Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-(3-(3,3-difluoropyrrolidin-1-yl)azetidine-1-carbonyl)-1H-1,2,3-triazol-1-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one
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 PubChem ID
CID: 137049814
Canonical SMILES
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CC(N2CCC(F)(F)C2)C1
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Compound Formula C16H16F2N8O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM