Brief Information of the Compound and Protein
Compound Name
US10781182, Compound IA2-120
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PubChem ID
CID: 139451761
Canonical SMILES
CCOc1nc2ccc(OC)cc2n1CCCNC(C)=O
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Compound Formula C15H21N3O3
Compound Structure
Protein Name
Melatonin receptor type 1B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine-derivative receptor (family A GPCR)
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Melatonin receptor
Uniprot ID
P49286
Gene Name
MTNR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.35 nM
   TI
   LI
   LO
   TS
2
Ki = 4.5 nM
   TI
   LI
   LO
   TS