Brief Information of the Compound and Protein
Compound Name
(3R,4S)-8-[6-amino-5-(2-amino-3-chloropyridin-4-yl)sulfanylpyrazin-2-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine
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PubChem ID
CID: 118247772
Canonical SMILES
C[C@H]1OCC2(CCN(CC2)c2cnc(Sc3ccnc(N)c3Cl)c(N)n2)[C@@H]1N
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Compound Formula C18H24ClN7OS
Compound Structure
Protein Name
Tyrosine-protein phosphatase non-receptor type 11
Protein Classification
Enzyme
>
Phosphatase
>
Protein Phosphatase
>
Tyrosine protein phosphatase
Uniprot ID
Q06124
Gene Name
PTPN11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000269 KYSE-520 Homo sapiens (Human)  1
1
IC50 = 28 nM
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