Brief Information of the Compound and Protein
Compound Name
(3S)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1H-indol-2-one
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PubChem ID
CID: 145946114
Canonical SMILES
Cc1ncc(cn1)-c1ccn2ncc(-c3ccc4NC(=O)[C@@](C)(Cc5ccccc5)c4c3)c2n1
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Compound Formula C27H22N6O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O00329
Gene Name
PIK3CD
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM