Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[4-(difluoromethoxy)phenyl]-(2-fluorophenyl)-hydroxymethyl]-1-ethyl-N-(1-ethyl-1,2,4-triazol-3-yl)-5-methoxyimidazo[4,5-b]pyridine-6-carboxamide
    Show/Hide
Canonical SMILES
CCn1cnc(NC(=O)c2cc3n(CC)c(nc3nc2OC)C(O)(c2ccc(OC(F)F)cc2)c2ccccc2F)n1
    Show/Hide
Compound Formula C28H26F3N7O4
Compound Structure
Protein Name
 Protein Info 
Acetyl-coenzyme A synthetase, cytoplasmic
Protein Classification
Enzyme
>
Ligase
Uniprot ID
Q9NR19
Gene Name
ACSS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000591 HCT 15
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 0.01 nM
   TI
   LI
   LO
   TS
2
IC50 = 1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.01 nM