Brief Information of the Compound and Protein
Compound Name
 Compound Info 
AS-1404
    Show/Hide
 PubChem ID
CID: 123964
SID: 57304371
Canonical SMILES
Cc1ccc2c(oc3c(CC(O)=O)cccc3c2=O)c1C
    Show/Hide
Compound Formula C17H14O4
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q3TBT3
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 35200 nM
   TI
   LI
   LO
   TS
CL000584 RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 48000 nM
   TI
   LI
   LO
   TS
CL000586 RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 15000 nM
2 IC50 = 1200 nM
3 Kd = 130 nM
4 Kd = 710 nM