Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(4-((1R,5S)-8-oxa-3-azabicyclo[3.2.1]octan-3-yl)phenyl)-6-(1H-indazol-6-yl)imidazo[1,2-a]pyrazin-8-amine
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 PubChem ID
CID: 156014856
Canonical SMILES
c1cn2cc(-c3ccc4cn[nH]c4c3)nc(Nc3ccc(N4C[C@H]5CC[C@@H](C4)O5)cc3)c2n1
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Compound Formula C25H23N7O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 162 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.3 nM