Brief Information of the Compound and Protein
| Compound Name |
6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Tryptophan 2,3-dioxygenase
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Protein Classification |
Enzyme
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Oxidoreductase
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| Uniprot ID | Gene Name | TDO2 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000784 | P815B | Mus musculus (Mouse) | 1 |
| 1 |
IC50 = 280 nM
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TI
LI
LO
TS
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|---|---|---|---|
| CL000102 | U-87MG ATCC | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 280 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 280 nM | ||
|---|---|---|---|
| 2 | IC50 = 350 nM | ||
| 3 | IC50 = 376.5 nM | ||
| 4 | IC50 = 937 nM | ||
| 5 | IC50 = 1300 nM | ||