Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-chloro-6-ethoxypyridin-4-yl)-3-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]urea
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Canonical SMILES
CCOc1cc(NC(=O)NCc2cc(C)c(cn2)-c2cn(C)nc2C)cc(Cl)n1
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Compound Formula C20H23ClN6O2
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
O95136
Gene Name
S1PR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 0.32 nM
   TI
   LI
   LO
   TS
2
IC50 = 40 nM
   TI
   LI
   LO
   TS
3
IC50 = 4700 nM
   TI
   LI
   LO
   TS
CL000673 HFL1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.032 nM
   TI
   LI
   LO
   TS