Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
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 PubChem ID
CID: 71621488
Canonical SMILES
FC1(F)C[C@@H](C#N)N(C1)C(=O)CNC(=O)c1ccnc2ccccc12
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Compound Formula C17H14F2N4O2
Compound Structure
Protein Name
 Protein Info 
Prolyl endopeptidase FAP
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9B subfamily
Uniprot ID
Q12884
Gene Name
FAP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000090 Schneider 2
 Cell Line Info 
Drosophila melanogaster (Fruit fly)  1
1
IC50 = 2.3 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 41.62 nM
   TI
   LI
   LO
   TS
2
IC50 = 55 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.3 nM