Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US11001561, Compound 109
    Show/Hide
 PubChem ID
CID: 155165251
Canonical SMILES
Cc1nc(N2CCC3(Cc4ccccc4[C@H]3N)CC2)c(C)c(=O)n1-c1ccc(F)c(Cl)c1Cl
    Show/Hide
Compound Formula C25H25Cl2FN4O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein phosphatase non-receptor type 11
Protein Classification
Enzyme
>
Phosphatase
>
Protein Phosphatase
>
Tyrosine protein phosphatase
Uniprot ID
Q06124
Gene Name
PTPN11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000269 KYSE-520
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS