Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(5-methyl-4-(4-(1,1,1-trifluoropropan-2-yl)piperazine-1-carbonyl)-1H-pyrazol-1-yl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
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 PubChem ID
CID: 137049584
Canonical SMILES
Cc1c(C(=O)N2CCN(C(C)C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2
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Compound Formula C19H23F3N6O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CL000151 SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM