Brief Information of the Compound and Protein
Compound Name
8-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-2-(2-methyl-5-oxo-2H-furan-3-yl)-2,8-diazaspiro[4.5]decan-1-one
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PubChem ID
CID: 72950078
Canonical SMILES
CC1OC(=O)C=C1N1CCC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C1=O
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Compound Formula C24H28N2O6
Compound Structure
Protein Name
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 24 nM
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