Brief Information of the Compound and Protein
| Compound Name |
GSK2126458
Show/Hide
|
PubChem ID | |||||
|
Compound Structure |
|
|||||
| Protein Name |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
|
Protein Classification |
Enzyme
>
Transferase
|
||||
| Uniprot ID | Gene Name | PIK3CA |
|||||
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000012 | Sf21 | Spodoptera frugiperda (Fall armyworm) | 1 |
| 1 |
IC50 = 1 nM
|
TI
LI
LO
TS
|
|
|---|---|---|---|
Biochemical Assays
| 1 | IC50 = 0.04 nM | ||
|---|---|---|---|
| 2 | IC50 = 0.3 nM | ||
| 3 | IC50 = 0.34 nM | ||
| 4 | IC50 = 0.41 nM | ||
| 5 | IC50 = 0.55 nM | ||
| 6 | IC50 = 0.63 nM | ||
| 7 | IC50 = 1.02 nM | ||
| 8 | IC50 = 1.1 nM | ||
| 9 | Ki = 0.019 nM | ||