Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-(6,6-dimethyl-3-azabicyclo[3.1.0]hexane-3-carbonyl)-5-methyl-1H-pyrazol-1-yl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
    Show/Hide
 PubChem ID
CID: 137049517
Canonical SMILES
Cc1c(C(=O)N2CC3C(C2)C3(C)C)cnn1-c1nc2c(c(=O)[nH]1)CCC2
    Show/Hide
Compound Formula C19H23N5O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CL000151 SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM