Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9546153, ex. 9
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 PubChem ID
CID: 90155292
Canonical SMILES
CC(C)(O)CCNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC1CC1
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Compound Formula C21H25N5O2S
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM