Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[2-[(3S,4S)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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 PubChem ID
CID: 156017360
Canonical SMILES
F[C@H]1CNCC[C@@H]1n1cc2cc(cc(c2n1)C(F)(F)F)-c1ccc(=O)n2CCCc12
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Compound Formula C21H20F4N4O
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor type 1
Protein Classification
Membrane receptor
Uniprot ID
P14778
Gene Name
IL1R1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 6500 nM
   TI
   LI
   LO
   TS