Brief Information of the Compound and Protein
Compound Name
 Compound Info 
SID50106398
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 PubChem ID
CID: 139087706
SID: 15322134
Canonical SMILES
Cl.Cl.NCCc1c[nH]cn1
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Compound Formula C5H11Cl2N3
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
2
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CL000913 HEK293T-SP-FLAG-hH3R-CRE-CBR
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3.311 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
Ki = 10 nM
   TI
   LI
   LO
   TS
2
Ki = 18.62 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 10 nM
   TI
   LI
   LO
   TS