS
CL000494 THP1-Dual
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 63000 nM
   TI
   LI
   LO
   TS
CL000585 THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 32000 nM
2 EC50 = 52000 nM
3 IC50 = 11000 nM
4 IC50 = 28000 nM