Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-[(1S,6R,8R,9R,10S,15R,17R,18R)-17-(6-aminopurin-9-yl)-3,9,12,18-tetrahydroxy-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]-1H-purin-6-one
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 PubChem ID
CID: 136247207
Canonical SMILES
Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]([C@@H]3O)n1cnc2c(O)ncnc12
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Compound Formula C20H23N9O13P2
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q3TBT3
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 8400 nM
   TI
   LI
   LO
   TS
CL000584 RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 7500 nM
   TI
   LI
   LO
   TS
CL000586 RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 180 nM
2 IC50 = 7.7 nM