Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4,6-dichloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
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Canonical SMILES
Cc1nn(C)cc1-c1cnc(CNC(=O)c2cc3c(Cl)nc(Cl)cc3[nH]2)cc1C
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Compound Formula C20H18Cl2N6O
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
O95136
Gene Name
S1PR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 890 nM
   TI
   LI
   LO
   TS
3
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CL000673 HFL1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS