Brief Information of the Compound and Protein
Compound Name
5-L-isoleucineangiotensin II
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PubChem ID
CID: 172198
SID: 14816795
Canonical SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
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Compound Formula C50H71N13O12
Compound Structure
Protein Name
Type-2 angiotensin II receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Angiotensin receptor
Uniprot ID
P50052
Gene Name
AGTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 0.08 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.617 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.5 nM
2 Ki = 0.2 nM
3 Ki = 0.23 nM
4 Ki = 1.2 nM